Article
Anatomy & Morphology
Ugo E. Pazzaglia, Marcella Reguzzoni, Chiara Milanese, Renata Manconi, Luca Lanteri, Tiziana Cubeddu, Guido Zarattini, Piero A. Zecca, Mario Raspanti
Summary: This study compares the skeletal calcification pattern of batoid Raja asterias with mammalian Homo sapiens and teleost Xiphias gladius. Different techniques were used, including histology, histochemistry, SEM/EDAX analysis, TGA, DSC, and FTIR. The calcified cartilage of R. asterias diverges from the ossification models of H. sapiens and X. gladius, showing higher water release and more amorphous bioapatite. In R. asterias, the calcified cartilage remains un-remodeled throughout the lifespan, while in endochondral ossification, fetal calcified cartilage is replaced by bone matrix.
MICROSCOPY RESEARCH AND TECHNIQUE
(2023)
Review
Endocrinology & Metabolism
Priyanka Ramesh, Rahul Jagadeesan, Saravanan Sekaran, Anuradha Dhanasekaran, Selvaraj Vimalraj
Summary: Flavonoids are polyphenolic compounds found in various natural products with multiple applications, including anti-inflammatory, anti-oxidative, and anti-carcinogenic properties, as well as the ability to stimulate bone formation. They influence bone remodelling through various signaling pathways and play a crucial role in maintaining bone integrity and structure. Their effects on regulating angiogenesis, decreasing inflammatory cytokine levels, and scavenging reactive oxygen species further underscore their potential as a promising agent in treating bone-related ailments in the future.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Michael D. D'Emic, Patrick M. O'Connor, Riley S. Sombathy, Ignacio Cerda, Thomas R. Pascucci, David Varricchio, Diego Pol, Anjali Dave, Rodolfo A. Coria, Kristina A. Curry Rogers
Summary: In amniotes, adjustments to the rate of growth rather than its duration are considered as the primary developmental strategy underlying body size evolution. However, most previous studies lack a phylogenetic framework and focus on pairwise comparisons. Here, we present a large-scale phylogenetic comparative analysis of non-avialan theropod dinosaurs, revealing that changes in both growth rate and duration played significant roles in the evolution of body size disparity in these dinosaurs and potentially in amniotes as a whole.
Article
Endocrinology & Metabolism
Kevin F. Hoffseth, Jennifer Simkin, Emily Busse, Kennon Stewart, James Watt, Andrew Chapple, Aaron Hargrove, Mimi C. Sammarco
Summary: Bone regeneration is a critical area of research that impacts the treatment of diseases like osteoporosis and age-related bone decline. A new analysis approach based on open-source semi-automatic methods has been developed to analyze bone tissue at a granular level using mu CT image data, offering insights into structural quality and mineral distribution in regenerated bone. Results from applying this approach to mouse digits before and after amputation injury show differences in inner void fraction, patterning, mineral distribution, and density between regenerated and unamputated bone.
Article
Multidisciplinary Sciences
Brent Adrian, Heather F. Smith, Christopher R. Noto, Aryeh Grossman
Summary: The study describes a new side-necked turtle, Pleurochayah appalachius gen. et sp. nov., which is a basal member of the Bothremydidae. This discovery reveals the oldest evidence of dispersal of crown Pleurodira from Gondwana to Laurasia, and demonstrates unique marine adaptation and dispersal capability among basal bothremydids.
SCIENTIFIC REPORTS
(2021)
Article
Materials Science, Ceramics
E. K. Papynov, V. Apanasevich, N. G. Plekhova, S. Zinoviev, E. A. Kotciurbii, O. O. Shichalin, E. B. Modin, O. Korshunova, I. S. Afonin, I. O. Evdokimov, A. A. Bardin, I. Yu Buravlev, A. S. Portnyagin
Summary: This study thoroughly investigated the biocompatibility of high quality ZrO2-hydroxyapatite composite bioceramics using various techniques. The results showed efficient osteointegration of the bioceramics in rabbit cranial bone regeneration, indicating its potential as an implant material for regenerative and bone-reconstructive surgery.
