Review
Biochemistry & Molecular Biology
Marcin Wroblewski, Joanna Wroblewska, Jaroslaw Nuszkiewicz, Marta Pawlowska, Roland Wesolowski, Alina Wozniak
Summary: Impaired levels of trace elements such as selenium, zinc, copper, iron, manganese, and iodine can negatively impact the thyroid endocrine system by affecting oxidative stress and antioxidant defense. There is a limited number of studies that directly correlate trace element supplementation with the prevention or slowing down of thyroid diseases and the improvement of the antioxidant profile. However, some studies have shown that supplementation with zinc and selenium can reduce lipid peroxidation levels and improve antioxidant activity in thyroid diseases like hypothyroidism and autoimmune thyroiditis. This systematic review provides an overview of the current knowledge on the relationship between trace elements and thyroid diseases in terms of oxidoreductive homeostasis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Ida Osuchowska-Grochowska, Eliza Blicharska, Marek Gogacz, Agata Nogalska, Izabela Winkler, Agnieszka Szopa, Halina Ekiert, Barbara Tymczyna-Borowicz, Mansur Rahnama-Hezavah, Cezary Grochowski
Summary: Endometriosis is a chronic inflammatory condition that depends on estrogen, and its cause is still uncertain, possibly related to oxidative stress. Research mainly focuses on the potential role of trace elements in the disease, but more comprehensive studies are needed to confirm the role of these elements in the pathomechanism of endometriosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Endocrinology & Metabolism
Charalampia Amerikanou, Stamatia-Angeliki Kleftaki, Sotirios Karavoltsos, Dimitra Tagkouli, Aikaterini Sakellari, Evdokia Valsamidou, Aristea Gioxari, Nick Kalogeropoulos, Andriana C. Kaliora
Summary: The prevalence of obesity is increasing globally and has negative effects on the socioeconomic system. Metals and metalloids have significant effects on the immune system and metabolism, and are influenced by factors related to obesity. Further research is needed to understand the association between metals/metalloids and obesity-related metabolic abnormalities, highlighting the importance of inflammation and oxidative stress.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Kisholay Mazumdar, Suchismita Das
Summary: Centella asiatica was found to be an efficient plant for simultaneous extraction of ten trace elements from industrial effluent, showing significant reductions in toxic metals after a 28-day trial. The plant also exhibited improved growth and effective localization of metals in the roots. Additionally, phytoremediation trials with Clarias batrachus confirmed the successful reduction of metal burden in fish, suggesting its utility for bio-monitoring purposes.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Review
Biochemistry & Molecular Biology
Lichun Qiao, Xuan Liu, Yujie He, Jiaheng Zhang, Hao Huang, Wenming Bian, Mumba Mulutula Chilufya, Yan Zhao, Jing Han
Summary: Fluorine, considered essential but controversial for human health, can lead to skeletal fluorosis with symptoms of osteosclerosis and degenerative changes in joint cartilage due to long-term excessive intake. Research focuses on signaling pathways, stress pathways, and epigenetics for understanding the pathogenesis of skeletal fluorosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Environmental Sciences
Feiqing Wang, Yanju Li, Dongxin Tang, Jianing Zhao, Xu Yang, Yanqing Liu, Fengtao Peng, Liping Shu, Jishi Wang, Zhixu He, Yang Liu
Summary: This meta-analysis systematically evaluated the effects of water improvement and defluoridation in fluorosis-endemic areas in North and South China. The results showed significant reductions in dental fluorosis and skeletal fluorosis prevalence, as well as urinary fluoride levels after water improvement. Additionally, the effects were greater in South China compared to North China.
