Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness

Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis

(2015) Julia R. Kardon et al.   CELL

The structure of the human mitochondrial ribosome

(2015) A. Amunts et al.   SCIENCE

The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease

(2014) Angelika B. Harbauer et al.   Cell Metabolism

Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics

(2014) M. J. Baker et al.   EMBO JOURNAL

Thei-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

(2014) Ruchika Anand et al.   JOURNAL OF CELL BIOLOGY

Structure of the large ribosomal subunit from human mitochondria

(2014) A. Brown et al.   SCIENCE

A Mitochondrial Ribosomal and RNA Decay Pathway Blocks Cell Proliferation

(2013) Uwe Richter et al.   CURRENT BIOLOGY

Why translation counts for mitochondria - retrograde signalling links mitochondrial protein synthesis to mitochondrial biogenesis and cell proliferation

(2013) B. J. Battersby et al.   JOURNAL OF CELL SCIENCE

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

Architecture of the large subunit of the mammalian mitochondrial ribosome

(2013) Basil J. Greber et al.   NATURE

Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65

(2013) Hiroyuki Kogure et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

(2012) Pedro M Quirós et al.   EMBO JOURNAL

Unusual and Typical Features of a Novel Restorer-of-Fertility Gene of Sugar Beet ( Beta vulgaris L.)

(2012) Hiroaki Matsuhira et al.   GENETICS

Mitochondrial Protein Synthesis, Import, and Assembly

(2012) Thomas D. Fox   GENETICS

Respiratory dysfunction by AFG3L2 deficiency causes decreased mitochondrial calcium uptake via organellar network fragmentation

(2012) F. Maltecca et al.   HUMAN MOLECULAR GENETICS

Oligomerization of HemeoSynthase in Cytochrome Oxidase Biogenesis Is Mediated by Cytochrome Oxidase Assembly Factor Coa2

(2012) Oleh Khalimonchuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution and Diversification of the Organellar Release Factor Family

(2012) Isabel Duarte et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mechanism of protein biosynthesis in mammalian mitochondria

(2011) Brooke E. Christian et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Turnover of ATP synthase subunits in F1-depleted HeLa and yeast cells

(2011) Malgorzata Rak et al.   FEBS LETTERS

Unfolded protein responses in bacteria and mitochondria: A central role for the ClpXP machine

(2011) Kaye N. Truscott et al.   IUBMB LIFE

Interplay Between N-Terminal Methionine Excision and FtsH Protease Is Essential for Normal Chloroplast Development and Function in Arabidopsis

(2011) Z. Adam et al.   PLANT CELL

Quality Control of Mitochondrial Proteostasis

(2011) M. J. Baker et al.   Cold Spring Harbor Perspectives in Biology

Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis

(2011) Sonia Fieulaine et al.   PLOS BIOLOGY

Mutations in C12orf65 in Patients with Encephalomyopathy and a Mitochondrial Translation Defect

(2010) Hana Antonicka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Current Views of the Structure of the Mammalian Mitochondrial Ribosome

(2010) Emine C. Koc et al.   ISRAEL JOURNAL OF CHEMISTRY

Solution Structure of the Catalytic Domain of the Mitochondrial Protein ICT1 That Is Essential for Cell Vitality

(2010) Yoshihiro Handa et al.   JOURNAL OF MOLECULAR BIOLOGY

Inhibition of Human Peptide Deformylase Disrupts Mitochondrial Function

(2010) S. Escobar-Alvarez et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Methylation of 12S rRNA Is Necessary for In Vivo Stability of the Small Subunit of the Mammalian Mitochondrial Ribosome

(2009) Metodi D. Metodiev et al.   Cell Metabolism

Genetic interaction between the m -AAA protease isoenzymes reveals novel roles in cerebellar degeneration

(2009) Paola Martinelli et al.   HUMAN MOLECULAR GENETICS

Regulation of OPA1 processing and mitochondrial fusion bym-AAA protease isoenzymes and OMA1

(2009) Sarah Ehses et al.   JOURNAL OF CELL BIOLOGY

Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells

(2009) Brian Head et al.   JOURNAL OF CELL BIOLOGY

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL

The A3243G tRNALeu(UUR) MELAS mutation causes amino acid misincorporation and a combined respiratory chain assembly defect partially suppressed by overexpression of EFTu and EFG2

(2008) F. Sasarman et al.   HUMAN MOLECULAR GENETICS

Coordination of gene expression between organellar and nuclear genomes

(2008) Jesse D. Woodson et al.   NATURE REVIEWS GENETICS