Review
Food Science & Technology
Mousa Khalafi, Karim Azali Alamdari, Michael E. Symonds, Hadi Rohani, Mohammad Hossein Sakhaei
Summary: This study conducted a systematic meta-analysis to compare the effect of exercise training (Ex) combined with dietary interventions (DI) versus DI alone on insulin resistance (IR) and glucose homeostasis. The results showed that Ex + DI had a greater decrease in fasting glucose and IR compared to DI alone, but there was no significant difference in fasting insulin and body weight between the two interventions.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Biochemistry & Molecular Biology
Zhen Zeng, Christoph Centner, Albert Gollhofer, Daniel Koenig
Summary: Whole dietary strategies rich in antioxidants have gained attention for their potential to alleviate exercise-induced oxidative stress, with most studies showing favorable effects. However, research on the effects of such strategies on oxidative stress is still limited, and further systematically designed studies are needed to strengthen the evidence.
Review
Biochemistry & Molecular Biology
Megumi Kishimoto-Urata, Shinji Urata, Chisato Fujimoto, Tatsuya Yamasoba
Summary: Oxygen metabolism in the mitochondria is crucial for biological activity, but it also produces reactive oxygen species (ROS) in cells. Imbalance between ROS production and degradation can lead to cell damage. Sensory organs, especially those for hearing, are constantly exposed and can cause hearing loss depending on the environment. Hair cells, spiral ganglion cells, and the stria vascularis in the auditory pathway, where mitochondria are abundant, are the main targets of ROS. Excessive ROS in auditory sensory organs are known to cause sensorineural hearing loss, and mitochondria-targeted antioxidants are potential treatments. This review focuses on the relationship between acquired hearing loss and antioxidant use, providing an overview of novel antioxidants, including medications, supplements, and natural foods, based on clinical, animal, and cell culture studies.
Article
Endocrinology & Metabolism
Alic Bellicha, Marleen A. van Baak, Francesca Battista, Kristine Beaulieu, John E. Blundell, Luca Busetto, Eliana V. Carraca, Dror Dicker, Jorge Encantado, Andrea Ermolao, Nathalie Farpour-Lambert, Adriyan Pramono, Euan Woodward, Jean-Michel Oppert
Summary: This overview summarizes the positive effects of exercise training on weight loss and body composition changes in overweight or obese adults, showing significant reductions in fat and visceral fat. Resistance training can help reduce muscle mass loss during weight loss. However, exercise did not show significant effects on weight maintenance.
Article
Public, Environmental & Occupational Health
Susan M. Devaraj, Jenna M. Napoleone, Rachel G. Miller, Bonny Rockette-Wagner, Vincent C. Arena, Chantele Mitchell-Miland, Mohammed Bu Saad, Andrea M. Kriska
Summary: The study investigated disparities in the success of DPP-translation program primary goal achievement across sociodemographic subgroups. Results showed that most sociodemographic subgroups demonstrated significant weight loss, with non-Hispanic white achieving greater weight loss compared to non-Hispanic black participants. Employment status was significantly related to weight loss, with retired participants being the most successful. Men, participants with graduate degrees, and those with higher income were most likely to meet the activity goal. Differences in physical activity goal achievement across gender, education, and income groups were significant at baseline, attenuated after 6 months, then re-emerged at 12 months.
