Article
Neurosciences
Yingxin Jia, Namasvi Jariwala, Leighton B. N. Hinkley, Srikantan Nagarajan, Karuna Subramaniam
Summary: This study used magnetoencephalography imaging to investigate brain network connectivity in patients with schizophrenia. The results showed disrupted functional connectivity in multiple frequency bands, which were associated with clinical symptoms.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Neurosciences
Dorine Van Dyck, Nicolas Deconinck, Alec Aeby, Simon Baijot, Nicolas Coquelet, Nicola Trotta, Antonin Rovai, Serge Goldman, Charline Urbain, Vincent Wens, Xavier De Tiege
Summary: This study explores the relationship between procedural sequence learning performance and prior brain resting-state functional connectivity (rsFC) in school-aged children. It also investigates the rapid changes in brain rsFC induced by sequence learning. The findings suggest that pre-learning interhemispheric rsFC within the sensorimotor network influences sequence learning and visuomotor performance in children.
Review
Neurosciences
Na Xu, Wei Shan, Jing Qi, Jianping Wu, Qun Wang
Summary: Epilepsy is a disorder characterized by abnormal electrical discharges in the brain, which can be investigated through network analysis. Resting-state functional connectivity analysis is becoming increasingly important in preoperative evaluation, and magnetoencephalography (MEG) is an ideal tool for estimating such connectivity. Studies have shown that MEG-based resting-state functional connectivity has the potential to predict postsurgical outcomes for epileptic patients.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Psychiatry
Vanteemar S. Sreeraj, Venkataram Shivakumar, Gaurav Bhalerao, Sunil Kalmady, Janardhanan C. Narayanaswamy, Ganesan Venkatasubramanian
Summary: This study used Multivariate pattern analysis (MVPA) to evaluate the changes in connectivity patterns in the brains of unmedicated schizophrenia patients after antipsychotic treatment. The results showed significant connectivity pattern changes in the left anterior cingulate and paracingulate gyri (ACC/PCG) after antipsychotic treatment, and these changes were associated with improvements in clinical symptoms.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Neuroimaging
Dorine Van Dyck, Nicolas Deconinck, Alec Aeby, Simon Baijot, Nicolas Coquelet, Nicola Trotta, Antonin Rovai, Serge Goldman, Charline Urbain, Vincent Wens, Xavier De Tiege
Summary: Children with DCD exhibit increased functional brain connectivity in visual and motor areas, but this enhancement does not impact their coordinated motor and visual perceptual abilities. Additionally, an interhemispheric compensatory process may help DCD children perform visuomotor tasks within the normal range.
NEUROIMAGE-CLINICAL
(2022)
Article
Psychology, Clinical
Lizhu Luo, Christelle Langley, Laura Moreno-Lopez, Keith Kendrick, David K. Menon, Emmanuel A. Stamatakis, Barbara J. Sahakian
Summary: This study examined the association between depressive symptoms in traumatic brain injury (TBI) patients and altered resting-state functional connectivity (rs-fc) or voxel-based morphology in brain regions involved in emotional regulation and associated with depression. The results showed a positive association between depression scores and rs-fc between limbic regions and cognitive control regions, while there was a negative association between depression scores and rs-fc between limbic and frontal regions involved in emotion regulation. These findings contribute to a better understanding of the mechanisms underlying depression following TBI and can inform treatment decisions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Neurosciences
Maxi Becker, Dimitris Repantis, Martin Dresler, Simone Kuehn
Summary: This study used behavioral and fMRI data to investigate the cognitive enhancement effects of stimulants such as methylphenidate, modafinil, and caffeine. The results showed that these stimulants can enhance memory and modulate functional connectivity between brain networks. Specifically, the frontoparietal network and default mode network were found to be affected, suggesting that these networks play a role in the cognitive enhancement mechanisms of stimulants.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Elleke Tissink, Josefin Werme, Siemon C. de Lange, Jeanne E. Savage, Yongbin Wei, Christiaan A. de Leeuw, Mats Nagel, Danielle Posthuma, Martijn P. van den Heuvel
Summary: This study explores the genetic component of structural and functional connections within resting-state networks (RSNs) and their potential impact on brain disorders. It identifies genes involved in axon guidance and synaptic functioning in the visual network, and reveals the genetic overlap between RSN-FC alterations and brain disorders.
