Article
Biochemistry & Molecular Biology
Paulo H. C. Mesquita, Donald A. Lamb, Joshua S. Godwin, Shelby C. Osburn, Bradley A. Ruple, Johnathon H. Moore, Christopher G. Vann, Kevin W. Huggins, Andrew D. Fruge, Kaelin C. Young, Andreas N. Kavazis, Michael D. Roberts
Summary: The study found that 6 weeks of resistance training reduced oxidative damage and increased antioxidant enzyme activities in skeletal muscle of older adults. The responses of older adults to resistance training involve multi-level control (transcriptional, post-transcriptional, and post-translational) of the redox status of skeletal muscle.
Article
Psychiatry
Gianluca Pandolfo, Giovanni Genovese, Antonio Bruno, Domenica Campolo, Valeria Tigano, Mariateresa Cristani, Marco Casciaro, Giovanni Pioggia, Sebastiano Gangemi
Summary: The pathophysiology of schizophrenia is still not well understood. Genetic factors and oxidative stress play key roles in its development and progression. Oxidative stress leads to the continuous production of oxidation products, such as AGEs and AOPPs, which interact with their receptors, amplifying the production of reactive oxygen species (ROS) and pro-inflammatory cytokines. In this study, plasma levels of AGEs and AOPPs were found to be significantly higher in schizophrenia patients compared to controls, confirming their involvement in mental disorders. Antioxidant nutraceuticals and a healthy lifestyle could reduce oxidative stress and alleviate schizophrenia symptoms.
PSYCHIATRY RESEARCH
(2022)
Review
Food Science & Technology
Hiba N. Rajha, Armelle Paule, Gerard Aragones, Mariana Barbosa, Carla Caddeo, Esperance Debs, Rada Dinkova, Gunter P. Eckert, Ariel Fontana, Prisca Gebrayel, Richard G. Maroun, Alessandra Napolitano, Lucia Panzella, Giulio Maria Pasinetti, Jan F. Stevens, Andreas Schieber, Marvin Edeas
Summary: Polyphenols have attracted researchers from various disciplines due to their diverse biological activities. The latest scientific research has focused on polyphenol interactions with the microbiome and mitochondria, as well as their potential applications in cosmetics, dietary supplements, and functional foods. Polyphenols may play a key role in disease prevention and have promising prospects in future food and nutrition.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Review
Nutrition & Dietetics
Sen-Yuan Hong, Bao-Long Qin
Summary: Urolithiasis is a common urological disease with increasing prevalence and high recurrence rates worldwide. Reactive oxygen species (ROS) and oxidative stress (OS) play crucial roles in stone formation. Dietary polyphenols, which are natural antioxidant compounds found in plant-based foods and beverages, have been shown to be effective in preventing and treating stone formation. This review discusses the antioxidant potential of polyphenols and their mechanisms in ameliorating oxidative stress and preventing stone formation. Dietary polyphenols offer promising applications in the treatment and prevention of urolithiasis.
Article
Biochemistry & Molecular Biology
Jeane Martinha dos Anjos Cordeiro, Luciano Cardoso Santos, Luciana Santos de Oliveira, Bianca Reis Santos, Emilly Oliveira Santos, Erikles Maceedo Barbosa, Isabela Oliveira de Macedo, Gustavo Jose Cote de Fretilas, Daniel de Assis Santos, Mario Sergio lima de Lavor, Juneo Freitas Silva
Summary: Maternal hypothyroidism is associated with pre-eclampsia and intrauterine growth restriction due to oxidative stress and endoplasmic reticulum stress in the placenta. This study found that hypothyroidism affects fetal-placental development and leads to oxidative stress and endoplasmic reticulum stress at the maternal-fetal interface in rats.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Jovan Rudic, Vladimir Jakovljevic, Nikola Jovic, Maja Nikolic, Jasmina Sretenovic, Slobodanka Mitrovic, Sergey Bolevich, Stefani Bolevich, Miroslav Mitrovic, Sasa Raicevic, Kristina Andric, Andjela Dimkic Milenkovic, Dejana Rakic, Jovana Joksimovic Jovic
Summary: This study investigated the isolated and synergistic effects of standardized Aronia melanocarpa extract (SEA) and metformin (MET) in alleviating reproductive and metabolic abnormalities in polycystic ovary syndrome (PCOS). The findings showed that SEA alone or in combination with MET could improve the PCOS rat model, restoring oxidative stress parameters and ameliorating reproductive and metabolic disturbances.
Review
Biochemistry & Molecular Biology
Laura Sabatino
Summary: Thyroid hormones (TH) play an important role in regulating metabolism and energy demand. However, excessive oxidation caused by uncontrolled oxidants can lead to oxidative stress and various diseases. The nuclear factor erythroid 2-related factor (Nrf2) is a key player in maintaining the balance between oxidants and antioxidants in the TH system. This review explores the relationship between Nrf2-related pathways and TH-associated conditions, including the cardioprotective role of TH mediated by Nrf2.
