期刊
BIOORGANIC & MEDICINAL CHEMISTRY
卷 19, 期 3, 页码 1023-1029出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2010.07.011
关键词
Caged fluorescence; Two-photon uncaging; Cellular imaging; Photolabile linkers
资金
- ANR [PCV 07 1-0035]
- CNRS
- French Ministry of Research
- Universite de Strasbourg
The search for chemical probes which allow a controlled fluorescence activation in living cells represent a major challenge in chemical biology. To be useful, such probes have to be specifically targeted to cellular proteins allowing thereof the analysis of dynamic aspects of this protein in its cellular environment. The present paper describes different methods which have been developed to control cellular fluorescence activation emphasizing the photochemical activation methods known to be orthogonal to most cellular components and, in addition, allowing a spatio-temporal controlled triggering of the fluorescent signal. (C) 2010 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据