Berberineviasuppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice

Vascular wall extracellular matrix proteins and vascular diseases

(2014) Junyan Xu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aberrant Endoplasmic Reticulum Stress in Vascular Smooth Muscle Increases Vascular Contractility and Blood Pressure in Mice Deficient of AMP-Activated Protein Kinase-α2 In Vivo

(2013) Bin Liang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Functional Role of TRPV4-K Ca 2.3 Signaling in Vascular Endothelial Cells in Normal and Streptozotocin-Induced Diabetic Rats

(2013) Xin Ma et al.   HYPERTENSION

TRPV4 channel activation leads to endothelium-dependent relaxation mediated by nitric oxide and endothelium-derived hyperpolarizing factor in rat pulmonary artery

(2013) Susanth V. Sukumaran et al.   PHARMACOLOGICAL RESEARCH

TRPV4 and the Regulation of Vascular Tone

(2012) Jessica A. Filosa et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca2+ events, and IKCa channels, reducing arteriolar tone

(2012) P. Bagher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TRPV4 channel is a novel regulator of intracellular Ca2+ in human esophageal epithelial cells

(2011) Takashi Ueda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Splice Variant Specific Modulation of Ca V 1.2 Calcium Channel by Galectin-1 Regulates Arterial Constriction

(2011) Juejin Wang et al.   CIRCULATION RESEARCH

Inhibition of the AMP-Activated Protein Kinase-α2 Accentuates Agonist-Induced Vascular Smooth Muscle Contraction and High Blood Pressure in Mice

(2011) Shuangxi Wang et al.   HYPERTENSION

Activation of AMP-Activated Protein Kinase Is Required for Berberine-Induced Reduction of Atherosclerosis in Mice: The Role of Uncoupling Protein 2

(2011) Qilong Wang et al.   PLoS One

CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity

(2010) Min-you Qi et al.   ACTA PHARMACOLOGICA SINICA

AMPKα2 Deletion Causes Aberrant Expression and Activation of NAD(P)H Oxidase and Consequent Endothelial Dysfunction In Vivo

(2010) Shuangxi Wang et al.   CIRCULATION RESEARCH

Redox Regulation of the AMP-Activated Protein Kinase

(2010) Yingying Han et al.   PLoS One

Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase

(2009) Yiqun Wang et al.   CARDIOVASCULAR RESEARCH

Transient Receptor Potential Vanilloid Type 4–Deficient Mice Exhibit Impaired Endothelium-Dependent Relaxation Induced by Acetylcholine In Vitro and In Vivo

(2009) David X. Zhang et al.   HYPERTENSION

The vanilloid transient receptor potential channel TRPV4: From structure to disease

(2009) Wouter Everaerts et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Na+/H+ exchanger is required for hyperglycaemia-induced endothelial dysfunction via calcium-dependent calpain

(2008) S. Wang et al.   CARDIOVASCULAR RESEARCH

Endothelium-Specific GTP Cyclohydrolase I Overexpression Attenuates Blood Pressure Progression in Salt-Sensitive Low-Renin Hypertension

(2008) Yan-Hua Du et al.   CIRCULATION

Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells

(2008) Kae-Woei Liang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY