New insights into pre-mRNA processing factor 19: A multi-faceted protein in humans

ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis

(2016) Hanna Dellago et al.   Aging-US

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

(2012) Frédérick A Mallette et al.   EMBO JOURNAL

Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity

(2012) Zhaoyang Niu et al.   FEBS LETTERS

Mirtrons: microRNA biogenesis via splicing

(2011) Jakub O. Westholm et al.   BIOCHIMIE

SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing

(2011) Y. Chen et al.   GENES & DEVELOPMENT

The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes

(2011) S. Chanarat et al.   GENES & DEVELOPMENT

The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex

(2011) C. J. David et al.   GENES & DEVELOPMENT

Systematic Two-Hybrid and Comparative Proteomic Analyses Reveal Novel Yeast Pre-mRNA Splicing Factors Connected to Prp19

(2011) Liping Ren et al.   PLoS One

Feed-Forward Microprocessing and Splicing Activities at a MicroRNA–Containing Intron

(2011) Maja M. Janas et al.   PLoS Genetics

Regulation of Metnase’s TIR binding activity by its binding partner, Pso4

(2010) Brian D. Beck et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Human PRP19 interacts with prolyl-hydroxylase PHD3 and inhibits cell death in hypoxia

(2010) Masuhiro Sato et al.   EXPERIMENTAL CELL RESEARCH

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

(2010) C. J. David et al.   GENES & DEVELOPMENT

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome

(2010) E. J. Song et al.   GENES & DEVELOPMENT

Molecular Architecture of the Human Prp19/CDC5L Complex

(2010) M. Grote et al.   MOLECULAR AND CELLULAR BIOLOGY

A Splicing-Independent Function of SF2/ASF in MicroRNA Processing

(2010) Han Wu et al.   MOLECULAR CELL

The Prp19 WD40 Domain Contains a Conserved Protein Interaction Region Essential for Its Function

(2010) Craig W. Vander Kooi et al.   STRUCTURE

DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation

(2009) Manuel J. Muñoz et al.   CELL

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner

(2009) Bing Liao et al.   CELL RESEARCH

Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint

(2009) Nianxiang Zhang et al.   EMBO REPORTS

Blom7α Is a Novel Heterogeneous Nuclear Ribonucleoprotein K Homology Domain Protein Involved in Pre-mRNA Splicing That Interacts with SNEVPrp19-Pso4

(2009) Johannes Grillari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Association of the Microprocessor Complex with the Spliceosome

(2009) N. Kataoka et al.   MOLECULAR AND CELLULAR BIOLOGY

Nonproteolytic Functions of Ubiquitin in Cell Signaling

(2009) Zhijian J. Chen et al.   MOLECULAR CELL

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

(2009) Yaron Galanty et al.   NATURE

Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor

(2009) S Confalonieri et al.   ONCOGENE

SMN Deficiency Causes Tissue-Specific Perturbations in the Repertoire of snRNAs and Widespread Defects in Splicing

(2008) Zhenxi Zhang et al.   CELL

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Human Pso4 Is a Metnase (SETMAR)-binding Partner That Regulates Metnase Function in DNA Repair

(2008) Brian D. Beck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

(2008) Jan M. Pawlicki et al.   JOURNAL OF CELL BIOLOGY

CHIP-Mediated Degradation and DNA Damage-Dependent Stabilization Regulate Base Excision Repair Proteins

(2008) Jason L. Parsons et al.   MOLECULAR CELL

A role for ubiquitin in the spliceosome assembly pathway

(2008) Priya Bellare et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY