Next-generation, genome sequencing-based biomarkers: concerns and challenges for medical practice

Benefits and Harms of Prostate-Specific Antigen Screening for Prostate Cancer: An Evidence Update for the U.S. Preventive Services Task Force

(2013) Kenneth Lin et al.   ANNALS OF INTERNAL MEDICINE

From tumor size andHER2status to systems oncology for very early breast cancer treatment

(2010) Dimitrios H Roukos et al.   Expert Review of Anticancer Therapy

Bionetworks-based personalized medicine versus comparative-effectiveness research or harmonization of both in cancer management?

(2010) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Beyond HER2 and Trastuzumab: Heterogeneity, Systems Biology, and Cancer Origin Research May Guide the Future for Personalized Treatment of Very Early but Aggressive Breast Cancer

(2010) Dimitrios H. Roukos   JOURNAL OF CLINICAL ONCOLOGY

Parliament needs members who are scientifically literate

(2010) Stéphane Goldstein   NATURE

Human genome at ten: The sequence explosion

(2010)   NATURE

Point: Hypotheses first

(2010) Robert Weinberg   NATURE

The human genome at ten

(2010)   NATURE

Human genome at ten: Life is complicated

(2010) Erika Check Hayden   NATURE

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Big science: The cancer genome challenge

(2010) Heidi Ledford   NATURE

Multiple personal genomes await

(2010) J. Craig Venter   NATURE

Has the revolution arrived?

(2010) Francis Collins   NATURE

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Performance of Common Genetic Variants in Breast-Cancer Risk Models

(2010) Sholom Wacholder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systems medicine: a real approach for future personalized oncology?

(2010) Dimitrios H Roukos   PHARMACOGENOMICS

Breast Cancer Outcomes: The Crucial Role of the Breast Surgeon in the Era of Personal Genetics and Systems Biology

(2009) Dimitrios H. Roukos   ANNALS OF SURGERY

Genetics and Personal Genomics for Personalized Breast Cancer Surgery: Progress and Challenges in Research and Clinical Practice

(2009) Dimosthenis Ziogas et al.   ANNALS OF SURGICAL ONCOLOGY

Targeting Gastric Cancer with Trastuzumab: New Clinical Practice and Innovative Developments to Overcome Resistance

(2009) Dimitrios H. Roukos   ANNALS OF SURGICAL ONCOLOGY

Genome-wide association studies: how predictable is a person’s cancer risk?

(2009) Dimitrios H Roukos   Expert Review of Anticancer Therapy

Personalized cancer diagnostics and therapeutics

(2009) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Novel clinico–genome network modeling for revolutionizing genotype–phenotype-based personalized cancer care

(2009) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

Complex landscapes of somatic rearrangement in human breast cancer genomes

(2009) Philip J. Stephens et al.   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Personal Genomics and Genome-Wide Association Studies: Novel Discoveries but Limitations for Practical Personalized Medicine

(2008) Dimitrios H. Roukos   ANNALS OF SURGICAL ONCOLOGY

Use of Gene Signatures to Improve Risk Estimation in Cancer

(2008) Chiang-Ching Huang   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Reverse engineering the genotype–phenotype map with natural genetic variation

(2008) Matthew V. Rockman   NATURE

Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events

(2008) Sekar Kathiresan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE