Article
Medical Laboratory Technology
Aldo E. Polettini, Christoph Sauer, Martina Spiess, Wolfgang Schultis
Summary: Hair testing data analysis revealed patterns of methamphetamine abuse and significant differences in abuse levels between genders. These findings provide further clues to the association of gender and pharmacogenomics with methamphetamine metabolism.
CLINICA CHIMICA ACTA
(2022)
Article
Psychiatry
Eleonora Paolizzi, Giulio Bertamini, Arianna Bentenuto, Paola Venuti
Summary: Research found that females with ASD exhibited more synchronous behaviors in interactions, with longer, more complex, and engaging interplays that were more frequently adequately concluded. The social affect, personal-social, and language quotients in females were positively correlated with the complexity, duration, and adequacy of exchanges, while males did not show this correlation. Successful interactions seemed to rely more on social abilities in females, while males appeared to rely more on performance skills.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Psychology, Developmental
Ivar Snorrason, Emily J. Ricketts, Aliza T. Stein, Hardian Thamrin, SoJeong J. Lee, Hannah Goldberg, Yuan Hu, Throstur Bjorgvinsson
Summary: Trichotillomania (hair-pulling disorder) has a higher prevalence in females, but males are more common in early onset cases. Males present at a younger age, especially in childhood.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2022)
Article
Veterinary Sciences
Sarah van Boemmel-Wegmann, Heidrun Gehlen, Ann-Kristin Barton, Kathrin Buettner, Juergen Zentek, Nadine Passlack
Summary: Little is known about the effects of animal- and diet-related factors on the plasma zinc concentrations of horses and ponies. The study evaluated the impact of age, sex, horse type, and internal diseases on the plasma zinc concentrations in 538 equine patients. A feeding study with healthy horses and ponies assessed the effects of dietary zinc supplements on the plasma and mane hair zinc concentrations. In conclusion, plasma zinc concentrations were not significantly influenced by nutritional and non-nutritional factors, while mane hair samples better reflected the dietary zinc supply.
VETERINARY SCIENCES
(2023)
Article
Public, Environmental & Occupational Health
Sam Hugh-Jones, Anna Wilding, Luke Munford, Matt Sutton
Summary: Previous studies have shown that smoking, exercise, and social interaction play a mediating role in the relationship between physical and mental health. This study explores the effects of different mediators on the relationship between past and future physical and mental health across different age and gender groups. The results indicate that in-person social interaction is the most significant mediator in the relationship between mental health and future physical health.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Psychology, Multidisciplinary
T. Wing Lo, Cora Y. T. Hui, Xin Guan, Sharon I. Kwok
Summary: Hair regulation is an important policy in correctional institutions for maintaining hygiene, security, and discipline. This study examined the perceived influence of hairstyles on the behavioral responses of Chinese prisoners. The findings showed that male prisoners are more prone to violent tendencies, and hairstyle is associated with violent behavior in a gender-related way. Restrictive hair regulations without considering social and cultural meanings and gender differences can negatively impact male prisoners' self-esteem and increase negative emotional responses in all prisoners, while reducing their perception of procedural fairness.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Medicine, Research & Experimental
Jinfeng Peng, Jiwei Sun, Jiajia Zhao, Xuliang Deng, Fengyuan Guo, Lili Chen
Summary: ACE2 and TMPRSS2 were found to be co-expressed in the epithelial cells of oral tissues, with higher expression levels in the relatively elderly group. Male oral epithelial cells exhibited higher level of TMPRSS2.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Medicine, General & Internal
Pil Sang Song, Mi Joo Kim, Seok-Woo Seong, Si Wan Choi, Hyeon-Cheol Gwon, Seung-Ho Hur, Seung-Woon Rha, Chang-Hwan Yoon, Myung Ho Jeong, Jin-Ok Jeong
Summary: Studies on gender differences in mortality after AMI have yielded inconsistent results. This study found that young women have a significantly higher mortality rate compared to young men, while elderly women have a lower mortality hazard compared to elderly men. The interaction between gender and age was found to be significant.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Emergency Medicine
Cameron J. J. Gettel, D. Mark Courtney, Pooja Agrawal, Tracy E. E. Madsen, Craig Rothenberg, Angela M. M. Mills, Michelle D. D. Lall, Samuel M. M. Keim, Chadd K. K. Kraus, Megan L. L. Ranney, Arjun K. K. Venkatesh
Summary: This study aimed to investigate the age and number of years since residency graduation at which male and female emergency physicians exhibit attrition from the workforce. The results showed that female physicians exhibited attrition approximately 12 years younger than male physicians. These findings highlight the widespread disparities regarding attrition in the emergency medicine workforce, which need to be addressed to ensure stability, longevity, and diversity.
