Inhibitory effects of three-component hybrid liposomes containing cationic lipids without drugs on the growth of human renal tumor cells in vitro

The inhibitory effects of three-component hybrid liposomes (HL) containing cationic lipids on the growth of human renal tumor cells were examined. Fifty percent inhibitory concentration of the three-component HL was remarkably reduced compared with that of dimyristolphosphatidylcholine liposomes. The induction of apoptosis by the three-component HL without antitumor drugs was obtained for human renal tumor cells for the first time in this study.