Article
Materials Science, Multidisciplinary
Chelsie L. Beck, Brian J. Riley, Saehwa Chong, Abhijeet Karkamkar, Derrick R. Seiner, Sue B. Clark
Summary: This study demonstrates the highly adsorptive nature of molecular iodine on stainless steel surfaces and provides evidence of metal iodide formation. By combining ICP-OES and EDS techniques, minor stainless-steel constituents including NiI2, MnI2 and CrI2 were identified in the metal iodide formation process.
JOURNAL OF NUCLEAR MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Hyun June Moon, Jan-Michael Carrillo, Johannes Leisen, Bobby G. Sumpter, Naresh C. Osti, Madhusudan Tyagi, Christopher W. Jones
Summary: This study investigates the effects of different interaction modes on the dynamics and structures of PEI in mesoporous materials and analyzes their relationship with CO2 adsorption performance. The results reveal that complex interfacial interactions result in complex structure-property relationships. The study also finds that macroscopic structures and PEI chain motions influence the rate of CO2 adsorption.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Applied
Hao Wu, Shuqian Hu, Chunling Nie, Jiahui Zhang, Huafeng Tian, Weicheng Hu, Ting Shen, Jianguo Wang
Summary: A novel method was described for synthesizing antibacterial cellulose beads, which exhibited excellent antimicrobial activity and biodegradability, showing great potential for use in food and environmental applications.
CARBOHYDRATE POLYMERS
(2021)
Review
Biotechnology & Applied Microbiology
Liang Wang, Chongyang Zhang, Jianhua Zhang, Zhiming Rao, Xueming Xu, Zhonggui Mao, Xusheng Chen
Summary: The review compares traditional and advanced strategies for discovering and cultivating high-producing strains of epsilon-poly-L-lysine, including traditional methods based on isolation and culture, genome mining, and directed evolution. Additionally, process engineering methods for improving production and efficient downstream purification methods are discussed in the article.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Sijin Chen, Shuting Huang, Yan Li, Chuncai Zhou
Summary: This review summarized the advanced development in the synthesis and modification strategies of ε-poly-L-lysine (EPL) and lysine-based dendrimer (LBD) compounds, focusing on their applications in biomedical fields such as agents, adjuvants, and carriers for anti-pathogen, tumor, and gene therapies. The combination with other advanced methodologies and technologies shows potential for overcoming challenges like scale production and high expenses in the future development of lysine-based polymers.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Physical
Tuuva Kastinen, Dawid Lupa, Piotr Bonarek, Dmitrii Fedorov, Maria Morga, Markus B. Linder, Jodie L. Lutkenhaus, Piotr Batys, Maria Sammalkorpi
Summary: We demonstrate that pH significantly affects the assembly mechanism and properties of PLL and PGA complexes through a combination of experimental characterization and molecular simulations. Various techniques, including DLS, LDV, ITC, CD, and AUC, are employed to assess the complexation, charge state, thermodynamics, secondary structure, and molecular weights of the peptides. Molecular dynamics simulations provide insights into the binding changes and hydrogen bonding involved in the complex formation. Our findings reveal the pH dependency of PLL/PGA complexation and highlight the potential of pH control in designing peptide materials.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Biotechnology & Applied Microbiology
Gavin Gonzales, Jiaul Hoque, Anna Gilpin, Biswanath Maity, Stefan Zauscher, Shyni Varghese
Summary: This study focuses on the development of cationic nanocarriers to overcome the challenges of drug delivery to cartilage tissue. These nanocarriers, which adhere quickly to cartilage tissue and can penetrate and remain within its full thickness, show promising results for therapeutic outcomes.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2023)
Article
Chemistry, Applied
Chunling Nie, Ting Shen, Weicheng Hu, Qin Ma, Jiahui Zhang, Shuqian Hu, Huafeng Tian, Hao Wu, Xiaogang Luo, Jianguo Wang
Summary: In this study, cellulose beads grafted with epsilon-poly-L-lysine were prepared through chemical reactions. The grafted beads showed strong antibacterial activities and biodegradability, indicating potential applications in water purification and food treatment fields.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Multidisciplinary
Jie Yu, Danwei Cen, Yongcheng Chen, Hailan Zhao, Mengyue Xu, Sulan Wu, Shuo Wang, Qiao Jin, Ting Shen
Summary: Antibiotic resistance poses a significant threat to public health, and improving the therapeutic efficacy of conventional antibiotics is an effective solution. By conjugating the positively charged epsilon-poly-l-lysine to erythromycin, the modified EPL-EM showed enhanced antibacterial activity and reduced drug resistance development. Furthermore, EPL-EM exhibited excellent biocompatibility without inducing hemolysis and cytotoxicity.
