Article
Multidisciplinary Sciences
Thomas Swift, Emily Caseley, Abbigail Pinnock, Joanna Shepherd, Nagaveni Shivshetty, Prashant Garg, C. W. Ian Douglas, Sheila MacNeil, Stephen Rimmer
Summary: Branched poly(N-isopropylacrylamide) functionalized with Amphotericin B displayed antifungal properties, inhibiting certain strains effectively. The polymer exhibited lower toxicity to corneal and renal cells, as well as explanted corneal tissue, compared to the free drug.
ROYAL SOCIETY OPEN SCIENCE
(2021)
Article
Polymer Science
M. Bhagya Dharmasiri, T. Kuruwita Mudiyanselage
Summary: Highly porous and fast-responding PNIPAM hydrogels were prepared by emulsion-templated polymerization using virgin coconut oil, showing approximately seven times faster response rate than conventional PNIPAM hydrogels.
Article
Polymer Science
Katharina Nieswandt, Prokopios Georgopanos, Martin Held, Evgeni Sperling, Volker Abetz
Summary: Thermoresponsive copolymers were synthesized and their thermoresponsive properties were characterized. The copolymers showed a lower critical solution temperature in water, which depended on the molar fraction of one of the monomers. Block copolymers were also prepared using a surfactant-free emulsion polymerization method, and their thermoresponsive behavior in a confined state was investigated. The nanospheres showed a linear change in hydrodynamic radius with temperature, and the addition of certain salt anions affected the collapse of the nanospheres' corona.
Article
Chemistry, Multidisciplinary
Jie Liu, Yuling Sun, Xiaoteng Zhou, Xiaomei Li, Michael Kappl, Werner Steffen, Hans-Juergen Butt
Summary: This research introduces a one-step grafting method for poly(dimethylsiloxane) (PDMS) brushes on surfaces, meeting the requirements of fast, easy, universal, stable, robust, and environmentally friendly coatings. The coatings exhibit excellent sliding properties and high temperature resistance, making them an ideal solution for long-term degradation issues of coatings for heat-transfer surfaces.
ADVANCED MATERIALS
(2021)
Article
Polymer Science
Shahzad Iqbal, Farid Ahmed, Ziyan Wang, Weiqing Xu, Yating Zeng, Hai Xiong
Summary: Copolymers of N-isopropylacrylamide (NIPAM) and tetraphenylethene (TPE) acrylamide monomers with aggregation-induced emission (AIE) activity, namely P1, P2, and P3, were synthesized with relatively lower molecular weights (6000). These copolymers, similar to poly-N-isopropylacrylamide (p-NIPAM), showed fluorescence intensity change in response to temperature due to conformational transition (swelling/shrinking) below or above their lower critical solution temperature (LCST) in aqueous solution. The LCST of p-NIPAM (32 degrees C) decreased when TPE was incorporated into the copolymer chains, depending on the TPE concentration. The fluorescence response of P1 increased by five-fold with increasing tannic acid (TA) concentration, forming P1-TA complexes. Surprisingly, the fluorescence response of the P1-TA complex changed under the influence of temperature and pH value. Dynamic light scattering (DLS) measurements of P1-TA confirmed the fluorescence response based on particle size at different concentrations and pH values. These stimuli-responsive AIE-active copolymers show potential applications in monitoring drug loading and release processes in drug delivery systems using fluorescence.
Article
Biochemistry & Molecular Biology
Zhengxian Wang, Jiankang Lu, Chengyi Wu, Youmeng Dan, Guoxiang Li, Deyong Wu, Sheng Hu
Summary: Poly(N-isopropyl acrylamide) and its derived copolymer have important applications as a temperature-responsive material in the fields of anticancer drug carrier and slow-release fertilizer. In this study, a smart poly(N-isopropyl acrylamide-co-acrylamide)-coated Alg-BMOF (PABMOF) was synthesized in an ionic liquids microemulsion as a nano-reactor. The PABMOF exhibited excellent adsorption properties towards H2PO4- and showed temperature-responsive behavior. Moreover, the addition of PABMOF improved the water-holding and water-retention capacity of soil and promoted the growth of Chinese cabbage.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Phanicha Wiwatsamphan, Suwabun Chirachanchai
Summary: This study proposes a simple approach to achieve persistently reversible multi-responsive hydrogels by crosslinking two responsive interpenetrating networks (CN-IPNs). The CN-IPNs hydrogel maintains reversible pH-/thermo-responsiveness even after multiple treatment cycles, demonstrating its potential for long-lasting performance in advanced bio-related applications.