ACADEMIC EMERGENCY MEDICINE
(2023)
Review
Cell Biology
Sifan Wang, Yuanbo Kang, Fei Qi, Hongzhong Jin
Summary: Hair graying is an early and obvious physical trait associated with aging in humans. Recent advances in molecular biology and genetics have provided insights into the genes involved in melanin synthesis, transport, and distribution in hair follicles. This review summarizes these advancements, including enrichment theory, Genome-Wide association studies, whole exome sequencing, gene expression studies, and animal models, aiming to understand the genetic changes associated with hair graying and lay the groundwork for future research. Furthermore, understanding the genetics of hair graying is valuable in exploring potential mechanisms, treatments, or preventative measures.
AGEING RESEARCH REVIEWS
(2023)
Article
Multidisciplinary Sciences
Cristina Cabras, Kinga Kaleta, Justyna Mroz, Giorgia Loi, Cristina Sechi
Summary: This study explores gender and age differences in forgivingness using the cross-cultural and stress-and-coping perspective. The results revealed that Polish and Italian respondents did not differ in their overall tendency to forgive. However, males were found to be more forgiving than females, and older adults were more forgiving than young respondents.
Article
Psychology, Developmental
Aditi Gandotra, Renata Cserjesi, Robert Bizonics, Eszter Kotyuk
Summary: The study found that executive functions in preschool children show significant age effects in different tests, with performance improving with age. Most test results were similar to studies in other countries, indicating consistency in the structure of executive functions. Additionally, younger participants showed superior performance in cognitive flexibility tasks.
EUROPEAN JOURNAL OF DEVELOPMENTAL PSYCHOLOGY
(2021)
Article
Psychology, Developmental
Maria Sanchez, Jennifer C. Bullen, Matthew C. Zajic, Nancy McIntyre, Peter Mundy
Summary: This study examined differences in internalizing and externalizing behaviors between boys and girls diagnosed with autism spectrum disorder (ASD). Girls showed higher instances of bullying, less anger control, and poorer emotional self-control compared to boys. There were no differences between the groups in terms of social communication. Further research is needed to investigate the lesser known area of externalizing behaviors in girls with ASD.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Article
Psychology, Multidisciplinary
Yifei Li, Man Zuo, Yirong Peng, Jie Zhang, Yiping Chen, Yingxiang Tao, Biyun Ye, Jingping Zhang
Summary: The objective of this study was to investigate and analyze the awareness of gender equality, self-esteem, and subjective well-being in school-age boys and girls, as well as the factors influencing them. The results showed that there were different influential factors for boys and girls in terms of gender equality awareness, self-esteem, and subjective well-being. Children with androgynous traits were more likely to develop gender equality awareness and self-esteem.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychology, Multidisciplinary
Andrea LeFebvre, Veronika Huta
Summary: The study evaluated adults' motivations for well-being at different ages, looking at females and males separately. Four main motivations were studied: eudaimonic, hedonic pleasure, hedonic comfort, and extrinsic motivation. The findings showed that eudaimonic motivation increased for females until the 30s and did not change significantly after, while it decreased for males from the 30s to the 40s before increasing again. Hedonic pleasure decreased for both genders from the 30s onwards, with males scoring higher in the 20s.