Article
Chemistry, Applied
Cong Wang, Hui Cao, Lingyun Jia, Wenli Liu, Pengtao Liu
Summary: This study designed an aerogel material using TOCNF/ε-PL network and citric acid as the cross-linking agent. Experimental results showed that the aerogel had good mechanical properties, antibacterial effects, biodegradability, and blood compatibility, indicating great potential applications in medical and food packaging fields.
CARBOHYDRATE POLYMERS
(2022)
Review
Engineering, Biomedical
Maochao Zheng, Miao Pan, Wancong Zhang, Huanchang Lin, Shenlang Wu, Chao Lu, Shijie Tang, Daojun Liu, Jianfeng Cai
Summary: Poly(alpha-L-lysine) (PLL) is a water-soluble, cationic biopolymer composed of alpha-L-lysine structural units. Over the past decade, significant progress has been made in the synthesis and biomedical applications of PLL, including antibacterial agents, gene/drug/protein delivery systems, bio-sensing, bio-imaging, and tissue engineering. Despite the promising potential of PLL-based nanomaterials in biomedical fields, challenges and perspectives still need to be addressed.
BIOACTIVE MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Almudena Marti, Jurriaan Huskens
Summary: Affinity sensing of nucleic acids is a highly investigated area in biosensing, and in this study, a simple electrochemical DNA detection layer is developed using poly-l-lysine and gold nanoparticles as a signal amplifier. The method shows high contrast and sensitivity, making it potentially useful in DNA diagnostics.
Article
Biotechnology & Applied Microbiology
Genan Wang, Jiaqian Li, Shuxian Wang, Yutong Li, Shiwei Chen, Lina Zhang, Tingbin Zhao, Haisong Yin, Shiru Jia, Changsheng Qiao
Summary: This study investigated the impact of different substrate concentrations and secondary indexes on PMLA production using machine learning methods, and achieved high accuracy prediction of PMLA production using a convolutional neural network model. Evaluated different substrate concentrations and the application of CNN model in the PMLA fermentation industry have important implications.
FERMENTATION-BASEL
(2022)
Article
Materials Science, Multidisciplinary
Fabien Granier, Sebastien Marie, Zahra Al Amir Dache, Julien Aityaya, Thibault Mazard, Laurent Garrelly, Corinne Prevostel
Summary: This study provides an in vitro methodology to assess the cytotoxicity and cell penetration of dendrigrafts of poly-L-lysine (DGLs) for potential use as nanoscale drug carriers for cancer treatment. The data suggests that DGLs exhibit cytotoxicity comparable to other dendrimers, are taken up by cancer cells quickly, and serum components can reduce their cytotoxicity.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Physical
Li Ye, Hongmei Liu, Xin Fei, Ding Ma, Xiaozhen He, Qianyun Tang, Xue Zhao, Hanbing Zou, Xiaojing Chen, Xianming Kong, Peifeng Liu
Summary: A surface modification strategy was used to enhance the endosomal escape ability of dendrimer DGL polymers, improving gene transfection efficiency. This strategy involved designing a library of PBA-modified DGL polymers to screen for efficient siRNA vectors, with one candidate showing nearly 90% gene silencing in cells. Furthermore, the PBA modification not only improved siRNA cellular uptake but also endowed DGL polymers with the ability to escape endosomes.
