Article
Chemistry, Multidisciplinary
Zhongwei Man, Zheng Lv, Zhenzhen Xu, Jiannian Yao, Hongbing Fu
Summary: This study demonstrates the construction of supramolecular nanoassemblies (SNAs) through host-guest interactions between isopercolic acid derivatives (IADs) and cyclodextrin (CD), resulting in improved fluorescence quantum yield and suppression of nonradiative relaxation pathways. The SNAs showed high stimulated emission efficiency and excellent STED imaging performance, paving a new pathway for the development of novel high-performance STED probes.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Evelyn Y. Xue, Caixia Yang, Wing-Ping Fong, Dennis K. P. Ng
Summary: In this study, a supramolecular photosensitizing nanosystem that can be specifically activated in cancer cells and tumors overexpressing EGFR was reported. The nanosystem showed a small particle size and could restore its photoactivity, leading to effective eradication of tumors in experiments.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Jie Lu, Yingying Deng, Peng Liu, Qingqing Han, Long Yi Jin
Summary: In this study, the self-assembly of amphiphilic di-macrocyclic host molecules based on beta-cyclodextrin and pillar[5]arene units linked by azophenyl or biphenyl groups was reported. H-1 formed unique nanorings and exhibited photoresponsive colour change, making it suitable for application in carbon paper materials. H-2 formed spherical micelles. These differences were attributed to changes in intermolecular and hydrophilic-hydrophobic interactions caused by different linker units.
Article
Chemistry, Medicinal
Tetsuya Kogo, Kosei Utatsu, Toru Taharabaru, Risako Onodera, Keiichi Motoyama, Taishi Higashi
Summary: The study evaluated the application of a supramolecular polymer, NH2-PRX, as a pharmaceutical excipient for protein drugs. NH2-PRX showed significant reduction in protein aggregation and adsorption onto containers, while maintaining the bioactivity of insulin.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Chemistry, Physical
Roberto Zagami, Anna Barattucci, Luigi Monsu Scolaro, Maurizio Viale, Giuseppina Raffaini, Paola Maria Bonaccorsi, Antonino Mazzaglia
Summary: This article introduces the potential application of non-ionic cyclodextrin-based nanoassemblies as nanocomplex adjuvants in anticancer therapy. The nanoassemblies were prepared by solvent evaporation method and characterized by spectroscopic techniques. Theoretical studies were performed to understand the formation and stability of the nanoassemblies. Experimental results showed that the nanoassemblies exhibited similar anticancer activity to free curcumin in different cancer cell lines.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Pharmacology & Pharmacy
Yaxin Zheng, Xue Ying, Yue Su, Xuan Jin, Qiulin Xu, Yang Li
Summary: The study found that nanocarriers with high kinetic stability showed lower in vitro cytotoxicity but were more effective in inhibiting tumor growth, although they also resulted in increased toxicity due to high prodrug accumulation in tissues. This highlights the pivotal role of kinetic stability in determining the antitumor efficacy of prodrug nanoassemblies and provides new insights into the delivery mechanism for small-molecule prodrug self-delivering nanosystems.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Physical
Bobo Zhou, Wanli Kang, Hongbin Yang, Zhe Li, Hongwen Zhang, Min Zhang, Anqing Xie, Zhuangwei Sun, Bauyrzhan Sarsenbekuly
Summary: The study introduces CADC inclusion gel, which improves the shear stability of the gel by reorganizing amphiphilic polymer with cyclodextrin structure. The inclusion gel solves the issue of poor shear resistance ability of amphiphilic polymer gel and has the potential to replace it for water shutoff applications in oilfield.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Min Zhang, Wanli Kang, Hongbin Yang, Zhe Li, Hongwen Zhang, Fang Wang, Menlan Li, Xin Kang, Haizhuang Jiang, Anqing Xie
Summary: The study investigates the effect of host-guest inclusion on emulsion stability, constructing two inclusion complexes and analyzing the stability mechanism. The results show that the CDP-APC(16) inclusion complex emulsion exhibits better stability and potential application in tertiary oil recovery.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Pharmacology & Pharmacy
Peng Yu, Zhao Xu, Xueyuan Zhai, Yanpeng Liu, Hui Sun, Xinyuan Xu, Jing Xie, Jianshu Li
Summary: The nanoassemblies of salmon calcitonin-aspartame (sCT-APM) delay fibrillation time, achieve sustained release of sCT, exhibit good biocompatibility and higher osteoinductive capacity, leading to an improvement in bone growth. In vivo studies show enhanced relative bioavailability and increased therapeutic efficacy of sCT-APM compared to free sCT through subcutaneous injection, providing a convenient alternative strategy for osteoporosis therapy via supramolecular assemblies.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Physical
Giulia Neri, Annalaura Cordaro, Angela Scala, Massimiliano Cordaro, Antonino Mazzaglia, Anna Piperno
Summary: The incorporation of gold nanoparticles on graphene enhances optical absorption and improves the performance of optoelectronic devices, while using polymeric matrices as reducing and capping agents is a successful strategy to achieve this objective. The combination of various functionalities, such as hydroxyl groups and amino groups on cyclodextrin, allows for the eco-friendly synthesis of Au NPs in a supramolecular assembly.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Food Science & Technology
Jingyan Pei, Xinchang Gao, Daodong Pan, Ying Hua, Jun He, Zhu Liu, Yali Dang
Summary: Bioactive peptides are widely used in functional foods but face challenges in terms of quality stability and efficacy in vivo. This review discusses the stability issues in the production and administration of bioactive peptides and provides strategies for improvement, such as the use of fingerprinting as a quality control measure and chemical modification and encapsulation for improved stability.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
Review
Chemistry, Applied
Zhihuan Huang, Jiazhi Chen, Rong Li, Suqing Shi, Yong-Kuan Gong
Summary: Surface fouling is a common problem that leads to economic loss and health risks in all materials and devices. Inspired by the antifouling nature of cell membrane, zwitterionic coating antifouling strategy has been developed as a strong technique. The use of self-adhesive polydopamine (PDA) enables the construction of cell membrane mimetic antifouling coatings on all materials and devices. This review summarizes the design concepts, construction techniques, and recent progress of antifouling zwitterionic polymer coating applications, with emphasis on coating stability and crosslinking enhancement for practical use.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Materials Science, Multidisciplinary
Yue Liu, Hang Yang, Yue Wu, Hongyu Fan, Xiaoxiao Li, Kewei Hu, Yongfang Li, Chaohua Cui
Summary: Curcumin is used as a modifier for zinc oxide (ZnO) electron transport layers in inverted organic solar cells (i-OSCs) to simultaneously improve efficiency and photostability. E100 modifies ZnO by aligning energy levels and optimizing surface morphology, improving charge transport and recombination properties. Using ZnO/E100 as the electron transport layer results in enhanced efficiency and photostability compared to using ZnO alone.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Review
Chemistry, Applied
Zuobing Xiao, Yaqi Zhang, Yunwei Niu, Qinfei Ke, Xingran Kou
Summary: Cyclodextrins are natural cyclic compounds that are edible and biocompatible, capable of encapsulating essential oils, flavors, and other substances to improve their solubility and stability. The development of CD/volatile compound nanosystems is crucial in the food, cosmetic, and pharmaceutical industries.
CARBOHYDRATE POLYMERS
(2021)
Review
Chemistry, Physical
Jiaqiang Huang, Zongxue Yu, Junlei Tang, Pingquan Wang, Qiuyue Tan, Juan Wang, Xianzhang Lei
Summary: This paper reviews the performance, synthesis and modification methods, and alkaline stability protection of anion-exchange polyelectrolytes (AEPs) in alkaline fuel cells, and summarizes the current research and development status. The evaluation and comparison of different types of AEPs and AEMs deepen the understanding of AEPs in AEMFC.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