JOURNAL OF HAPPINESS STUDIES
(2021)
Article
Medicine, Research & Experimental
Denghuang Zhan, Yongdong Ouyang, Liang Xu, Hubert Wong
Summary: The study investigated the feasibility of incorporating prior information on time effects using a Bayesian approach in a stepped-wedge cluster randomized trial, showing that this approach can help reduce the required sample size and improve the efficiency of the trial.
Article
Peripheral Vascular Disease
Laura A. Magee, Jeffrey Bone, Salwa Banoo Owasil, Joel Singer, Terry Lee, Mrutunjaya B. Bellad, Shivaprasad S. Goudar, Alexander G. Logan, Salesio E. Macuacua, Ashalata A. Mallapur, Hannah L. Nathan, Rahat N. Qureshi, Esperanca Sevene, Andrew H. Shennan, Anifa Vala, Marianne Vidler, Zulfiqar A. Bhutta, Peter von Dadelszen
Summary: In pregnancy, higher blood pressure levels and visit-to-visit variability are associated with adverse pregnancy outcomes, with each 5 mm Hg increase in blood pressure levels leading to increased odds of the composite outcome. Increased blood pressure visit-to-visit variability is also associated with increased odds of hypertension and adverse pregnancy outcomes.
Article
Emergency Medicine
David Barbic, Gary Andolfatto, Brian Grunau, Frank X. Scheuermeyer, Bill Macewan, Hong Qian, Hubert Wong, Skye P. Barbic, William G. Honer
Summary: This study compared the use of intramuscular ketamine with a combination of midazolam and haloperidol for sedating emergency department patients with severe agitation. The results showed that ketamine led to significantly shorter time to adequate sedation compared to the midazolam and haloperidol combination, although the ketamine group had a slightly higher rate of serious adverse events.
ANNALS OF EMERGENCY MEDICINE
(2021)
Article
Rheumatology
Carly E. Jones, Jolanda Cibere, Hong Qian, Honglin Zhang, Yimeng Guo, David Russell, Bruce B. Forster, Hubert Wong, John M. Esdaile, David R. Wilson
Summary: This study aimed to compare the mean delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) relaxation values in hips with bone marrow lesions (BMLs) to hips without BMLs. The results indicated that hips with BMLs are associated with early hip cartilage degeneration in the osteoarthritis disease process.
ARTHRITIS CARE & RESEARCH
(2022)
Article
Public Administration
Ziba Vaghri, Lauren De Souza
Summary: The research highlights the lack of sufficient legislation in British Columbia to support Canada's commitments to protect the rights of young children. Three legislative gaps are identified that must be addressed to meet BC's commitments under the Convention on the Rights of the Child, recommending the development of a comprehensive child protection strategy prioritizing primary prevention of violence against children.
CANADIAN PUBLIC ADMINISTRATION-ADMINISTRATION PUBLIQUE DU CANADA
(2021)
Meeting Abstract
Oncology
Joseph Ragaz, John J. Spinelli, Hong Qian, Hubert Wong, Shayan Shakeraneh, Joel Fox, Kenneth S. Wilson
Article
Orthopedics
Monther Abuhantash, Andrea Veljkovic, Kevin Wing, Oliver Gagne, Hong Qian, Hubert Wong, Hooman Sadr, Murray Penner, Alastair Younger
Summary: This study compared the long-term outcomes of open ankle arthrodesis (OAA) and arthroscopic ankle arthrodesis (AAA). The results showed that after adjusting for baseline patient characteristics, there were no significant differences in patient-reported outcome measures (PROMs) between the two techniques. However, arthroscopic surgery had a lower infection rate compared to open surgery.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2022)
Article
Orthopedics
Jacek A. Kopec, Eric C. Sayre, Jolanda Cibere, Linda C. Li, Hubert Wong, Anya Okhmatovskaia, John M. Esdaile
Summary: The study aims to investigate the impact of three strategies (weight loss, ergonomic interventions, and an exercise program) on reducing the health burden of low back pain (LBP) and developed a microsimulation model of LBP in Canada. The results showed that all three interventions could significantly reduce the disability related to LBP.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Clinical Neurology
Sue Peters, Shannon B. Lim, Mark T. Bayley, Krista Best, Louise A. Connell, Helene Corriveau, Sarah J. Donkers, Sean P. Dukelow, Tara D. Klassen, Marie-Helene Milot, Brodie M. Sakakibara, Lisa Sheehy, Hubert Wong, Jennifer Yao, Janice J. Eng
Summary: Clinical practice guidelines recommend structured, progressive protocols to improve walking after stroke. However, implementation is slow, highlighting the need for an implementation trial to enable the adoption of the protocol as standard care in stroke units.
