期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 18, 期 1, 页码 313-317出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.10.075
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资金
- Engineering and Physical Sciences Research Council [GR/S69115/01, GR/S96555/01] Funding Source: researchfish
- Medical Research Council [G9900991B] Funding Source: researchfish
Intracellular pH in living cells is measured in real time at the single cell level using fluorescently covalently loaded microspheres as efficient carrier systems and stable sensors. The use of these sensors immobilized covalently onto polymeric particles allows analysis of intracellular pH flux over long period of time and eliminates the disadvantages such as dilution within the cell, elimination via leakage or compartmentalization. (C) 2007 Elsevier Ltd. All rights reserved.
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