Article
Veterinary Sciences
Sina Salavati, Asghar Mogheiseh, Saeed Nazifi, Atefeh Amiri, Behrooz Nikahval
Summary: This study found that administering melatonin to dogs before and after ovariohysterectomy can increase antioxidant enzyme concentrations and decrease oxidative stress levels.
BMC VETERINARY RESEARCH
(2021)
Article
Environmental Sciences
Sonalin Rath, Surajit Das
Summary: Bacteria thriving in the mangrove ecosystem play a significant role in elemental cycles, but their performance is influenced by climate change and environmental stressors. This study investigates the genotoxic effect of such stressors on mangrove bacteria and their adaptation strategies. The results show cellular injuries and DNA damage in response to stressors, with different bacterial strains exhibiting varying levels of tolerance and adaptive mechanisms.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Lucas Eduardo Moreira Abadia, Alex Rodrigues Gomes, Italo Nascimento Freitas, Abraao Tiago Batista Guimaraes, Boniek Gontijo Vaz, Mohamed Ahmed Ibrahim Ahmed, Thiarlen Marinho da Luz, Aline Sueli de Lima Rodrigues, Guilherme Malafaia
Summary: This study evaluated the effects of plastic microfibers, organic compounds, and heavy metals on mound-building termites. The results showed that animals in the roadside area were more contaminated and experienced increased oxidative stress and cholinesterase effects. The study highlights the importance of further investigation and attention to the pollution of roadside soils.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemistry & Molecular Biology
Ashley S. Nemec-Bakk, Sarah Niccoli, Caitlund Davidson, Danika Roy, Lisa Stoa, Shayenthiran Sreetharan, Alain Simard, Douglas R. Boreham, Joanna Y. Wilson, T. C. Tai, Simon J. Lees, Neelam Khaper
Summary: The study found that low-dose radiation during late gestation may affect glucose uptake and oxidative stress in female offspring.
Review
Biochemistry & Molecular Biology
Irma Virant-Klun, Senka Imamovic-Kumalic, Bojana Pinter
Summary: Exposure to endocrine-disrupting chemicals can lead to oxidative stress and disruption of the endocrine system, affecting human reproduction and development. This review examines the association between endocrine disruptors and oxidative stress-related male infertility. It finds that bisphenols and phthalates have detrimental effects on semen quality and sperm DNA integrity.
Article
Biochemistry & Molecular Biology
Eleonora Cremonini, Elena Daveri, Dario E. Iglesias, Jiye Kang, Ziwei Wang, Russell Gray, Angela Mastaloudis, Colin D. Kay, Shelly N. Hester, Steven M. Wood, Cesar G. Fraga, Patricia Oteiza
Summary: This study investigated the effects of a cyanidin-and delphinidin-rich extract on the postprandial dysmetabolism, inflammation, and insulin signaling triggered by a high fat meal. The results showed that the extract reduced the negative effects associated with postprandial dysmetabolism and regulated glycemia and lipidemia.
Article
Pharmacology & Pharmacy
Veronica F. Salau, Ochuko L. Erukainure, Kolawole A. Olofinsan, Recardia L. S. Schoeman, Motlalepula G. Matsabisa
Summary: The study investigated the hepatoprotective effect of Lippia javanica herbal tea in Fe2+-mediated hepatic oxidative injury. Results showed that the infusion has strong antioxidant activity and hepatoprotective effects. It increased the levels of reduced glutathione, non-protein thiol, superoxide dismutase, and catalase, while reducing hepatic malondialdehyde levels and several enzyme activities. The infusion contains phytoconstituents such as phenolic compounds, tannins, phenolic glycosides, and terpenoids. Molecular docking analysis revealed the potential binding affinity of dihydroroseoside and obacunone with antioxidant enzymes. Overall, the study highlights the potential therapeutic use of L. javanica herbal tea in oxidative stress-related liver diseases.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Plant Sciences
Amit Kumar, Mohammad Israil Ansari, Pradyumna Kumar Singh, Abu Baker, Kiran Gupta, Sudhakar Srivastava
Summary: Arsenic is a toxic element, but its stress can be mitigated by selenium and silica supplementation. This study found that the combined application of arsenic, selenium, and silica can reduce arsenic accumulation in rice plants and enhance their tolerance to arsenic stress.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Article
Biochemistry & Molecular Biology
Ana Morales, Barbara Frei, Casey Leung, Rodger Titman, Shannon Whelan, Z. Morgan Benowitz-Fredericks, Kyle H. Elliott
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2020)
Article
Ecology
Bao-Jun Sun, Christopher Huebner, Lisa A. Treidel, Rebecca M. Clark, Kevin T. Roberts, G. J. Kenagy, Caroline M. Williams
FUNCTIONAL ECOLOGY
(2020)
Article
Endocrinology & Metabolism
J. W. Simkins, A. E. Joseph, F. Bonier, Z. M. Benowitz-Fredericks
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2020)
Article
Biology
Kathryn Wilsterman, Mattina M. Alonge, Darcy K. Ernst, Cody Limber, Lisa A. Treidel, George E. Bentley
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2020)
Article
Behavioral Sciences
Shannon Whelan, Scott A. Hatch, Z. M. Benowitz-Fredericks, Charline Parenteau, Olivier Chastel, Kyle H. Elliott
Summary: The current study investigated the relationship between food supply, energy balance, and the timing of breeding in income-breeding animals. Results showed that increased food supply advanced endocrine and laying phenology, while net energy balance had little impact on energy reserves.
