Review
Cell Biology
Chien-Chu Huang, Ya-Wen Hsueh, Chia-Wei Chang, Hsi-Chen Hsu, Tung-Chuan Yang, Wu-Chou Lin, Hsun-Ming Chang
Summary: Early pregnancy is a complex process involving cellular elements of the fetal-maternal interface, and abnormalities in trophoblast-decidual interactions can lead to miscarriage and later pregnancy disorders. Although research has been performed in various species, there is significant species variation in trophoblast differentiation and gene regulation. Recent advancements in technology have allowed a comprehensive understanding of human implantation and placentation, and the clinical utility of fetal-maternal cellular trafficking has been explored for prenatal diagnosis and prediction of pregnancy complications. Therapeutic strategies targeting placenta-enriched molecules have also been proposed for placental dysfunction and diseases.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Reproductive Biology
Zengyou Ma, Haoyi Zheng, Xiaoping Li, Beibei Yu, Hui Peng
Summary: This study investigates the expression, localization, and function of CSNK1A1 in early embryonic development in mice. CSNK1A1 is expressed in multiple mouse tissues, including the ovary, and its highest expression is observed in two-cell-stage embryos. Inhibition or knockdown of CSNK1A1 leads to a decrease in blastocyst formation and embryonic developmental arrest. These findings provide novel insights into the role of CSNK1A1 in early embryonic development.
Article
Agriculture, Dairy & Animal Science
Juan P. Cabeza, Juan Camera, Olinda Briski, Minerva Yauri Felipe, Daniel F. Salamone, Andres Gambini
Summary: This study investigates the use of a novel zinc chelator for activating bovine and porcine oocytes. The results show that the zinc chelator can successfully induce blastocyst development in both species, although developmental rates and embryo quality are compromised in bovine compared to calcium-induced embryos. On the contrary, the new concentration and incubation time of the zinc chelator improve developmental rates in porcine without affecting embryo quality. These findings contribute to understanding the role of zinc in oocyte activation and preimplantation embryo development across different mammalian species.
Article
Biochemistry & Molecular Biology
Kirill Salewskij, Theresa Gross-Thebing, Elizabeth Ing-Simmons, Binyamin Duethorn, Bettina Rieger, Rui Fan, Rui Chen, Niraimathi Govindasamy, Heike Brinkmann, Ludmila Kremer, Nannette Kuempel-Rink, Karina Mildner, Dagmar Zeuschner, Martin Stehling, Marion Dejosez, Thomas P. Zwaka, Hans R. Schoeler, Karin B. Busch, Juan M. Vaquerizas, Ivan Bedzhov
Summary: During implantation, Ronin is crucial for enabling active energy production, promoting naive pluripotency, and fine-tuning the expression of genes encoding ribosomal proteins. Ronin is essential for governing the metabolic capacity in supporting high-energy demands for cell proliferation and morphogenesis in the pluripotent lineage.
Article
Biochemistry & Molecular Biology
Krzysztof Lukaszuk, Amira Podolak
Summary: This retrospective case control study found that mtDNA copy number is higher in aneuploid embryos compared to euploid embryos, but no significant differences were observed in relation to embryo morphology, genetic sex, maternal age, or implantation ability. Therefore, mtDNA has the potential to serve as an additional independent biomarker for embryo selection.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Agriculture, Dairy & Animal Science
H. Lindeberg, E. Nikitkina, Sz Nagy, A. Musidray, G. Shiryaev, J. Kumpula, O. Holand
Summary: The use of assisted reproductive technology in reindeer husbandry has gained increasing interest in recent decades. This review summarizes literature on semen collection, cryopreservation, artificial insemination, synchronisation of estrous cycles, embryo recovery, embryo transfer, in vitro embryo production, and pregnancy diagnosis in reindeer.
ANIMAL REPRODUCTION SCIENCE
(2021)
Review
Agriculture, Dairy & Animal Science
Carolina Acevedo, Jennifer P. Barfield
Summary: To conserve the important species of bison in Europe and North America, conservation efforts have focused on establishing sustainable herds through the use of assisted reproductive technologies (ARTs). These technologies facilitate the transfer of genetics and offer protection against future losses of genetic diversity. Research on ART for bison has made progress, but there are still opportunities for improvement and expanding their impact on bison conservation.