CERAMICS INTERNATIONAL
(2022)
Article
Cardiac & Cardiovascular Systems
Yuya Takahashi, Takanori Yamaguchi, Toyokazu Otsubo, Kana Nakashima, Kodai Shinzato, Ryosuke Osako, Shigeki Shichida, Yuki Kawano, Akira Fukui, Atsushi Kawaguchi, Shinichi Aishima, Tsunenori Saito, Naohiko Takahashi, Koichi Node
Summary: This study aimed to histologically validate atrial structural remodelling associated with atrial fibrillation. The histological correlates of atrial structural remodelling were fibrosis, increased intercellular space, myofibrillar loss, and decreased nuclear density. Each histological component was defined using electron microscopy and immunohistochemistry studies.
EUROPEAN HEART JOURNAL
(2023)
Article
Multidisciplinary Sciences
Chang-Fu Zhou, Dongxiang Yu, Ziheng Zhu, Brian Andres
Summary: This study provides histological evidence for the ontogeny of tapejarid pterosaurs in the Jehol Biota, showing their presence in various sizes and crest states, indicating the premaxillary crest as an ontogenetic feature. The study also found that the largest skeletally immature individuals might have reached sexual maturity, with a size gap between sexual and skeletal maturity.
SCIENTIFIC REPORTS
(2022)
Review
Biochemical Research Methods
Jessica R. Crawshaw, Jennifer A. Flegg, Miguel O. Bernabeu, James M. Osborne
Summary: This review article examines the existing mathematical models of developmental vascular remodelling and discusses their contributions to the field of vascular development. It identifies four modelling paradigms and addresses future directions for each paradigm. The development of multiscale models, subcellular models, and experimental model validation are identified as major challenges for the field moving forward.
PLOS COMPUTATIONAL BIOLOGY
(2023)
Article
Biology
Christopher T. Griffin, Michelle R. Stocker, Caitlin Colleary, Candice M. Stefanic, Emily J. Lessner, Mitchell Riegler, Kiersten Formoso, Krista Koeller, Sterling J. Nesbitt
Summary: Morphology plays a crucial role in vertebrate paleontology, providing the basis for taxonomic identification and evolutionary hypotheses. Assessing maturity is essential for studying ontogenetic changes, population structure, and paleoecology in saurian reptiles, but the methodological challenges and terminological ambiguity need to be addressed. Integrating data from extant and extinct taxa, as well as using multiple lines of evidence, is crucial for improving clarity and coherence in maturity assessment among saurian reptiles.
BIOLOGICAL REVIEWS
(2021)
Article
Chemistry, Physical
Geraldine M. Jowett, Michael D. A. Norman, Tracy T. L. Yu, Patricia Rosell Arevalo, Dominique Hoogland, Suzette T. Lust, Emily Read, Eva Hamrud, Nick J. Walters, Umar Niazi, Matthew Wai Heng Chung, Daniele Marciano, Omer S. Omer, Tomasz Zabinski, Davide Danovi, Graham M. Lord, Jons Hilborn, Nicholas D. Evans, Cecile A. Dreiss, Laurent Bozec, Oommen P. Oommen, Christian D. Lorenz, Ricardo M. P. da Silva, Joana F. Neves, Eileen Gentleman
Summary: Type-1 innate lymphoid cells drive intestinal epithelial proliferation and extracellular matrix remodelling through TGF-beta 1 secretion, which could exacerbate inflammatory bowel disease comorbidities such as cancer and fibrosis.
Article
Zoology
Carmen Nacarino-Meneses, Anusuya Chinsamy
Summary: The study found that the life-history events of the African hipparionine Eurygnathohippus hooijeri were delayed, likely as an adaptation to a low adult extrinsic mortality and low juvenile survival rates, with fast bone growth possibly due to a high-quality diet and abundant water sources. Combining bone and dental histology in research is crucial for obtaining refined paleobiological information about extinct vertebrates.
ZOOLOGICAL JOURNAL OF THE LINNEAN SOCIETY
(2022)
Article
Anatomy & Morphology
Amin Agliano, P. Martin Sander, Tanja Wintrich
Summary: This study investigates the histology and microanatomy of vertebral centra inEdaphosaurus boanerges andDimetrodon, revealing similar bone tissues but slightly faster bone growth in juvenileDimetrodon. The preservation of an ossified notochord in someDimetrodon specimens sheds light on the development of intervertebral tissues and the potential effects on limb movement and locomotion. The organization of trabeculae and thickness of the vertebral cortex provide insights into the adaptation of these animals to their habitats.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY
(2021)
Article
Agricultural Engineering
Mengsu Liu, Chao Wang, Xuefeng Ren, Song Gao, Shiqin Yu, Jingwen Zhou
Summary: Resveratrol, a polyphenol with various applications, has low production yield. Researchers were able to increase resveratrol production through pathway engineering and enzyme assembly, achieving high yields.
BIORESOURCE TECHNOLOGY
(2022)
Article
Anatomy & Morphology
Ignacio A. Cerda, Fernando E. Novas, Jose Luis Carballido, Leonardo Salgado
Summary: The external morphology, internal microanatomy, and bone microstructure of the elongated hemispinous processes of dicraeosaurid sauropods were analyzed. The study found no evidence supporting the presence of a keratinized sheath covering these elongated processes, but it did support the hypothesis of a cervical sail in these dinosaurs.
JOURNAL OF ANATOMY
(2022)
Article
Anthropology
Antonio Rosas, Beatriz Losada Agustina, Daniel Garcia-Martinez, Nicole Torres-Tamayo, Antonio Garcia-Tabernero, Juan Francisco Pastor, Marco de la Rasilla, Markus Bastir
JOURNAL OF HUMAN EVOLUTION
(2020)
Article
Anthropology
Maria Giovanna Belcastro, Valentina Mariotti, Annalisa Pietrobelli, Rita Sorrentino, Antonio Garcia-Tabernero, Almudena Estalrrich, Antonio Rosas
JOURNAL OF HUMAN EVOLUTION
(2020)
Article
Ecology
Christopher J. Dunmore, Matthew M. Skinner, Ameline Bardo, Lee R. Berger, Jean-Jacques Hublin, Dieter H. Pahr, Antonio Rosas, Nicholas B. Stephens, Tracy L. Kivell
NATURE ECOLOGY & EVOLUTION
(2020)
Article
Anthropology
Almudena Estalrrich, Jose Antonio Alarcon, Antonio Rosas
JOURNAL OF HUMAN EVOLUTION
(2020)
Article
Anthropology
Almudena Estalrrich, Ana B. Marin-Arroyo
Summary: This study presents an analysis of non-masticatory dental wear modifications in deciduous dentition of Neanderthal and anatomically modern human subadult individuals, suggesting potential involvement in group activities and contribution to group welfare. These dental wear patterns support the importance of mouth involvement in paramasticatory activities throughout the Pleistocene.
JOURNAL OF HUMAN EVOLUTION
(2021)
Article
Medicine, General & Internal
Sebastien Durand, Justine Dufour, Antonio Rosas, Fabio Becce, Caley Orr
Summary: This study analyzed the geometric similarities among bipartite scaphoids from primate species with fused and unfused scaphoid centrales. The main feature of a bipartite scaphoid is the continuity along the anteroposterior axis, with the os centrale being smaller and elongated in the anteroposterior direction in all specimens. The position of the os centrale centroid compared to the scaphoid had a strong orientation along the proximodistal axis in all species.
Article
Geology
P. G. Silva, T. Bardaji, J. Baena-Preysler, J. L. Giner-Robles, J. Van der Made, C. Zazo, A. Rosas, J. Lario
Summary: The new version of the chronostratigraphic chart provides comprehensive updates and revisions for the Quaternary of the Iberian Peninsula, including recently approved GSSPs for the Holocene and Chibanian stages, as well as corrections and modifications that have arisen since then.