Article
Medicine, General & Internal
Franziska Koppe-Schmeisser, Melanie Schwaderlapp, Julian Schmeisser, Joern F. Dopheide, Thomas Muenzel, Andreas Daiber, Christine Espinola-Klein
Summary: In patients with intermittent claudication, a combination of endovascular therapy and exercise training reduces inflammation by decreasing oxidative stress, leading to improved ankle-brachial index (ABI), absolute and initial claudication distances (ACD, ICD). This combination approach also results in lower leukocyte activation state and reduced ROS production, indicating its effectiveness in managing intermittent claudication.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Pauline Po Yee Lui, Xing Zhang, Shiyi Yao, Haonan Sun, Caihao Huang
Summary: Both acute and chronic tendon injuries are difficult to treat currently. This review explores the potential relationship between oxidative stress and tendon disorders. Inhibiting oxidative stress has been shown to promote tenogenic differentiation and enhance tendon repair. Anti-oxidative therapies have been researched to reduce tendon fibrosis and adhesion, and promote healing in tendinopathy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Food Science & Technology
Mousa Khalafi, Michael E. Symonds, Amir Akbari
Summary: The study compared the effects of exercise training (EX), caloric restriction (CR), and a combination of both on inflammatory markers in overweight and obese individuals. The results indicate that a combination of exercise and caloric restriction may be more effective at reducing inflammatory markers compared to caloric restriction alone in this population.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Anna Freeman, Doriana Cellura, Magdalena Minnion, Bernadette O. Fernandez, Cosma Mirella Spalluto, Denny Levett, Andrew Bates, Timothy Wallis, Alastair Watson, Sandy Jack, Karl J. Staples, Michael P. W. Grocott, Martin Feelisch, Tom M. A. Wilkinson
Summary: This study showed that personalized exercise intervention in asthma patients can improve symptoms, lung inflammation, physical fitness, and overall quality of life. Exercise also led to increased antioxidant capacity, improved lung function, reduced airway hyperreactivity, and decreased eosinophilic inflammation in the participants.
Review
Biochemistry & Molecular Biology
Zhanyi Zhou, Chaoyi Chen, Ee-Chon Teo, Yan Zhang, Jialu Huang, Yining Xu, Yaodong Gu
Summary: Exercise programs can improve an individual's antioxidative capacity, but inappropriate programs can induce oxidative stress. The severity of oxidative stress depends on the intensity and volume of exercise, as well as the individual's health condition. Recommendations include continuous aerobic exercise under moderate intensity or high-intensity interval training to enhance the body's redox balance, especially for unhealthy individuals.
Review
Nutrition & Dietetics
Kosar Valaei, Shima Taherkhani, Hamid Arazi, Katsuhiko Suzuki
Summary: Reactive oxygen species (ROS) play a crucial role in the pathophysiology of cardiac diseases, leading to cellular and molecular disorders that can result in heart dysfunction. New experimental treatments such as creatine supplementation, omega-3 fatty acids, and others have shown beneficial effects in improving oxidative stress.
Article
Endocrinology & Metabolism
Kelly E. Mercer, Adrianna Maurer, Lindsay M. Pack, Kikumi Ono-Moore, Beverly J. Spray, Caitlin Campbell, Carol J. Chandler, Dustin Burnett, Elaine Souza, Gretchen Casazza, Nancy Keim, John Newman, Gary Hunter, Jose Fernadez, W. Timothy Garvey, Mary-Ellen Harper, Charles Hoppel, Sean H. Adams, John Thyfault
Summary: Exercise and diet-induced weight loss in obese, sedentary, insulin-resistant women significantly impact bile acid metabolism, leading to a decrease in fasting serum BA concentrations and an increase in C4 concentrations. Furthermore, post-intervention, the responsiveness of bile acid synthesis to postprandial inhibition is improved after exercise and weight loss.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Nutrition & Dietetics
Sara Naimimohasses, Philip O'Gorman, Ciara Wright, Deirdre Ni Fhloinn, Dean Holden, Niall Conlon, Ann Monaghan, Megan Kennedy, John Gormley, Peter Beddy, Stephen Patrick Finn, Joanne Lysaght, Jacintha O'Sullivan, Margaret R. Dunne, Suzanne Norris, J. Bernadette Moore
Summary: This study found that dietary and exercise interventions have independent benefits for NAFLD patients, and intrahepatic MAIT cells may play a role in the observed histological improvements.
Article
Cardiac & Cardiovascular Systems
Daniel H. Craighead, Thomas C. Heinbockel, Kaitlin A. Freeberg, Matthew J. Rossman, Rachel A. Jackman, Lindsey R. Jankowski, Makinzie N. Hamilton, Brian P. Ziemba, Julie A. Reisz, Angelo D'Alessandro, L. Madden Brewster, Christopher A. DeSouza, Zhiying You, Michel Chonchol, E. Fiona Bailey, Douglas R. Seals
Summary: The study showed that high-resistance inspiratory muscle strength training can improve blood pressure and endothelial function in middle-aged and older adults with high blood pressure, while also enhancing NO bioavailability and reducing reactive oxygen species activity. It is a safe and highly adherable lifestyle intervention for this population.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Review
Biochemistry & Molecular Biology
Cristobal avila, Jose Ignacio Vinay, Marzia Arese, Luciano Saso, Ramon Rodrigo
Summary: Infertility is a common condition that affects a significant percentage of couples worldwide, with male infertility being a prominent cause. Oxidative stress has been increasingly recognized as a key factor in male infertility, but effective antioxidant interventions have not yet been established.