Review
Agriculture, Dairy & Animal Science
Carolina Acevedo, Jennifer P. Barfield
Summary: Bison are important species ecologically and culturally, and conservation efforts are focused on building sustainable herds using assisted reproductive technologies. This review discusses the current state of ART in American bison and European bison, highlighting the potential for genetic conservation and the need for further improvement and expansion of these technologies.
Article
Obstetrics & Gynecology
Manish Banker, Silke Dyer, Georgina M. Chambers, Osamu Ishihara, Markus Kupka, Jacques de Mouzon, Fernando Zegers-Hochschild, G. David Adamson
Summary: The report provides data on the utilization, effectiveness, and safety of assisted reproductive technology (ART) globally in 2013, showing an increase in ART cycles and changes in trends such as a rise in the proportion of older women undergoing non-donor ART. Further efforts are needed to improve the quality and consistency of reporting ART data by registries.
FERTILITY AND STERILITY
(2021)
Article
Cardiac & Cardiovascular Systems
Maria C. Magnus, Abigail Fraser, Siri E. Haberg, Kristiina Rono, Liv Bente Romundstad, Christina Bergh, Anne Laerke Spangmose, Anja Pinborg, Mika Gissler, Ulla-Britt Wennerholm, Bjorn Olav Asvold, Deborah A. Lawlor, Signe Opdahl
Summary: This study examines the associations between different combinations of aerobic and muscle strengthening activity with mortality rates. The findings suggest that balanced levels of aerobic activity and muscle strengthening may reduce the risk of mortality.
Article
Cardiac & Cardiovascular Systems
Maria C. Magnus, Abigail Fraser, Siri E. Haberg, Kristiina Rono, Liv Bente Romundstad, Christina Bergh, Anne Laerke Spangmose, Anja Pinborg, Mika Gissler, Ulla-Britt Wennerholm, Bjorn Olav Asvold, Deborah A. Lawlor, Signe Opdahl
Summary: A study using nationwide data from Denmark, Finland, Norway, and Sweden found that women who gave birth after assisted reproductive technologies (ART) did not have an increased risk of cardiovascular disease (CVD) compared to those who conceived without ART during a median follow-up of 11 years. Longer-term studies are needed to further investigate the association between ART and higher risk of CVD.
Article
Reproductive Biology
Ayumi Hasegawa, Keiji Mochida, Shogo Matoba, Kimiko Inoue, Daiki Hama, Masayo Kadota, Noriko Hiraiwa, Atsushi Yoshiki, Atsuo Ogura
Summary: This study developed assisted reproductive technologies for wild-derived Mus spretus mice, enabling efficient production of embryos and successful interspecies embryo transfer into laboratory mice, demonstrating the potential for safe preservation and utilization of strains in research settings.
BIOLOGY OF REPRODUCTION
(2021)
Article
Chemistry, Multidisciplinary
Irene Sanchez-Ajofrin, Carlos M. Andreu, Josue M. Galindo, Irene San-Millan, Sonia Merino, Ana Josefa Soler, M. Antonia Herrero, Ester Vazquez
Summary: Oocyte in vitro maturation (IVM) is a potential alternative in assisted reproductive technologies, but current protocols yield inferior quality oocytes. A bilayer hydrogel system that accurately mimics the mechanical properties of oocyte maturation microenvironment significantly improves oocyte quality and developmental capacity, representing a significant advancement in assisted reproductive technologies.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Medicine, Research & Experimental
Ella S. Green, Lachlan M. Moldenhauer, Holly M. Groome, David J. Sharkey, Peck Y. Chin, Alison S. Care, Rebecca L. Robker, Shaun R. McColl, Sarah A. Robertson
Summary: Using a mouse model, this study found that regulatory T cells (Treg cells) play a crucial role in mediating the effects of progesterone on uterine receptivity by repairing blood vessel remodeling and placental structure, and restoring T cell imbalance in the mother, thereby alleviating fetal loss and growth restriction caused by reduced progesterone signaling.
Article
Obstetrics & Gynecology
Juan J. Fraire-Zamora, Meritxell Martinez, Marc Torra-Massana, Irene Miguel-Escalada, Rita Vassena
Summary: This study found no significant differences in morphokinetic parameters between male and female preimplantation embryos.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)