INTERNATIONAL JOURNAL OF STROKE
(2023)
Article
Medicine, Research & Experimental
Marlena Ornowska, Hubert Wong, Yongdong Ouyang, Anish Mitra, Aaron White, Sue Willems, Jessica Wittmann, Steven Reynolds
Summary: This study aims to evaluate the impact of 4% tetrasodium ethylenediaminetetraacetic acid (EDTA) on the occurrence of central line-associated bloodstream infection, catheter occlusion, and the use of alteplase for resolving occlusion. The results of this study may lead to a change in the standard of care for CVAD locking procedures, improving patient safety and reducing healthcare costs associated with preventable CVAD complications.
Article
Orthopedics
Eric C. C. Sayre, Ali Guermazi, Savvas Nicolaou, John M. M. Esdaile, Jacek A. A. Kopec, Joel Singer, Hubert Wong, Anona Thorne, Jolanda Cibere
Summary: This study aimed to identify MRI predictors of medial, lateral and patellofemoral knee joint tenderness and patellofemoral grind. The findings revealed that medial femoral cartilage, female gender, and BMI were significant predictors of medial knee joint tenderness, while female gender was a predictor of lateral knee joint tenderness, and lateral patellar osteophytes were predictors of patellofemoral grind.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Medicine, Research & Experimental
Hubert Wong
Summary: Performing a sample size calculation for a randomized controlled trial requires specifying an assumed benefit and a target power. The belief that minimum important difference should be used in setting assumed benefit and sample size is misguided. The true power of the trial depends on the true benefit, so the assumed benefit should be a realistic estimate. Calculating sample size should focus on determining reasonable estimates of the true benefit, not on judging the magnitude of benefit as important.
Article
Public, Environmental & Occupational Health
Md. Belal Hossain, James C. Johnston, Victoria J. Cook, Mohsen Sadatsafavi, Hubert Wong, Kamila Romanowski, Mohammad Ehsanul Karim
Summary: This study investigated the link between latent tuberculosis infection (LTBI) and cardiovascular disease (CVD) risk in a low-tuberculosis-incidence setting in British Columbia. The findings showed that LTBI positivity was associated with a higher CVD risk compared to LTBI negativity, with an 8% increased risk in complete case data and a statistically significant 11% increased risk when using multiple imputation for missing confounder values. In addition, incomplete LTBI therapy was associated with a higher CVD risk, while completed therapy showed a similar risk level. These findings highlight the importance of addressing LTBI in reducing CVD risk, especially in low-incidence areas.
EPIDEMIOLOGY AND INFECTION
(2023)
Meeting Abstract
Peripheral Vascular Disease
Karen C. Tran, Laura Kuyper, Jesse Bittman, Birinder Mangat, Chad Kim Sing, Heather Lindsay, Martin Dawes, Hubert Wong, Nadia A. Khan, Meagan Y. Mak, Jennifer Corderio, Kendall Ho
JOURNAL OF HYPERTENSION
(2023)
Article
Health Care Sciences & Services
Glory Apantaku, Craig Mitton, Hubert Wong, Kendall Ho
Summary: This study assesses the cost of using the home monitoring platform (TEC4Home) for patients with heart failure (HF) compared to usual care. The results show that using TEC4Home can lead to cost savings for patients.
JMIR FORMATIVE RESEARCH
(2022)
