GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells

Injury Induces Direct Lineage Segregation of Functionally Distinct Airway Basal Stem/Progenitor Cell Subpopulations

(2015) Ana Pardo-Saganta et al.   Cell Stem Cell

A Grhl2-dependent gene network controls trophoblast branching morphogenesis

(2015) K. Walentin et al.   DEVELOPMENT

Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors

(2015) M. Mori et al.   DEVELOPMENT

A Grainyhead-Like 2/Ovo-Like 2 Pathway Regulates Renal Epithelial Barrier Function and Lumen Expansion

(2015) A. Aue et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Clonal Dynamics Reveal Two Distinct Populations of Basal Cells in Slow-Turnover Airway Epithelium

(2015) Julie K. Watson et al.   Cell Reports

Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung

(2015) Henry Danahay et al.   Cell Reports

Mutations in GRHL2 Result in an Autosomal-Recessive Ectodermal Dysplasia Syndrome

(2014) Gabriela Petrof et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Breaking Barriers. New Insights into Airway Epithelial Barrier Function in Health and Disease

(2014) Fariba Rezaee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

(2014) Brigid L.M. Hogan et al.   Cell Stem Cell

Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling

(2014) Manash K. Paul et al.   Cell Stem Cell

Modeling human development in 3D culture

(2014) Marius Ader et al.   CURRENT OPINION IN CELL BIOLOGY

Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells

(2014) R. J. Huebner et al.   DEVELOPMENT

Yap Tunes Airway Epithelial Size and Architecture by Regulating the Identity, Maintenance, and Self-Renewal of Stem Cells

(2014) Rui Zhao et al.   DEVELOPMENTAL CELL

ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes

(2014) Lisa D. Boxer et al.   GENES & DEVELOPMENT

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells

(2014) T. Tadokoro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

EGFR signaling promotes self-renewal through the establishment of cell polarity in Drosophila follicle stem cells

(2014) Angela Castanieto et al.   eLife

Architectural Niche Organization by LHX2 Is Linked to Hair Follicle Stem Cell Function

(2013) Alicia R. Folgueras et al.   Cell Stem Cell

Dedifferentiation of committed epithelial cells into stem cells in vivo

(2013) Purushothama Rao Tata et al.   NATURE

FRAP Analysis Reveals Stabilization of Adhesion Structures in the Epidermis Compared to Cultured Keratinocytes

(2013) Henry P. Foote et al.   PLoS One

Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium

(2013) Xia Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

ZNF750 Is a p63 Target Gene that Induces KLF4 to Drive Terminal Epidermal Differentiation

(2012) George L. Sen et al.   DEVELOPMENTAL CELL

On the biomechanics of stem cell niche formation in the gut - modelling growing organoids

(2012) Peter Buske et al.   FEBS Journal

Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25

(2012) Kazunori Senga et al.   MOLECULAR BIOLOGY OF THE CELL

The Functions of Grainy Head-Like Proteins in Animals and Fungi and the Evolution of Apical Extracellular Barriers

(2012) Adam Paré et al.   PLoS One

ZNF750 Is Expressed in Differentiated Keratinocytes and Regulates Epidermal Late Differentiation Genes

(2012) Idan Cohen et al.   PLoS One

Notch-Dependent Differentiation of Adult Airway Basal Stem Cells

(2011) Jason R. Rock et al.   Cell Stem Cell

Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion

(2011) Christina Pyrgaki et al.   DEVELOPMENTAL BIOLOGY

Epithelial cells and airway diseases

(2011) David Proud et al.   IMMUNOLOGICAL REVIEWS

The sentinel role of the airway epithelium in asthma pathogenesis

(2011) Stephen T. Holgate   IMMUNOLOGICAL REVIEWS

Distinct stem cells contribute to mammary gland development and maintenance

(2011) Alexandra Van Keymeulen et al.   NATURE

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex

(2010) M. Werth et al.   DEVELOPMENT

Regional neural tube closure defined by the Grainy head-like transcription factors

(2010) Yeliz Rifat et al.   DEVELOPMENTAL BIOLOGY

Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

(2010) John T. Connelly et al.   NATURE CELL BIOLOGY

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

(2008) Aron B. Jaffe et al.   JOURNAL OF CELL BIOLOGY