Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts

Procathepsin L secretion, which triggers tumour progression, is regulated by Rab4a in human melanoma cells

(2011) Alice Barbarin et al.   BIOCHEMICAL JOURNAL

Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry

(2011) Oliver Schilling et al.   Nature Protocols

Proteomic techniques and activity-based probes for the system-wide study of proteolysis

(2010) Ulrich auf dem Keller et al.   BIOCHIMIE

Impaired turnover of autophagolysosomes in cathepsin L deficiency

(2010) Julia Dennemärker et al.   BIOLOGICAL CHEMISTRY

Biological role of matrix metalloproteinases: a critical balance

(2010) S. Loffek et al.   EUROPEAN RESPIRATORY JOURNAL

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

(2010) V. Gocheva et al.   GENES & DEVELOPMENT

Cathepsin X-deficient Gastric Epithelial Cells in Co-culture with Macrophages

(2010) Anja Bernhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiplex N-terminome Analysis of MMP-2 and MMP-9 Substrate Degradomes by iTRAQ-TAILS Quantitative Proteomics

(2010) Anna Prudova et al.   MOLECULAR & CELLULAR PROTEOMICS

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

(2010) Oded Kleifeld et al.   NATURE BIOTECHNOLOGY

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice

(2010) L. Sevenich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of epithelial cell-derived periostin in TGF-  activation, collagen production, and collagen gel elasticity in asthma

(2010) S. S. Sidhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative analysis of the secretome of TGF-β signaling-deficient mammary fibroblasts

(2010) Baogang J. Xu et al.   PROTEOMICS

Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions

(2009) Silvia Jordans et al.   BMC BIOCHEMISTRY

The multifaceted role of periostin in tumorigenesis

(2009) Kai Ruan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Identification of Five Candidate Lung Cancer Biomarkers by Proteomics Analysis of Conditioned Media of Four Lung Cancer Cell Lines

(2009) Chris Planque et al.   MOLECULAR & CELLULAR PROTEOMICS

Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics

(2009) Paul J Boersema et al.   Nature Protocols

MEROPS: the peptidase database

(2009) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis

(2009) J Dennemärker et al.   ONCOGENE

Periostin Is Required for Maturation and Extracellular Matrix Stabilization of Noncardiomyocyte Lineages of the Heart

(2008) Paige Snider et al.   CIRCULATION RESEARCH

Periostin regulates atrioventricular valve maturation

(2008) Russell A. Norris et al.   DEVELOPMENTAL BIOLOGY

Major Role of Cathepsin L for Producing the Peptide Hormones ACTH, β-Endorphin, and α-MSH, Illustrated by Protease Gene Knockout and Expression

(2008) Lydiane Funkelstein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3β signaling

(2008) Qizhu Tang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

(2008) Oliver Schilling et al.   NATURE BIOTECHNOLOGY