Article
Chemistry, Analytical
Yuliang Zhao, Hongyu Zhang, Yang Li, Xiaoai Wang, Liang Zhao, Jianghong Xu, Zhikun Zhan, Guanglie Zhang, Wen Jung Li
Summary: An electrochemical HbA1c sensor with high sensitivity and good specificity is proposed, which is based on the electrochemical immune principle. The sensor's properties were characterized and analyzed, and the experimental results demonstrated its satisfactory performance in terms of detection limit, sensitivity, repeatability, stability, and anti-interference capabilities.
Article
Chemistry, Analytical
V. Sunil Kumar, Shekher Kummari, Gaelle Catanante, K. Vengatajalabathy Gobi, Jean Louis Marty, K. Yugender Goud
Summary: A label-free electrochemical impedimetric immunosensor was developed for rapid and sensitive detection of zearalenone (ZEN) using palladium nanoparticle embedded functionalized carbon nanotube-chitosan (SPCE/CS-CNT-Pd) modified electrode. The structure of the nanocomposite was analyzed and verified using X-ray diffraction, transmission electron microscopy, and energy dispersive X-ray spectroscopy. The coexistence of Pd nanoparticles with CNTs enhanced the conductivity and catalytic properties of the transducer surface, as well as improved antibody immobilization. The immunosensor showed high sensitivity and simplicity compared to conventional methods and successfully detected ZEN in corn samples with good recovery values.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Melinda David, Adrian Serban, Teodor Adrian Enache, Monica Florescu
Summary: This study described and compared the performances of commercial screen-printed carbon electrodes with different nanostructured materials for LT4 detection. The presence of carbon nanotubes resulted in the best performance for LT4 detection.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Ping-Ghun Wang, Bor-Ran Li, Yu-Lin Wang, Ching-Chou Wu, Jung-Chih Chen
Summary: Alzheimer's disease is an important neurodegenerative disease in the aging society, with beta-amyloid being a crucial factor in its development. This research focuses on developing an immunosensor using an electrochemical system and screen-printed carbon electrode to detect beta-amyloid. The study optimizes the electrodeposition conditions and tests the sensor's specificity, achieving a labelfree and low-cost immunosensor with high stability and a wide range of detection.
Article
Electrochemistry
Ping Liu, Xingpu Qi, Huanxin Zhang, Yi Zheng
Summary: This study presented the preparation of a sensitive electrochemical immunosensor to detect Aflatoxin B1 (AFB1) and demonstrated its reliability and accuracy in determining AFB1 in real maize samples. The immunosensor exhibited stable and sensitive electrochemical responses, with comparable or better performance compared to other reported AFB1 immunosensors in the literature. The results also showed that the immunosensor had acceptable recovery and relative standard deviation values, confirming its practical utility in real sample analysis.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2021)
Article
Electrochemistry
Wichayaporn Kamsong, Vitsarut Primpray, Patiya Pasakon, Chakrit Sriprachuabwong, Saithip Pakapongpan, Johannes Philipp Mensing, Anurat Wisitsoraat, Adisorn Tuantranont, Chanpen Karuwan
Summary: A highly sensitive and disposable screen-printed ionic liquid-graphene electrode (SPIL-GE) was developed for electrochemical sensing. The electrode showed improved electrochemical performance compared to other types of electrodes, making it a potential candidate for advanced electrochemical sensing applications.
ELECTROCHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
Gozde Kabay, Yaoqi Yin, Chandra K. Singh, Nihal Ahmad, Sundaram Gunasekaran, Mehmet Mutlu
Summary: Prostate cancer is the second most common cancer among men worldwide, and early and accurate diagnosis is crucial. To address this need, researchers have developed an electrochemical immunosensor for sensitive detection of the prostate-specific membrane antigen (PSMA). The sensor shows high analytical performance and can be used for detection in body fluids.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Biophysics
Paulo Roberto de Oliveira, Robert D. Crapnell, Alejandro Garcia -Miranda Ferrari, Phatsawit Wuamprakhon, Nicholas J. Hurst, Nina C. Dempsey-Hibbert, Montree Sawangphruk, Bruno Campos Janegitz, Craig E. Banks
Summary: This manuscript presents a design for screen-printed arrays (SPAs) for the determination of raised levels of serum procalcitonin (PCT). The SPAs showed good reproducibility and were modified with antibodies specific for PCT detection. The platform achieved a linear dynamic range and had the potential for rapid testing in specific patient populations.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Hayati Filik, Asiye Aslihan Avan, Nilay Altas Puntar, Mustafa Ozyurek, Zeynep Banu Gungor, Mine Kucur, Handan Kamis, Diclehan Ali Dicle
Summary: A sensitive sandwich-model immunoassay was designed for simultaneous electrochemical measurement of alphafetoprotein and carcinoembryonic antigen using multiple-label strategy. The immunoassay showed good linear relationship and low detection limits for both analytes. The sandwich-type immunosensor was successfully applied to real serum sample analysis.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Biotechnology & Applied Microbiology
Nan Wang, Guiying Pan, Shimin Guan, Shaofeng Rong, Dapeng Wang, Zhiyong Gao, Peng Tian, Qianqian Li
Summary: In this study, an electrochemical biosensor based on a screen-printed carbon electrode was developed for the rapid detection of human noroviruses (HuNoVs). The biosensor showed high sensitivity and specificity, and could detect different genogroups and genotypes of HuNoVs. The detection limit of HuNoVs in clinical fecal samples was 10(4) genomic copies/mL. The results could be obtained within 1 hour.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Analytical
Jiaqi Gao, Zhongqiu Hua, Shu Xu, Hao Wan, Zinan Zhi, Xinyi Chen, Shurui Fan
Summary: An amperometric gas sensor using room temperature ionic liquid electrolyte and screen-printed electrodes was developed in this study. The sensor demonstrated rapid response speed, high sensitivity, and wide operating temperature range, making it suitable for use in extreme environments.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Danilo Echeverri, Jahir Orozco
Summary: This study reports an electrochemical immunosensor for the detection of the novel beta-1,4-GalT-V CRC biomarker. The immunosensor covalently couples an anti-beta-1,4-GalT-V antibody on a self-assembled monolayer-coated gold electrode surface and shows high specificity in capturing the beta-1,4-GalT-V glycoprotein from human serum samples. The response of the immunosensor, monitored by electrochemical impedance spectroscopy, is protein concentration-dependent.
Article
Multidisciplinary Sciences
Hassan A. Alhazmi, Waquar Ahsan, Manal M. E. Taha, Mohammed Albratty, Asim Najmi, Abdullah Farasani, Ahmed A. Abdulhaq, Ibrahim A. Darwish
Summary: This study developed a cost-effective and sensitive immunosensor for rapid detection of dengue virus (DENV) antigen in human plasma. The immunosensor was fabricated using screen-printed carbon electrodes (SPCEs) and the antigen-antibody interaction was detected using linear sweep voltammetry (LSV). The developed immunosensor showed excellent sensitivity and could detect the DENV antigen in both phosphate buffer saline (PBS) and human plasma, with a rapid detection time of 5 min.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Chemistry, Analytical
Sergio Lucas-Sanchez, Lucia Abad-Gil, Carmen Isabel-Cabrera, M. Jesus Gismera, M. Teresa Sevilla, Jesus R. Procopio
Summary: This study presents an HPLC method with electrochemical detection using disposable screen-printed electrodes (SPE) for simultaneous determination of 6 different parabens in personal care products. The electrochemical behavior of parabens was studied on different carbon-based materials, and the most suitable conditions were chosen. A fast ultrasound-assisted extraction method was applied to extract the parabens from complex-matrix cosmetic products. The proposed method is versatile, fast, and has been successfully applied to commercial samples.
Article
Chemistry, Physical
Ebrar Dokur, Selen Uruc, Rabianur Kurteli, Ozge Gorduk, Yucel Sahin
Summary: This study presents an improved handmade screen-printed electrode (SPE) that can be easily produced using conductive ink. The electrode is based on a cardboard substrate and is used as an electrochemical sensor. The alkaline pretreatment applied to the cardboard substrate is reported for the first time in the literature. The electrode is characterized using various techniques and is successfully used for the determination of dopamine.