Review
Cardiac & Cardiovascular Systems
Vittorio Emanuele Bianchi
HEART FAILURE REVIEWS
(2018)
Article
Endocrinology & Metabolism
V. E. Bianchi, V. Locatelli
Review
Cardiac & Cardiovascular Systems
Vittorio Emanuele Bianchi
CURRENT PROBLEMS IN CARDIOLOGY
(2020)
Article
Clinical Neurology
Vittorio E. Bianchi, William G. Herbert, Jonathan Myers, Paul M. Ribisl, Larry E. Miller, Ronald L. Dalman
SLEEP AND BREATHING
(2015)
Review
Neurosciences
Vittorio Emanuele Bianchi, Pomares Fredy Herrera, Rizzi Laura
Summary: Neurodegenerative diseases are characterized by the loss of neurons in the brain, and nutrition plays a crucial role in their pathogenesis and development. The Mediterranean diet, nutritional support, and calorie-controlled diets have a protective effect against cognitive decline and diseases like Alzheimer's and Parkinson's, while malnutrition and insulin resistance are significant risk factors.
NUTRITIONAL NEUROSCIENCE
(2021)
Review
Cardiac & Cardiovascular Systems
Vittorio Emanuele Bianchi
HEART FAILURE REVIEWS
(2020)
Review
Andrology
Vittorio Emanuele Bianchi
Summary: Alzheimer's disease is a neurodegenerative disease influenced by sex hormones. Animal models have shown that testosterone can protect neurons by reducing amyloid-beta production, improving synaptic signaling, and preventing neuronal death. Studies have found that prostate cancer patients receiving androgen deprivation therapy have a higher incidence of dementia and Alzheimer's disease. Testosterone therapy in hypogonadal men with Alzheimer's disease and cognitive impairment has shown some positive results.
WORLD JOURNAL OF MENS HEALTH
(2022)
Review
Neurosciences
Vittorio Emanuele Bianchi, Laura Rizzi, Fahad Somaa
Summary: This article reviews the relationship between nutrition and Parkinson's disease (PD) in elderly patients. The effects of malnutrition and the Mediterranean diet (MeDiet) on the incidence and progression of PD have been studied, and interventions such as nutritional correction, regulation of gut microbiota, and following the MeDiet have been found to reduce the onset and clinical progression of PD. Polyphenols, polyunsaturated fatty acids, and coffee intake may have a protective effect, while milk and its accessory products may increase the risk of PD. Nutritional intervention is essential for improving clinical outcomes and reducing disease progression in PD.
NUTRITIONAL NEUROSCIENCE
(2023)
Review
Cardiac & Cardiovascular Systems
Vittorio Emanuele Bianchi, Stephan von Haehling
Summary: Chronic anemia is a significant risk factor for mortality in heart failure patients, and restoring physiological levels of hemoglobin is essential. Nutritional deficits, iron deficiency, chronic kidney disease, inflammation, and hormonal imbalances are contributing factors to chronic anemia. Hormonal therapy and exercise have shown potential in improving hemoglobin levels and clinical outcomes.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Review
Endocrinology & Metabolism
Vittorio Emanuele Bianchi, Laura Rizzi, Elena Bresciani, Robert J. Omeljaniuk, Antonio Torsello
JOURNAL OF THE ENDOCRINE SOCIETY
(2020)
Letter
Cardiac & Cardiovascular Systems
Vittorio Emanuele Bianchi
Review
Nutrition & Dietetics
Vittorio Emanuele Bianchi
CLINICAL NUTRITION ESPEN
(2016)
Review
Endocrinology & Metabolism
Vittorio Emanuele Bianchi
JOURNAL OF THE ENDOCRINE SOCIETY
(2019)
Review
Nutrition & Dietetics
Vittorio Emanuele Bianchi
CLINICAL NUTRITION ESPEN
(2018)