High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression

Syndecan-1-Dependent Suppression of PDK1/Akt/Bad Signaling by Docosahexaenoic Acid Induces Apoptosis in Prostate Cancer

(2015) Yunping Hu et al.   NEOPLASIA

Endothelial cells respond to hyperglycemia by increasing the LPL transporter GPIHBP1

(2014) Amy Pei-Ling Chiu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glycosaminoglycans, Hyperglycemia, and Disease

(2013) Linda M. Hiebert et al.   ANTIOXIDANTS & REDOX SIGNALING

Alteration of endothelial proteoglycan and heparanase gene expression by high glucose, insulin and heparin

(2013) J. Han et al.   VASCULAR PHARMACOLOGY

Heparanase and Autoimmune Diabetes

(2013) Charmaine J. Simeonovic et al.   Frontiers in Immunology

Epidermal growth factor receptor expression and signaling are essential in glutamine's cytoprotective mechanism in heat-stressed intestinal epithelial-6 cells

(2012) Stefanie Niederlechner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Diabetes Mellitus and the Incidence of Colorectal Cancer: An Updated Systematic Review and Meta-Analysis

(2012) Longying Deng et al.   DIGESTIVE DISEASES AND SCIENCES

Heparanase Enhances the Insulin Receptor Signaling Pathway to Activate Extracellular Signal-regulated Kinase in Multiple Myeloma

(2012) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparanase Affects Food Intake and Regulates Energy Balance in Mice

(2012) Linda Karlsson-Lindahl et al.   PLoS One

An Artificial miRNA against HPSE Suppresses Melanoma Invasion Properties, Correlating with a Down-Regulation of Chemokines and MAPK Phosphorylation

(2012) Xiaoyan Liu et al.   PLoS One

Heparanase enhances nerve-growth-factor-induced PC12 cell neuritogenesis via the p38 MAPK pathway

(2011) Hengxiang Cui et al.   BIOCHEMICAL JOURNAL

Shedding of syndecan-1 from human hepatocytes alters very low density lipoprotein clearance

(2011) Yiping Deng et al.   HEPATOLOGY

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

(2011) Immanuel Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

Leaky gut and diabetes mellitus: what is the link?

(2011) S. de Kort et al.   Obesity Reviews

The Role of the p38 MAPK Signaling Pathway in High Glucose-Induced Epithelial-Mesenchymal Transition of Cultured Human Renal Tubular Epithelial Cells

(2011) Zhi-Mei Lv et al.   PLoS One

Proteoglycans in health and disease: the multiple roles of syndecan shedding

(2010) Tina Manon-Jensen et al.   FEBS Journal

A Role for Syndecan-1 and Claudin-2 in Microbial Translocation During HIV-1 Infection

(2010) Anthony J Smith et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Diabetes in Asia

(2009) Juliana C. N. Chan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function

(2008) Lars Bode et al.   JOURNAL OF CLINICAL INVESTIGATION