Article
Clinical Neurology
Ludmila Kucikova, Jianmin Zeng, Carlos Munoz-Neira, Graciela Muniz-Terrera, Weijie Huang, Sarah Gregory, Craig Ritchie, John O'Brien, Li Su
Summary: The study found that genetic risk factors such as APOEe4 and MAPTA alleles are associated with decreased functional connectivity in the Default Mode Network (DMN) in early adulthood. Furthermore, APOEe4 carriers showed a correlation between connectivity and cognitive performance.
JOURNAL OF NEUROLOGY
(2023)
Article
Neurosciences
Zachery D. Morrissey, Liang Zhan, Olusola Ajilore, Alex D. Leow
Summary: Resting-state functional magnetic resonance imaging (rs-fMRI) is widely used in connectomics to study the functional relationships between brain regions, facing challenges in modeling negative correlations. The new method rest2vec uses embedding techniques to transform connectomes into low-dimensional vector spaces, aiding in understanding the functional organization of the brain.
Article
Cell Biology
Sofia Puvogel, Kris Blanchard, Barbara S. Casas, Robyn L. L. Miller, Delia Garrido-Jara, Sebastian Arizabalos, Stevens K. K. Rehen, Magdalena Sanhueza, Veronica Palma
Summary: This study investigates the neural communicational dynamics during early development in schizophrenia using hiPSCs-derived neuronal cultures. The results suggest that alterations in gene expression, functional connectivity dynamics, and hub states are present in SZ networks compared to healthy control networks.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Psychiatry
Sarah Weber, Helene Hjelmervik, Alexander R. Craven, Erik Johnsen, Rune A. Kroken, Else-Marie Loberg, Lars Ersland, Kristiina Kompus, Kenneth Hugdahl
Summary: This study found an interaction effect between hallucination severity and glutamate and gamma-aminobutyric acid concentrations in the anterior cingulate cortex, supporting the interhemispheric miscommunication theory in psychosis patients. Significant positive association between glutamate concentration and STG connectivity was observed in high-AVH group, while significant negative association between GABA concentration and STG connectivity was found in low-AVH group.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Neurosciences
Ryoki Sasaki, Sho Kojima, Naofumi Otsuru, Hirotake Yokota, Kei Saito, Hiroshi Shirozu, Hideaki Onishi
Summary: This study investigated the mechanisms of cortical connections in adult tactile perception and found that the connections within the somatosensory cortex and between different somatosensory cortices are related to tactile spatial acuity. This is the first study to demonstrate the functional support of specific cortical networks for tactile spatial acuity.
Article
Neurosciences
Fei Jiang, Huaqing Jin, Yijing Gao, Xihe Xie, Jennifer Cummings, Ashish Raj, Srikantan Nagarajan
Summary: This article introduces a novel framework called TVDN for studying dynamic resting state functional connectivity. The framework includes a generative model and an inference algorithm that can automatically and adaptively learn the low-dimensional manifold of dynamic RSFC and detect dynamic state transitions in data. Experimental results demonstrate that TVDN is able to accurately capture the dynamics of brain activity and more robustly detect brain state switching.
