期刊
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
卷 9, 期 4, 页码 481-498出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s10237-010-0189-7
关键词
Cerebral aneurysms; Fluid-structure interaction; Arterial wall tissue modeling; Incompressible Navier-Stokes equations; Boundary layer meshing; Wall shear stress; Wall tension; Tissue prestress
资金
- Teragrid [MCAD7S032]
- regional health authorities in northern Norway
A computational vascular fluid-structure interaction framework for the simulation of patient-specific cerebral aneurysm configurations is presented. A new approach for the computation of the blood vessel tissue prestress is also described. Simulations of four patient-specific models are carried out, and quantities of hemodynamic interest such as wall shear stress and wall tension are studied to examine the relevance of fluid-structure interaction modeling when compared to the rigid arterial wall assumption. We demonstrate that flexible wall modeling plays an important role in accurate prediction of patient-specific hemodynamics. Discussion of the clinical relevance of our methods and results is provided.
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