期刊
BIOLOGICAL TRACE ELEMENT RESEARCH
卷 143, 期 2, 页码 794-802出版社
HUMANA PRESS INC
DOI: 10.1007/s12011-010-8942-4
关键词
Lead; Cadmium; Elderly; Hair; Nail; Body burden
资金
- National Research Foundation of Korea (NRF)
- Ministry of Education, Science and Technology [2009-0072222]
- National Research Foundation of Korea [2009-0072222] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Lead and cadmium are toxic to humans at excessive levels, and monitoring the human body burden of these metals is important in preventing adverse health effects. In this study, we assessed the exposure to lead and cadmium among an elderly population 60 years of age or older. Based on data from 115 participants, we found that the geometric mean lead concentrations in hair and fingernails were 1.11 mu g/g [95% confidence interval (CI) 0.78-1.58] and 1.11 mu g/g (95% CI 0.81-1.51), respectively. The lead concentrations in hair and fingernails were significantly related to cigarette smoking. The geometric mean cadmium concentrations in hair and fingernails were 52.6 ng/g (95% CI 42.0-65.9) and 40.1 ng/g (95% CI 29.9-53.9), respectively. Cadmium concentrations in hair were significantly related to body mass index and cigarette smoking, whereas higher fingernail cadmium concentrations were related to alcohol drinking. Correlations between hair and fingernail concentrations of lead and of cadmium were slightly positive. Our findings suggest that the body burden of lead and cadmium varies according to demographic factors, and hair and fingernails could be used differentially as a biological medium for metal exposure.
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