Article
Neurosciences
Zhihong Lan, Shoujun Xu, Xiangrong Yu, Zhenjie Yu, Meng Li, Feng Chen, Yu Liu, Tianyue Wang, Yunfan Wu, Yungen Gan, Guihua Jiang
Summary: This study investigates the functional connectivity in single-sex children with autism spectrum disorders (ASDs) through resting-state functional magnetic resonance imaging (rs-fMRI), revealing enhanced connectivity in specific brain regions. The study suggests a possible relationship between atypical visual attention and poor learning ability in subjects with ASD.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Rehabilitation
Pierre Nicolo, Cecile Magnin, Elena Pedrazzini, Gijs Plomp, Anais Mottaz, Armin Schnider, Adrian G. Guggisberg
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2018)
Article
Behavioral Sciences
Aurelie L. Manuel, Nicolas Nicastro, Armin Schnider, Adrian G. Guggisberg
Article
Neurosciences
Aurelie L. Manuel, Adrian G. Guggisberg, Raphael Theze, Francesco Turri, Armin Schnider
Letter
Clinical Neurology
Pierre Nicolo, Cecile Magnin, Elena Pedrazzini, Anh Nguyen-Danse, Adrian G. Guggisberg
Article
Psychiatry
Raphael Theze, Aurelie L. Manuel, Elena Pedrazzini, Fabrice Chantraine, Maria Cristina Patru, Louis Nahum, Adrian G. Guggisberg, Armin Schnider
SCHIZOPHRENIA RESEARCH
(2019)
Correction
Neurosciences
A. L. Manuel, A. G. Guggisberg, R. Theze, F. Turri, A. Schnider
Review
Clinical Neurology
Martina Coscia, Maximilian J. Wessel, Ujwal Chaudary, Jose del R. Millan, Silvestro Micera, Adrian Guggisberg, Philippe Vuadens, John Donoghue, Niels Birbaumer, Friedhelm C. Hummel
Review
Clinical Neurology
Adrian G. Guggisberg, Philipp J. Koch, Friedhelm C. Hummel, Cathrin M. Buetefisch
CLINICAL NEUROPHYSIOLOGY
(2019)
Article
Clinical Neurology
Tomas Ros, Stefanie Enriquez-Geppert, Vadim Zotev, Kymberly D. Young, Guilherme Wood, Susan Whitfield-Gabrieli, Feng Wan, Patrik Vuilleumier, Francois Vialatte, Dimitri Van de Ville, Doron Todder, Tanju Surmeli, James S. Sulzer, Ute Strehl, Maurice Barry Sterman, Naomi J. Steiner, Bettina Sorger, Surjo R. Soekadar, Ranganatha Sitaram, Leslie H. Sherlin, Michael Schoenenberg, Frank Scharnowski, Manuel Schabus, Katya Rubia, Agostinho Rosa, Miriam Reiner, Jaime A. Pineda, Christian Paret, Alexei Ossadtchi, Andrew A. Nicholson, Wenya Nan, Javier Minguez, Jean-Arthur Micoulaud-Franchi, David M. A. Mehler, Michael Luhrs, Joel Lubar, Fabien Lotte, David E. J. Linden, Jarrod A. Lewis-Peacock, Mikhail A. Lebedev, Ruth A. Lanius, Andrea Kuebler, Cornelia Kranczioch, Yury Koush, Lilian Konicar, Simon H. Kohl, Silivia E. Kober, Manousos A. Klados, Camille Jeunet, T. W. P. Janssen, Rene J. Huster, Kerstin Hoedlmoser, Laurence M. Hirshberg, Stephan Heunis, Talma Hendler, Michelle Hampson, Adrian G. Guggisberg, Robert Guggenberger, John H. Gruzelier, Rainer W. Gobel, Nicolas Gninenko, Alireza Gharabaghi, Paul Frewen, Thomas Fovet, Thalia Fernandez, Carlos Escolano, Ann-Christine Ehlis, Renate Drechsler, R. Christopher deCharms, Stefan Debener, Dirk De Ridder, Eddy J. Davelaar, Marco Congedo, Marc Cavazza, Marinus H. M. Breteler, Daniel Brandeis, Jerzy Bodurka, Niels Birbaumer, Olga M. Bazanova, Beatrix Barth, Panagiotis D. Bamidis, Tibor Auer, Martijn Arns, Robert T. Thibault
Article
Clinical Neurology
Dung A. Nguyen-Danse, Shobana Singaravelu, Lea A. S. Chauvigne, Anais Mottaz, Leslie Allaman, Adrian G. Guggisberg
Summary: Functional connectivity (FC) assessment with EEG currently requires high-density montages and long preparation time. This study investigated reconstructing source FC with a low-density EEG montage, finding that beamformers outperformed other methods in capturing neural correlates of motor behavior.