ENVIRONMENTAL POLLUTION
(2021)
Article
Biology
Feda Aljaser, Hajera Tabassum, Sabiha Fatima, Manal Abudawood, Naheed Banu
Summary: The study found that oxidative stress and trace elements have a significant impact on male infertility, with increased oxidation and lipid peroxidation in infertile men's semen, decreased antioxidant capacity, and lower levels of trace elements like zinc and magnesium. There was a significant correlation between trace elements and oxidative markers with sperm motility.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Halyna Tkachenko, Natalia Kurhaluk, Natalia Skaletska, Viktor Maksin, Zbigniew Osadowski
Summary: This study found significantly decreased levels of copper, calcium, zinc, and selenium in the blood of children with chronic fluorosis, while strontium and lead levels increased. Various elements in the blood samples of fluorosis children were lower than reference values, and TBARS levels were higher.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Yi Zhang, Yimin Fang, Shen Zhao, Jialong Wu, Chenkang Lu, Lai Jiang, Shujun Ran, Jia Wang, Fei Sun, Bin Liu
Summary: The objective of this study was to understand mouse osteoblast ferroptosis under high fluoride environment. The genetic changes and role of ferroptosis-related genes in fluoride-resistant mouse osteoblasts were analyzed using high-throughput sequencing.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Multidisciplinary Sciences
Huseyin Gunizi, Hasan Basri Savas
Summary: This study aims to investigate the relationship between complaints and serum trace element and oxidative stress levels in patients with BPPV. The study found that serum Cu levels were lower in the patient group, and Total Thiol and Native Thiol values were also lower in patients with BPPV. Disulfide values, on the other hand, were significantly higher in the disease group. The study suggests that serum oxidative stress and trace elements play a role in the pathophysiology of BPPV.
Article
Engineering, Environmental
Farwa Basit, Javaid Akhter Bhat, Mohammed Nasser Alyemeni, Tariq Shah, Parvaiz Ahmad
Summary: This research reveals the role of exogenous nitric oxide (NO) in alleviating vanadium (V)-induced phytotoxicity in soybean plants. It improves plant biomass, growth, and photosynthetic attributes by regulating carbohydrates and plants biochemical composition, and enhances guard cells and stomatal aperture of soybean leaves. NO supplementation also regulates plant hormones, phenolic profile, and detoxifies excessive V content, thereby reducing oxidative stress and enhancing crop development and production.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Magin Gonzalez-Moscoso, Antonio Juarez-Maldonado, Gregorio Cadenas-Pliego, Diana Meza-Figueroa, Bhaskar SenGupta, Nadia Martinez-Villegas
Summary: This study investigates the effect of arsenic (As) contamination on tomato plants and the potential use of silicon nanoparticles (Si NPs) to mitigate this effect. The results show that higher concentrations of As in irrigation water lead to greater uptake and translocation of As in tomato plants. However, the application of Si NPs reduces As translocation and tomato yield. The increased production of photosynthetic pigments and improved enzymatic activity suggest that Si NPs can help tomato plants adapt to high concentrations of As.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Chaoqun Qi, Hongjun Wang, Zhaoying Liu, Haibo Yang
Summary: This study analyzed the correlation between oxidative stress status and trace elements in pulmonary TB patients at the beginning and during 6 months of anti-TB treatment. The findings indicate that anti-TB treatment could reduce oxidative stress status and increase the levels of trace elements.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Alvaro Gonzalez-Dominguez, Jesus Dominguez-Riscart, Maria Millan-Martinez, Rosa Maria Mateos-Bernal, Alfonso Maria Lechuga-Sancho, Raul Gonzalez-Dominguez
Summary: Although puberty influences obesity progression, the molecular mechanisms underlying the role of sexual maturation in obesity-related complications are largely unknown. This study investigates the impact of puberty on oxidative stress, inflammation, and trace element blood levels in children with obesity. The findings suggest that pubertal development improves inflammatory and oxidative control in obese children, possibly through trace element-mediated buffering mechanisms.
Article
Agriculture, Dairy & Animal Science
Elham Valavi, Mahdieh Zaeemi, Mehrdad Mohri
Summary: This study investigated the age-related changes of thyroid hormones, serum oxidative biomarkers, and trace elements in healthy Saanen goat kids during the first three months of life. The results suggest that specific age-related reference values are essential for proper interpretation of the serum levels of thyroid hormones and manganese in these goat kids. Additionally, improving the antioxidant system during this critical period is crucial due to the high level of thyroid hormones and their relationship with oxidative biomarkers and trace elements.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2022)