4.5 Article

Synthesis and biological evaluation of C-12′ substituted vinflunine derivatives

期刊

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 18, 期 16, 页码 4602-4605

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2008.07.025

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vinflunine derivatives; synthesized; in vitro; A549 cell lines

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A series of novel C-12' substituted vinflunine derivatives have been synthesized. Several compounds in this series possess comparable in vitro cytotoxic potency against A549 cell lines. (C) 2008 Elsevier Ltd. All rights reserved.

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