AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation

Cellular context–mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis

(2015) Monica Hellesøy et al.   MOLECULAR BIOLOGY OF THE CELL

Akt1 Activity Regulates Vessel Maturation in a Tissue Engineering Model of Angiogenesis

(2014) Monica Hellesøy et al.   TISSUE ENGINEERING PART A

PDK1 regulates platelet activation and arterial thrombosis

(2013) X. Chen et al.   BLOOD

Acquisition of epithelial–mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance

(2013) L Chang et al.   Cell Death & Disease

Akt kinase-interacting protein1, a novel therapeutic target for lung cancer with EGFR-activating and gatekeeper mutations

(2012) T Yamada et al.   ONCOGENE

Targeting PDK1 in Cancer

(2011) C. Raimondi et al.   CURRENT MEDICINAL CHEMISTRY

Phosphatidylserine is a critical modulator for Akt activation

(2011) Bill X. Huang et al.   JOURNAL OF CELL BIOLOGY

Atelocollagen-mediated Systemic Delivery Prevents Immunostimulatory Adverse Effects of siRNA in Mammals

(2011) Shinichiro Inaba et al.   MOLECULAR THERAPY

Anti-apoptosis and cell survival: A review

(2010) Liam Portt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Non-ATP Competitive Protein Kinase Inhibitors

(2010) L. Garuti et al.   CURRENT MEDICINAL CHEMISTRY

Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation

(2010) Zai Chang et al.   DEVELOPMENTAL BIOLOGY

ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish

(2010) Bin Ren et al.   JOURNAL OF CLINICAL INVESTIGATION

PDK1 Regulates Vascular Remodeling and Promotes Epithelial-Mesenchymal Transition in Cardiac Development

(2010) Q. Feng et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular Pharmacology and Antitumor Activity of PHT-427, a Novel Akt/Phosphatidylinositide-Dependent Protein Kinase 1 Pleckstrin Homology Domain Inhibitor

(2010) E. J. Meuillet et al.   MOLECULAR CANCER THERAPEUTICS

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Interleukin-33 induces angiogenesis and vascular permeability through ST2/TRAF6-mediated endothelial nitric oxide production

(2009) Y.-S. Choi et al.   BLOOD

Molecular Determinants of Grb14-Mediated Inhibition of Insulin Signaling

(2009) Diana Goenaga et al.   MOLECULAR ENDOCRINOLOGY

Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis

(2009) P Bonifazi et al.   Mucosal Immunology

A mechanosensitive transcriptional mechanism that controls angiogenesis

(2009) Akiko Mammoto et al.   NATURE

Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis

(2009) Kip M Connor et al.   Nature Protocols

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective Inhibition of Retinal Angiogenesis by Targeting PI3 Kinase

(2009) Yolanda Alvarez et al.   PLoS One

Endothelial progenitor cell homing: prominent role of the IGF2-IGF2R-PLC 2 axis

(2008) Y.-S. Maeng et al.   BLOOD

Freud-1/Aki1, a Novel PDK1-Interacting Protein, Functions as a Scaffold To Activate the PDK1/Akt Pathway in Epidermal Growth Factor Signaling

(2008) A. Nakamura et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance

(2008) J. R. Bayascas et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin

(2008) Tomoya Kitamura et al.   NATURE CELL BIOLOGY

PI3K/PTEN signaling in tumorigenesis and angiogenesis

(2007) Bing-Hua Jiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS