Review
Biochemistry & Molecular Biology
Nadeem Siddiqui, Braja Kishori, Saranya Rao, Mohammad Anjum, Venkata Hemanth, Swati Das, Esmaiel Jabbari
Summary: Polymer scaffold material like polycaprolactone (PCL) plays a crucial role in bone tissue regeneration due to its tunable biodegradability and relatively high mechanical toughness. Electrospinning technology can produce nanofibrous matrices that mimic natural tissue extracellular matrix properties, which can be utilized to enhance the biocompatibility and hydrophilicity of PCL for bone regeneration applications.
MOLECULAR BIOTECHNOLOGY
(2021)
Article
Engineering, Electrical & Electronic
Connor P. Sherwood, Daniel C. Elkington, Michael R. Dickinson, Warwick J. Belcher, Paul C. Dastoor, Krishna Feron, Alan M. Brichta, Rebecca Lim, Matthew J. Griffith
Summary: The research demonstrates the potential application of using organic semiconductor devices as photocapacitors in neural interface technologies. By characterizing different device architectures and conducting related tests, the study explores the photoresponse mechanism, advantages, and limitations of these devices.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2021)
Article
Chemistry, Applied
O. Gil-Castell, I Ontoria-Oviedo, J. D. Badia, E. Amaro-Prellezo, P. Sepulveda, A. Ribes-Greus
Summary: Electrospun nanofibers based on polycaprolactone and gelatin, with the addition of polyaniline particles, were prepared. Controlled hydrolytic action on the polycaprolactone resulted in changes in molecular mass, crystalline structure, and surface morphology. Increased dissolution time and gelatin percentage improved degradability and biocompatibility. The addition of polyaniline promoted increased electrical conductivity and cardiomyocyte proliferation.
REACTIVE & FUNCTIONAL POLYMERS
(2022)
Article
Engineering, Biomedical
Adrian D. Juncos Bombin, Nicholas Dunne, Helen O. McCarthy
Summary: The downregulation of miR-31 and miR-132 is linked to delayed wound healing. In this study, it was hypothesized that delivering miR-31 and miR-132 intracellularly, either individually or in a blend, could enhance tissue repair. The use of a blend formulation can minimize toxicity and maximize therapeutic effects.
ACTA BIOMATERIALIA
(2023)
Review
Polymer Science
Balaji Ayyanar Chinnappan, Marimuthu Krishnaswamy, Huaizhong Xu, Md Enamul Hoque
Summary: Nanotechnology and electrospinning techniques have revolutionized the production of nanofibers and membranes with unique and variable properties. This review explores the effects of various process parameters on the characteristics of biomedical nanofibers, shedding light on the optimal conditions for producing uniform, smooth, and high-quality fibers. The applications of these nanofibers are also discussed.
Article
Materials Science, Textiles
Alishba Javeed, Shamshad Ali, Awais Khatri, Raza Ali
Summary: The study investigated the preparation of print paste formulation containing PDA polymer and applied it on cellulose ENMs through screen printing and electrospinning method to produce distinctive blue CEL ENMs. The printed ENMs exhibited good colorfastness and color strength, and showed potential as thermochromic sensors under specific conditions.
JOURNAL OF THE TEXTILE INSTITUTE
(2022)
Article
Chemistry, Physical
Lei Zhan, Lingtian Wang, Jixia Deng, Yi Zheng, Qinfei Ke, Xinrui Yang, Xing Zhang, Weitao Jia, Chen Huang
Summary: Nanogrooved microfiber scaffold shows improved cell adhesion and infiltration, making it important for tissue engineering and wound healing.
Article
Developmental Biology
Makenzie G. Bonner, Hemanth Gudapati, Xingrui Mou, Samira Musah
Summary: Microfluidic systems and organs-on-chips offer new ways to understand how microenvironmental factors contribute to cell fate decisions and physiological processes. They enable us to study how extracellular signals affect cell differentiation, how cells interact with each other, and how different tissues and organs are formed for specialized functions.
