期刊
BIOMACROMOLECULES
卷 15, 期 6, 页码 2320-2325出版社
AMER CHEMICAL SOC
DOI: 10.1021/bm5005417
关键词
-
资金
- NSF [CHE-0924431]
Zwitterionic chitosan nanoparticles (ZCNPs) were conveniently obtained by a one-step aerosol method, and their potential for the production of biocompatible materials was investigated. A low-molecular-weight chitosan was conjugated with succinic anhydride to produce zwitterionic chitosan (ZC). Collisonatomized ZC droplets were simultaneously UV-irradiated and dried in a tube furnace in a one-step aerosol process to produce particles. The observed cytotoxicities of ZCNPs (85 +/- 3.9% cell viability) were similar to unmodified chitosan nanoparticles (CNPs, 88 +/- 6.6%) and UV-irradiated ZCNPs (83 +/- 3.3%). The aerosol process described in this work allowed facile production and modification of CNPs, which could then be employed for biomedical purposes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据