POLYMER DEGRADATION AND STABILITY
(2022)
Article
Polymer Science
Zhongming Liu, Sufeng Zhang, Chao Gao, Xia Meng, Shoujuan Wang, Fangong Kong
Summary: Temperature/pH-responsive CMC/Ca2+/PNIPAM aerogels were developed as a novel drug delivery system. The aerogels have a highly open network structure and multiple active sites, making them suitable for drug loading and sustained release. Characterization of the aerogels confirmed their non-toxicity and good temperature and pH response performance.
Article
Chemistry, Multidisciplinary
Shuai Li, Youmin Hou, Michael Kappl, Werner Steffen, Jie Liu, Hans-Juergen Butt
Summary: This study shows that exposing the surface of PDMS brushes to organic solvent vapors can effectively reduce water droplet adhesion, allowing for fast removal of water droplets and de-icing.
ADVANCED MATERIALS
(2022)
Article
Polymer Science
Fatma Kursun Baysak, Nuran Isiklan
Summary: The poly(N-hydroxymethyl acrylamide) grafted poly(vinyl alcohol) membranes show efficient separation of isopropyl alcohol (IPA) via pervaporation. The increase in grafting percentage leads to higher flux and separation factor, and the swelling behavior of the membranes is consistent with pervaporation results.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Chemistry, Physical
Cristiane Henschel, Dirk Schanzenbach, Andre Laschewsky, Chia-Hsin Ko, Christine M. Papadakis, Peter Mueller-Buschbaum
Summary: Sets of nonionic polymers pNVIBAm and pNIPMAm with molar mass from 20,000 to 150,000 kg mol-1 are synthesized by radical polymerization, and their thermoresponsive and solvent-responsive behaviors in aqueous solution are studied. Both polymers exhibit a rare type II lower critical solution temperature (LCST), similar to well-studied pNIPAm. Additionally, both polymers display co-nonsolvency behavior in mixtures of water with various co-solvents, but the co-nonsolvency becomes less pronounced in the order pNIPAm > pNVIBAm > pNIPMAm. Notably, pNIPMAm does not exhibit co-nonsolvency in mixtures of water and N,N-dimethylformamide.
COLLOID AND POLYMER SCIENCE
(2023)
Article
Spectroscopy
Cheng Cheng, Juan Qiao, Hongyi Zhang, Zhenwen Zhao, Li Qi
Summary: Recently, the loading of polymer-ligand onto the surface of gold nanoparticles as nanozymes has attracted attention. A study reported a method to modulate the peroxidase-mimic catalytic capability of PNIPAM@AuNPs by changing temperature. The presence of glutathione inhibits the generation of oxidized TMB, and the method could be used for the analysis of serum glutathione.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Physical
Zhibin Zhang, Xi Wang, Hongyan Li, Gengchen Liu, Kaiying Zhao, Yajun Wang, Zheng Li, Jianying Huang, Zhiwei Xu, Yuekun Lai, Xiaoming Qian, Songnan Zhang
Summary: In this study, an innovative atmospheric water harvester combining hydrogel and 3D raised-fabric was developed, which exhibited excellent photothermal conversion performance and adsorption capacity, making it effective for water collection and storage.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Review
Biophysics
Saeid Shabestari Khiabani, Marziyeh Aghazadeh, Jamshid Rakhtshah, Soodabeh Davaran
Summary: This review discusses the potential of injectable N-isopropyl acrylamide-based hydrogels in bone fracture repair, for delivering scaffolds, cells, and growth factors.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Applied
Behrouz Foroughi-Nia, Ayuob Aghanejad, Jamileh Kadkhoda, Jaleh Barar, Hamed Nosrati, Soudabeh Davaran
Summary: This study developed a magnetic pH-dependent and nucleolin receptor-targeted nano-drug delivery system to deliver ERL to prostate cancer cells. The system had high encapsulation efficiency, properly sized nanoparticles, and induced cancer cell death through pH-sensitive release of ERL.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)