期刊
BIOLOGICAL CHEMISTRY
卷 395, 期 6, 页码 631-639出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/hsz-2013-0289
关键词
cytoglobin; globin; neuroglobin; nitric oxide; nitric oxide dioxygenation; nitrite
资金
- National Institutes of Health [HL098032, HL096973, DK085852]
- Institute for Transfusion Medicine
- Hemophilia Center of Western Pennsylvania
- Competitive Medical Research Fund of the UPMC Health System
Globin proteins are ubiquitous in living organisms and carry out a variety of functions related to the ability of their prosthetic heme group to bind gaseous ligands, such as oxygen, nitric oxide (NO), and CO. Moreover, they catalyze important reactions with nitrogen oxide species, such as NO dioxygenation and nitrite reduction. The formation of NO from nitrite is a reaction catalyzed by globins that has received increasing attention due to its potential as a hypoxic NO signaling mechanism. In this review, we revisit the current knowledge about the role of globins in NO formation and its physiological implications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据