期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 18, 期 6, 页码 1784-1787出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2008.02.029
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We report herein the SAR studies of a series of indole- and indolizine-glyoxylamides that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance ( MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types of various origins ( e. g., breast, colon, uterine). (C) 2008 Elsevier Ltd. All rights reserved.
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