HORMONES AND BEHAVIOR
(2021)
Article
Biology
Lisa A. Treidel, Rebecca M. Clark, Melissa T. Lopez, Caroline M. Williams
Summary: Animals adjust resource acquisition to meet changing physiological demands throughout life. Variations in physiological demands, determined by sex and life history strategy, impact nutritional targets and tissue allocation.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2021)
Article
Ecology
Lisa A. Treidel, Gessen S. Quintanilla Ramirez, Dillon J. Chung, Michael A. Menze, Jose P. Vazquez-Medina, Caroline M. Williams
Summary: Life history and metabolism are interconnected, and dispersal capability and maximal metabolic rates play important roles in this relationship. Selection on flight capability drives the evolution of metabolic capacities, particularly in tissues powering locomotion at the cellular and organelle levels.
JOURNAL OF EVOLUTIONARY BIOLOGY
(2022)
Article
Biology
Z. M. Benowitz-Fredericks, L. M. Lacey, S. Whelan, A. P. Will, S. A. Hatch, A. S. Kitaysky
Summary: Determinants of individual variation in resource allocation are linked to somatic state, which affects short-term physiological and behavioral responses as well as long-term fitness implications.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Physiology
Lisa A. Treidel, Priyanka Goswami, Caroline M. Williams
Summary: Mitochondria play a critical role in cellular energy production and metabolic processes, and variations in mitochondrial function are often associated with variations in life histories within and across species. This study investigates whether differences in mitochondrial function related to life history are fixed or result from flexible changes in metabolism throughout the life cycle. The results show that mitochondrial oxidative phosphorylation capacity increases in the fat body tissue of long-winged crickets throughout early adulthood, indicating flexibility in mitochondrial function specific to alternative life histories. These findings suggest that tissue-specific functional constraints may underlie the trade-off between flight and oogenesis.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2023)
Article
Evolutionary Biology
Marcella Sozzoni, Joan Ferrr Obiol, Giulio Formenti, Anna Tigano, Josephine R. Paris, Jennifer R. Balacco, Nivesh Jain, Tatiana Tilley, Joanna Collins, Ying Sims, Jonathan Wood, Z. Morgan Benowitz-Fredericks, Kenneth A. Field, Eyuel Seyoum, Marie Claire Gatt, Don-Jean Leandri-Breton, Chinatsu Nakajima, Shannon Whelan, Luca Gianfranceschi, Scott A. Hatch, Kyle H. Elliott, Akiko Shoji, Jacopo G. Cecere, Erich D. Jarvis, Andrea Pilastro, Diego Rubolini
Summary: Amidst the current biodiversity crisis, genomic resources for declining species can offer valuable insights into population decline factors. This study presents a high-quality chromosome-level reference genome for the black-legged kittiwake, which will enable further studies on the impacts of global change on this species.
GENOME BIOLOGY AND EVOLUTION
(2023)
Meeting Abstract
Zoology
Sierra Pete, Alexander Kitaysky, Scott Hatch, Z. Morgan Benowitz-Fredericks
INTEGRATIVE AND COMPARATIVE BIOLOGY
(2023)
Meeting Abstract
Zoology
S. E. Lynn, Z. M. Benowitz-Fredericks
INTEGRATIVE AND COMPARATIVE BIOLOGY
(2021)
Meeting Abstract
Zoology
Z. M. Benowitz-Fredericks, L. M. Lacey, S. Whelan, A. P. Will, S. A. Hatch, A. S. Kitaysky, U. Bucknell, U. Bucknell
INTEGRATIVE AND COMPARATIVE BIOLOGY
(2021)
Meeting Abstract
Zoology
S. Whelan, S. A. Hatch, Z. M. Benowitz-Fredericks, O. Chastel, K. H. Elliott
INTEGRATIVE AND COMPARATIVE BIOLOGY
(2020)
Meeting Abstract
Zoology
K. M. Edwards, P. B. Caine, L. M. Lacey, S. A. Hatch, Z. M. Benowitz-Fredericks
INTEGRATIVE AND COMPARATIVE BIOLOGY
(2019)