Review
Engineering, Environmental
Zhoujie Wang, Qiuyi Lu, Jingyi Wang, Jing Liu, Guangyi Liu, Wei Sun, Lei Xie, Qi Liu, Hongbo Zeng
Summary: Hydrophobic interactions are crucial in various mineral systems, affecting processes such as water treatment, particle separation, and self-cleaning or electrocatalysis in functional materials. The quantification and modulation of these interactions at the mineral/water interface provide insights into the underlying mechanisms of such particles’ interfacial processes. This review focuses on the nanomechanical understanding of hydrophobic interactions on mineral surfaces, discussing topics such as water structure, mineral surface wettability, agglomeration, bubble attachment, and adsorption of organics. The review also highlights the recent advances in using stimuli-responsive polymers to modulate hydrophobic interactions and identifies future research perspectives.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Energy & Fuels
Wenyuan Sun, Hongbo Zeng, Tian Tang
Summary: This study investigates the molecular interaction behaviors of a model asphaltene C5Pe between solid surfaces of varying polarity in different solvents using molecular dynamics simulations. The results reveal distinct adsorption behaviors driven by the interaction between C5Pe molecules and surfaces in solvents of different nature. The adsorption behaviors are influenced by the nature of the solvent and the polarity of the surfaces. Potential of mean force calculations demonstrate the interplay between enthalpy-driven adsorption and entropy-driven adsorption. The study provides a mechanistic understanding of asphaltene-surface interactions in solution media.
Article
Energy & Fuels
Xiaoyu Sun, Hongbo Zeng, Tian Tang
Summary: Water or brine co-exist with oil in the form of emulsions during petroleum production, which can be stabilized by surface-active components like asphaltenes. This study investigates the effect of salinity on the stability of water/oil interface with adsorbed asphaltenes and polymeric demulsifiers using molecular dynamics simulations. The results provide insights into the effect of salinity on the stabilization and destabilization of water/oil interface.
Article
Pharmacology & Pharmacy
Shammy Raj, Kosala D. Waduthanthri, Purushothaman Kuppan, Gregory S. Korbutt, Larry D. Unsworth, Andrew R. Pepper
Summary: Pancreatic islet transplantation is an effective strategy for restoring glucose regulation in type 1 diabetes patients. However, oxidative stress during the transplantation process often leads to islet cell death. The use of exogenous antioxidants has shown promise in protecting islet cell functionality and improving transplant outcomes.
ADVANCED THERAPEUTICS
(2023)
Article
Chemistry, Physical
Jingyi Wang, Jiawen Zhang, Sijia Li, Dengfeng Liu, Akhilesh Bhambhani, Hongbo Zeng
Summary: This article highlights the importance of characterizing the morphology and intermolecular interactions of RNA and lipid molecules using atomic force microscopy (AFM), as well as the application of AFM in this field. The first section introduces the use of AFM imaging to obtain high-resolution morphologies and nanostructures of RNA molecules in air and liquid, and discusses the application of AFM force spectroscopy to understand the nanomechanical properties and molecular interactions of RNA molecules. The second section focuses on the studies of lipid and RNA-lipid complexes using AFM, including sample preparation and factors influencing their morphology and structure. The future perspectives and challenges in the characterization of RNA and lipid using AFM techniques are also discussed.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Bo-Wen Zhang, Meng-Nan Zhu, Min-Rui Gao, Jian Chen, Xiuan Xi, Jing Shen, Ren-Fei Feng, Natalia Semagina, Nanqi Duan, Hongbo Zeng, Jing-Li Luo
Summary: The addition of B-sites breaks the trade-off between promoted exsolution and suppressed phase transition, expanding the application range of exsolution-facilitated perovskite materials. Using carbon dioxide electrolysis as a case study, this research shows that the catalytic activity and stability of perovskites with exsolved nanoparticles (P-eNs) can be enhanced by regulating the phase of host perovskites, emphasizing the important role of perovskite scaffold in catalytic reactions occurring on P-eNs. This concept may lead to the design of advanced exsolution-facilitated P-eNs materials and uncover a wide range of catalytic chemistry on P-eNs.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Engineering, Environmental
Tao Qin, Xukai Li, Anqi Yang, Meng Wu, Li Yu, Hongbo Zeng, Linbo Han