Article
Physics, Applied
Jinwang Li, Hirokazu Tsukada, Takaaki Miyasako, Phan Trong Tue, Kazuhiro Akiyama, Hiromi Nakazawa, Yuzuru Takamura, Tadaoki Mitani, Tatsuya Shimoda
JOURNAL OF APPLIED PHYSICS
(2020)
Article
Chemistry, Analytical
Kenta Mizuna, Ryo Murashima, Takuya Okazaki, Kazuto Sazawa, Hideki Kuramitz, Shigeru Taguchi, Keiko Nakayama, Tamotsu Yamamoto, Yuzuru Takamura, Noriko Hata
ANALYTICAL SCIENCES
(2020)
Article
Chemistry, Analytical
Masahiko Yamamoto, Van-Khoai Do, Shigeo Taguchi, Takehiko Kuno, Yuzuru Takamura
Summary: A simple and reliable analytical method using LEP-OES was developed for determination of Na, K, Ca, Sr, and Ba in radioactive waste, with investigation on emission lines, interference from co-existing elements, and adjustment of nitric acid concentration. Spike and recovery tests showed negligible sample matrix effect, with data matching with ORIGEN code and inductively coupled plasma optical emission spectrometry within 10% difference, demonstrating successful application to real radioactive wastes.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2021)
Article
Chemistry, Analytical
Suman Barua, Ismail M. M. Rahman, Maho Miyaguchi, Kouki Yunoshita, Prasongporn Ruengpirasiri, Yuzuru Takamura, Asami S. Mashio, Hiroshi Hasegawa
MICROCHEMICAL JOURNAL
(2020)
Article
Multidisciplinary Sciences
Shinichi Hashimoto, Takayoshi Shirasaki, Taro Yamashita, Sadahiro Iwabuchi, Yutaka Suzuki, Yuzuru Takamura, Yoshiaki Ukita, Shungo Deshimaru, Toshitugu Okayama, Kazuho Ikeo, Kazuyuki Kuroki, Kazunori Kawaguchi, Eishiro Mizukoshi, Kouji Matsushima, Masao Honda, Shuichi Kaneko
Summary: Using single-cell RNA sequencing analysis, four genes including DOCK11 and DENND2A were identified to be linked to the maintenance of HBV in liver cells. Knockdown of these genes in primary human hepatocytes infected with HBV resulted in a decrease in both HBV DNA and covalently closed circular DNA. This study reveals a role for DOCK11 and DENND2A in maintaining HBV in a latent state.
Article
Chemistry, Multidisciplinary
Hirotaka Uzawa, Satoshi Kondo, Takehiro Nagatsuka, Hajime Miyaguchi, Yasuo Seto, Aguri Oshita, Hirofumi Dohi, Yoshihiro Nishida, Masato Saito, Eiichi Tamiya
Summary: The microwave irradiation effectively promotes the installing process for three different GSL derivatives, with each requiring a different optimal thermal condition. The study utilized a localized surface plasmon resonance biosensor to analyze the enhanced response of these GSL glycochips to corresponding toxins.
Article
Chemistry, Analytical
Yueh-Han Huang, Daisuke Hirose, Jun Minami, Meng-Jiy Wang, Yuzuru Takamura
Summary: This study successfully proposed and fabricated an axial view liquid electrode plasma-atomic emission spectrometry, which demonstrated better sensing ability towards trace heavy metals. By utilizing pulsed voltage discharge and optimized parameters, the detection limit was significantly improved.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Sumamal Charernchai, Miyuki Chikae, Tue Trong Phan, Wanida Wonsawat, Daisuke Hirose, Yuzuru Takamura
Summary: This study reports a microfluidic paper-based analytical device for automating the competitive enzyme-linked immunosorbent assay. This device offers high sensitivity, small sample volume, equipment-free measurements, low-cost operation, and user-friendliness. The method developed in this study can be used for small molecule analysis in fields such as food safety and quality control, environmental monitoring, and clinical diagnostics.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Eiichi Tamiya
Summary: This paper introduces portable sensors based on genetic measurements for diagnosing infectious diseases and disease risk using SNPs. The sensors utilize electrochemical measurements with printed electrodes to detect changes in nucleic acid-binding molecules and monitor the amplification of specific genes. The method has been successfully applied to measure pathogenic microorganisms and viruses, as well as diagnose SNPs related to Alzheimer's disease.
Article
Chemistry, Analytical
Eiichi Tamiya, Shuto Osaki, Tomoko Tsuchihashi, Hiromi Ushijima, Keiichi Tsukinoki
Summary: Monitoring biomarkers using saliva instead of blood samples is advantageous for assessing daily physical condition. This study analyzed the levels of neutralizing antibodies, IgG, and sIgA in response to the SARS-CoV-2 vaccine in saliva. Results showed increased salivary IgG levels after the second vaccination, along with an increasing trend in sIgA levels. This suggests the potential for using saliva to routinely assess vaccine efficacy. The development of an electrochemical immunosensor assay using portable devices offers a useful tool for individual-based diagnosis using saliva samples.
Article
Chemistry, Multidisciplinary
Hirotaka Uzawa, Takehiro Nagatsuka, Yasuo Seto, Yoshihiro Nishida, Masato Saito, Eiichi Tamiya
Summary: Glycolipid chips with a double layer of Au nanoparticles were developed for detecting biological toxins. The chips consisted of an under and an upper layer of Au nanoparticles on glass plates, linked with 1,8-octanedithiol using a self-assembled monolayer technique. A tris-sialo glycosphingolipid, ganglioside GT1b, was immobilized on the upper layer and botulinum toxin was detected using localized surface plasmon resonance (LSPR). The GT1bCer-coated chip with a double layer of Au nanoparticles showed enhanced LSPR detection of the toxin compared to single monolayers. The combination of 60 and 40 nm Au nanoparticles in the under and upper layer, respectively, achieved the best results for toxin detection below 5 ng/mL using a portable LSPR device.
Article
Biochemical Research Methods
Hiroki Shigemori, Satoshi Fujita, Eiichi Tamiya, Shin-ichi Wakida, Hidenori Nagai
Summary: The CRISPR/Cas12 system has potential as a next-generation nucleic acid detection tool. A solid-phase collateral cleavage (SPCC) reaction is utilized to achieve one-pot multiplex dsDNA detection with minimal operational steps. The sensor immobilizes Cas12-crRNA and ssDNA on the sensing surface and demonstrates high sequence specificity and sensitivity.
BIOCONJUGATE CHEMISTRY
(2023)
Article
Physics, Applied
Hiromi Nakazawa, Hiroshi Ishii, Yuzuru Takamura
Summary: All-solid-state electric double-layer (EDL) thin-film transistors (TFTs) with LaZrO gate insulators and sputtered InO channels were studied. The transfer conductance of the TFTs increased with the thickness of the InO layer and reached a maximum at 200 nm. The capacitance of LaZrO indicated the formation of an EDL. The mobility of the TFTs also increased with the InO thickness and was affected by grain boundary and surface scattering.
JOURNAL OF APPLIED PHYSICS
(2023)
Article
Chemistry, Analytical
Yuhei Terada, Ain Obara, Jonathan Campos Briones, Xi Luo, Wilfred Villariza Espulgar, Masato Saito, Hyota Takamatsu, Eiichi Tamiya
Summary: Single-cell analysis is increasingly important for revealing cell heterogeneity, with implications in medicine and biology. The development of a single-cell secretion detection chip with microwells and Au nanopillars for localized surface plasmon resonance (LSPR) measurement represents a significant advancement in cell biology and immunology. The chip allows for the direct detection of IL-6 secretion from individual cells and achieves a high trapping efficiency of over 80%.
Article
Nanoscience & Nanotechnology
Yuhei Terada, Ain Obara, Hyota Takamatsu, Wilfred Villariza Espulgar, Masato Saito, Eiichi Tamiya
Summary: The thickness of the biomolecular layer on the Au surface was controlled by changing the polymer chain length of the immobilized glycopolymer, and the absorption of proteins onto the Au surface was detected by the shift of absorbance peak wavelength. This difference in LSPR signal response was remarkable for cytokine recognition compared to larger proteins.
ACS APPLIED BIO MATERIALS
(2021)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)