CUATERNARIO Y GEOMORFOLOGIA
(2021)
Article
Biology
Antonio Rosas, Antonio Garcia-Tabernero, Dario Fidalgo, Maximiliano Fero Mene, Cayetano Ebana Ebana, Fidel Esono Mba, Juan Ignacio Morales, Palmira Saladie
Summary: The African rainforest is lacking in ape fossils from the last 10 million years, but archaeological-palaeontological surveys in Equatorial Guinea have found short sedimentary sequences near river estuaries with lithic industry and charcoal remains, yet no macro vertebrate fossils. The palaeontological desert cannot be attributed to scarcity of sampling, and factors such as low sedimentation/erosion rates, scavenger action by ants and termites, and fossildiagenetic processes may contribute to the lack of fossil record in the rainforest.
HISTORICAL BIOLOGY
(2022)
Article
Anthropology
Juan Morales, Artur Cebria, Josep M. Verges, Sandra Banuls-Cardona, Josep M. Cervello, Raquel Hernando, Diego Lombao, Juan Marin, Roser Marsal, F. Xavier Oms, Jose Rabunal, Antonio Rodriguez-Hidalgo, Maria Soto, Antonio Rosas, Josep M. Fullola
Summary: This project is the first systematic study of the use of large, conglomerate caves in north-eastern Iberia among Pleistocene hunter-gatherers.
Article
Geology
Antonio Rosas, Emilia Galli, Dario Fidalgo, Antonio Garcia-tabernero, Rosa Huguet, Daniel Garcia-martinez, Pedro Pinero, Jordi Agusti, Alba Rico-barrio, Josep Vallverdu
Summary: This article describes the discovery of the Quibas Early Pleistocene site in Spain and the study of the large herbivorous mammals found there. The site belongs to the Early-Middle Pleistocene transition and is characterized by a change in orbital cyclicity, resulting in intensified climate and significant faunal turnover.
RIVISTA ITALIANA DI PALEONTOLOGIA E STRATIGRAFIA
(2022)
Article
Ecology
Almudena Estalrrich, Kristin L. L. Krueger
Summary: Studying diet and behavioral strategies of children in ancient societies through dental microwear texture analysis. Results showed similarities between Neandertal and Point Hope children, different from Amarna Egyptian children, indicating diversity in abrasive load exposure and participation in non-dietary anterior tooth-use behaviors.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2022)
Article
Anthropology
Dario Fidalgo, Antonio Rosas, Almudena Estalrrich, Antonio Garcia-Tabernero, Francisco J. Pastor, Antonio Pineda, Rosa Huguet, Isabel Caceres, Andreu Olle, Josep Vallverdu, Palmira Saladie
JOURNAL OF HUMAN EVOLUTION
(2023)
Article
Geosciences, Multidisciplinary
Juan I. Morales, Artur Cebria, Maria Soto, Antonio Rodriguez-Hidalgo, Raquel Hernando, Elena Moreno-Ribas, Diego Lombao, Jose R. Rabunal, David M. Martin-Perea, Antonio Garcia-Tabernero, Ethel Allue, Andrea Garcia-Basanta, Esther Lizano, Tomas Marques-Bonet, Sahra Talamo, Laura Tassoni, Carles Lalueza-Fox, Josep M. Fullola, Antonio Rosas
Summary: This study presents an exceptional collection of Late Pleistocene human remains from Simanya Gran, offering valuable insights into the morphology and evolutionary trajectory of hominins in the northeastern Iberian Peninsula.
FRONTIERS IN EARTH SCIENCE
(2023)
Article
Archaeology
Miguel Angel Fano, Marco de la Rasilla, Miriam Cubas
Summary: This passage discusses the origin of Mesolithic studies in Asturias, North Spain, and the independent research on Mesolithic in Cantabria and the Basque Country. It also highlights the influence of relationships between Spanish and foreign archaeologists on the study of Mesolithic.
Meeting Abstract
Anthropology
Almudena Estalrrich, Ana B. Marin-Arroyo, Lawrence G. Straus, Manuel R. Gonzalez Morales
AMERICAN JOURNAL OF BIOLOGICAL ANTHROPOLOGY
(2022)