Summary: A temperature-tolerant, stretchable, adhesive, self-healing and conductive organohydrogel has been developed for flexible strain sensors. It can accurately monitor human joint movements, wrist pulses, micro-expressions, and vocal signals, and maintains excellent mechanical and electrical properties even in harsh environments or after long-term storage. Moreover, it can be integrated into wearable devices for intelligent speech-motion recognition, rehabilitation training, and human-computer interaction.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Chiranjeevi Kanike, Hongyan Wu, A. W. Zaibudeen, Yanan Li, Zixiang Wei, Larry D. Unsworth, Arnab Atta, Xuehua Zhang
Summary: The droplet-based biphasic reaction is used to fabricate ordered micro-ring arrays of silver nanostructures on a hydrophobic substrate for reproducible detection by surface-enhanced Raman spectroscopy (SERS). The technique allows for the production of a large SERS substrate, eliminating the need for sophisticated equipment. The repeatability of SERS measurements using silver nanostructures was demonstrated.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Qiuyi Lu, Jingyi Wang, Zhoujie Wang, Lei Xie, Qi Liu, Hongbo Zeng
Summary: Quantitative characterizations of HA-HA and HA-clay mineral systems in aqueous media at the nanoscale are important for understanding the aggregation and adsorption mechanism of humic acid in both terrestrial and aquatic environments. However, the molecular interactions of these systems in complex aqueous environments are still not well understood.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Energy & Fuels
An Li, Rui Li, Ci Yan, Han Wang, Qingxia Liu, Jacob H. Masliyah, Hongbo Zeng, Zhenghe Xu
Summary: This study aims to understand the effects of different types and wettability of clays on bitumen extraction from mined oil sands. The results showed that hydrophilic clays had a detrimental effect on the extraction process, with montmorillonite being the worst. The crucial role of clays in slime-coating on bitumen was studied, and clay concentration was found to determine the hetero-coagulation process between bitumen and clay.
Review
Chemistry, Physical
Meng Wu, Jifang Liu, Xiaogang Wang, Hongbo Zeng
Summary: Infections can have serious health consequences, including death. Surfaces, such as biomedical devices, implants, textiles, tables, and doorknobs, serve as carriers for pathogens to move, attach, and multiply. Implementing antimicrobial surfaces is a reliable and long-lasting approach to combat surface transmission of germs, reduce microbial colonization, and decrease infections. This review presents recent advancements in antimicrobial surfaces, categorized into four groups based on their mechanisms of action: antifouling, bactericidal, antifouling and bactericidal, and dynamic or stimuli-responsive surfaces. The review discusses the fabrication processes and properties of each category, along with their structure-performance relationships. Special attention is given to various anchoring strategies involving tunable molecular interactions. Relevant biomedical applications are also introduced.
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Cynthia E. Ibarra Torres, Thelma E. Serrano Quezada, Oxana V. Kharissova, Hongbo Zeng, Boris I. Kharisov, Edith Luevano Hipolito, Leticia M. Torres-Martinez, Lucy T. Gonzalez
Summary: In order to address environmental issues caused by oil spills and other organic liquid leaks, we have developed graphene/hollow carbon fiber composite aerogels (G-CF) with low density, high hydrophobicity, buoyancy, and adsorption capacity of up to 42.7 g g-1.
MENDELEEV COMMUNICATIONS
(2023)
Article
Engineering, Chemical
Xuyi Wei, Xiaohui Mao, Wenqing Qin, Hongbo Zeng, Junwei Han
Summary: In this study, a natural kaolinite loaded onto alginate hydrogel was used to prepare ALG@KLN composites, which achieved efficient recovery of rare earth elements (REEs) using an eco-friendly method. ALG@KLN exhibited high adsorption capacity and reusability, and the adsorption mechanism was mainly through chemical chelation and electrostatic interaction. This research is of great significance for the development of economical and eco-friendly REE adsorbents.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Engineering, Chemical
Qing Sun, Jingsi Chen, Ziqian Zhao, Diling Yang, Yaoyu Xiao, Hao Zhang, Xin Ma, Hong Zhong, Hongbo Zeng
Summary: In this study, a pH-responsive surfactant was developed, which selectively interacted with different target substances through two pH-switchable functional groups, enabling stepwise and efficient separation of a three-component mineral system.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Xiao He, Ruijie Yang, Chaochen Xu, Ziqian Zhao, Y. Frank Cheng, Philip Egberts, Hongbo Zeng, Qingye Lu
Summary: Compared to in situ preparation, ex situ strategies greatly increase the convenience of preparing hydrogel coatings. However, the difficulty in preparing sub-micron-thick coatings limits their use in nanotechnology.