Article
Clinical Neurology
Leslie Allaman, Anais Mottaz, Adrian G. Guggisberg
Summary: Patients with HFVDs show reduced spontaneous alpha-band interactions compared to healthy controls, suggesting that this may be a better indicator of the severity of HFVDs.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Clinical Neurology
Philip Egger, Giorgia G. Evangelista, Philipp J. Koch, Chang-Hyun Park, Laura Levin-Gleba, Gabriel Girard, Elena Beanato, Jungsoo Lee, Christine Choirat, Adrian G. Guggisberg, Yun-Hee Kim, Friedhelm C. Hummel
Summary: The study explores the role of rich-club in poststroke recovery through network-theoretical quantification of lesions in patients with ischemic stroke. Results indicate that smaller lesions focusing on the rich-club can be just as devastating as larger lesions that do not, emphasizing the importance of the rich-club in functional communication within brain networks and recovery from stroke.
Editorial Material
Clinical Neurology
Camille Farcy, Vera Moliadze, Frauke Nees, Gesa Hartwigsen, Adrian G. Guggisberg
Article
Neurosciences
Leslie Allaman, Anais Mottaz, Andreas Kleinschmidt, Adrian G. Guggisberg
JOURNAL OF NEUROSCIENCE
(2020)
Article
Behavioral Sciences
Olga Trofimova, Anais Mottaz, Leslie Allaman, Lea A. S. Chauvigne, Adrian G. Guggisberg
NEUROBIOLOGY OF LEARNING AND MEMORY
(2020)
Review
Neurosciences
Maya Jammoul, Dareen Jammoul, Kevin K. Wang, Firas Kobeissy, Ralph G. Depalma
Summary: This article reviews the possible mechanisms by which traumatic brain injury (TBI) may stimulate the development of opioid use disorder (OUD) and discusses the interaction between these two processes. CNS damage due to TBI appears to drive adverse effects of subsequent OUD, with pain being a risk factor for opioid use after TBI.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Danusa Mar Arcego, Jan-Paul Buschdorf, Nicholas O'Toole, Zihan Wang, Barbara Barth, Irina Pokhvisneva, Nirmala Arul Rayan, Sachin Patel, Euclides Jose de Mendonca Filho, Patrick Lee, Jennifer Tan, Ming Xuan Koh, Chu Ming Sim, Carine Parent, Randriely Merscher Sobreira de Lima, Andrew Clappison, Kieran J. O'Donnell, Carla Dalmaz, Janine Arloth, Nadine Provencal, Elisabeth B. Binder, Josie Diorio, Patricia Pelufo Silveira, Michael J. Meaney
Summary: This study investigates the impact of environmental influences on mental health by integrating transcriptomic data from animal models with human data. The results suggest that hippocampal glucocorticoid-related transcriptional activity mediates the effects of early adversity on neural mechanisms implicated in psychiatric disorders.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Milenna T. van Dijk, Ardesheer Talati, Pratik Kashyap, Karan Desai, Nora C. Kelsall, Marc J. Gameroff, Natalie Aw, Eyal Abraham, Breda Cullen, Jiook Cha, Christoph Anacker, Myrna M. Weissman, Jonathan Posner
Summary: This study found that maternal stress is associated with future depressive symptoms and alterations in microstructure of the dentate gyrus (DG) in offspring. These results were consistent across two independent cohorts.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Josephine C. McGowan, Liliana R. Ladner, Claire X. Shubeck, Juliana Tapia, Christina T. LaGamma, Amanda Anqueira-Gonzalez, Ariana DeFrancesco, Briana K. Chen, Holly C. Hunsberger, Ezra J. Sydnor, Ryan W. Logan, Tzong-Shiue Yu, Steven G. Kernie, Christine A. Denny
Summary: Traumatic brain injury (TBI) leads to fear generalization by altering fear memory traces, and this symptom can be improved with (R,S)-ketamine.
BIOLOGICAL PSYCHIATRY
(2024)