期刊
BIOMARKERS
卷 16, 期 6, 页码 504-510出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/1354750X.2011.599042
关键词
fiber; inflammation; cytokine; chemokine; EPIC-Italy
资金
- HuGeF Foundation, Torino
- MRC [G0801056] Funding Source: UKRI
- Medical Research Council [G0801056, G0801056B] Funding Source: researchfish
Dietary fiber may modulate the environment of the intestinal lumen, alter the intestinal microflora populations, and influence the immune response and disease risk. Epidemiological investigations have suggested that higher fiber intake is associated with lower overall mortality, in particular from cardiovascular and digestive tract diseases. Here a panel of 17 cytokines and chemokines were measured in plasma of 88 cancer-free subjects sampled within the Italian EPIC-Italy cohort. A statistically significant inverse association (p-trend = 0.01) was observed for cereal fiber and cytokines included in the main factor in factor analysis (IL-1 beta, IL-4, IL-5, IL-6, IL-13, and TNF-alpha), which alone explained 35.5% of variance. Our study suggests that fiber intake, especially cereal fiber, may be associated with a decreased level of pro-inflammatory cytokines.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据