Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression

Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival

(2014) Alexandra N. Elsing et al.   JOURNAL OF CELL BIOLOGY

Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition

(2013) Anna Budina-Kolomets et al.   CANCER BIOLOGY & THERAPY

The HSP70 family and cancer

(2013) M. E. Murphy   CARCINOGENESIS

Coordination of adjacent domains mediates TACC3–ch-TOG–clathrin assembly and mitotic spindle binding

(2013) Fiona E. Hood et al.   JOURNAL OF CELL BIOLOGY

A Modified HSP70 Inhibitor Shows Broad Activity as an Anticancer Agent

(2013) Gregor M. Balaburski et al.   MOLECULAR CANCER RESEARCH

Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?

(2012) L. Neckers et al.   CLINICAL CANCER RESEARCH

Cell cycle regulation by the NEK family of protein kinases

(2012) A. M. Fry et al.   JOURNAL OF CELL SCIENCE

Peptides and Aptamers Targeting HSP70: A Novel Approach for Anticancer Chemotherapy

(2011) Anne-Laure Rérole et al.   CANCER RESEARCH

Targeting HSP70: The second potentially druggable heat shock protein and molecular chaperone?

(2011) Marissa V. Powers et al.   CELL CYCLE

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

(2011) Daniel G Booth et al.   EMBO JOURNAL

Nek family of kinases in cell cycle, checkpoint control and cancer

(2011) Larissa Moniz et al.   Cell Division

Targeting heat shock proteins in cancer

(2010) Gaëtan Jego et al.   CANCER LETTERS

Characterization of hNek6 Interactome Reveals an Important Role for Its Short N-Terminal Domain and Colocalization with Proteins at the Centrosome

(2010) Gabriela Vaz Meirelles et al.   JOURNAL OF PROTEOME RESEARCH

Nek6 Mediates Human Cancer Cell Transformation and Is a Potential Cancer Therapeutic Target

(2010) Rounak Nassirpour et al.   MOLECULAR CANCER RESEARCH

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells

(2009) Andrew J. Massey et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Pharmacological Targeting of the Hsp70 Chaperone

(2009) Srikanth Patury et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis

(2009) L. O'Regan et al.   MOLECULAR AND CELLULAR BIOLOGY

An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9

(2009) Mark W. Richards et al.   MOLECULAR CELL

A Small Molecule Inhibitor of Inducible Heat Shock Protein 70

(2009) J. I-Ju Leu et al.   MOLECULAR CELL

Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis

(2008) A Takeno et al.   BRITISH JOURNAL OF CANCER

Dual Targeting of HSC70 and HSP72 Inhibits HSP90 Function and Induces Tumor-Specific Apoptosis

(2008) Marissa V. Powers et al.   CANCER CELL

The NIMA-family kinase Nek6 phosphorylates the kinesin Eg5 at a novel site necessary for mitotic spindle formation

(2008) J. Rapley et al.   JOURNAL OF CELL SCIENCE