Article
Materials Science, Multidisciplinary
Mehdi Movahedi, Amin Orash Mahmoud Salehi, Fatemeh Poodineh Hajipour, Sina Etemad
Summary: This study developed a nanofibrous scaffold using poly (caprolactone), gelatin, and casein for cartilage tissue engineering. The fabricated scaffold exhibited uniform fibers, suitable mechanical properties, and good cell viability and proliferation. Therefore, the PCL/Gel/Cas nanofibrous scaffold could be a promising candidate for cartilage tissue engineering applications.
BULLETIN OF MATERIALS SCIENCE
(2022)
Article
Biotechnology & Applied Microbiology
Lorna Westwood, Elaine Emmerson, Anthony Callanan
Summary: Increased cancer rates necessitate effective treatments for radiation-induced tissue damage. This study demonstrates that incorporating retinyl acetate into electrospun fibers can mitigate the damaged microenvironment caused by radiotherapy.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Zohreh Daraeinejad, Iman Shabani
Summary: Conductive nanofibers were fabricated through electrospinning of PANI/PES using different solvents, with HFIP identified as the best solvent due to its low boiling point and surface tension. The study found that a solvent with suitable properties can lead to enhanced electrical conductivity and a shift from a flat 2D structure to a fluffy 3D structure in the resulting nanofibrous scaffold. Additionally, the optimal percentage of PES varied depending on the solvent used, with HFIP allowing for electrospinning at lower concentrations.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Polymer Science
Ulisse Montanari, Davide Cocchi, Tommaso Maria Brugo, Antonino Pollicino, Vincenzo Taresco, Maria Romero Fernandez, Jonathan C. Moore, Domenico Sagnelli, Francesca Paradisi, Andrea Zucchelli, Steven M. Howdle, Chiara Gualandi
Summary: A novel bio-based polymer was developed and incorporated into poly(vinylidene fluoride) fibers through a simple electrospinning process, resulting in functionalizable epoxy groups at the fiber surface. This new method has the potential for widespread application in the functionalization of fiber materials, demonstrated in applications such as carbon fiber reinforced composites and enzyme immobilization membranes.
Article
Biochemistry & Molecular Biology
Liszt Y. C. Madruga, Rosangela C. Balaban, Ketul C. Popat, Matt J. Kipper
Summary: A new type of biocompatible nanofibers based on PVA and CMKC blends were produced without hazardous waste generation. The incorporation of CMKC improved cytocompatibility, biodegradability, cell growth, and cell adhesion, making these nanofibers good candidates for supporting stem cells in tissue engineering applications. The nanofibers were stabilized by thermal crosslinking and showed modulation of human ADSC phenotype towards osteogenic differentiation signals.
MACROMOLECULAR BIOSCIENCE
(2021)
Review
Materials Science, Multidisciplinary
Xiao-Xiong Wang, Gui-Feng Yu, Jun Zhang, Miao Yu, Seeram Ramakrishna, Yun-Ze Long
Summary: Electrospinning is a versatile technique for mass fabrication of continuous ultrafine fibers from various polymers and composites. The use of conductive polymer-based ultrafine fibers has great potential in applications such as bio/chemical sensors, artificial muscles, and tissue regeneration.
PROGRESS IN MATERIALS SCIENCE
(2021)
Article
Polymer Science
Kristina Peranidze, Tatiana V. Safronova, Nataliya R. Kildeeva
Summary: Currently, the field of tissue engineering is focused on developing polymer-based materials with suitable microenvironments for cell attachment, differentiation, and proliferation. The biomimicking approach aims to create biocompatible and bioactive materials that mimic the structural features of the natural extracellular matrix. This study discusses promising fibrous materials for bone tissue regeneration obtained through electrospinning techniques, including natural and synthetic polymers combined with bioactive inorganic materials.