The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5

Lrp5 regulation of bone mass and serotonin synthesis in the gut

(2014) Aruna Kode et al.   NATURE MEDICINE

Reply to Lrp5 regulation of bone mass and gut serotonin synthesis

(2014) Yajun Cui et al.   NATURE MEDICINE

Romosozumab in Postmenopausal Women with Low Bone Mineral Density

(2014) Michael R. McClung et al.   NEW ENGLAND JOURNAL OF MEDICINE

The DAN family: Modulators of TGF-β signaling and beyond

(2014) Kristof Nolan et al.   PROTEIN SCIENCE

Developments in Sclerostin Biology: Regulation of Gene Expression, Mechanisms of Action, and Physiological Functions

(2014) Megan M. Weivoda et al.   Current Osteoporosis Reports

ReversingLRP5-Dependent Osteoporosis andSOSTDeficiency-Induced Sclerosing Bone Disorders by Altering WNT Signaling Activity

(2013) Ming-Kang Chang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin

(2013) Joachim Albers et al.   JOURNAL OF CELL BIOLOGY

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Sclerostin Inhibition Reverses Skeletal Fragility in an Lrp5-Deficient Mouse Model of OPPG Syndrome

(2013) R. Kedlaya et al.   Science Translational Medicine

Role of sclerostin in bone and cartilage and its potential as a therapeutic target in bone diseases

(2013) E. Michael Lewiecki   Therapeutic Advances in Musculoskeletal Disease

Mechanotransduction in bone tissue: The A214V and G171V mutations in Lrp5 enhance load-induced osteogenesis in a surface-selective manner

(2012) Paul J. Niziolek et al.   BONE

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

The way Wnt works: Components and mechanism

(2012) Kenyi Saito-Diaz et al.   GROWTH FACTORS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

High-bone-mass-producing mutations in the Wnt signaling pathway result in distinct skeletal phenotypes

(2011) Paul J. Niziolek et al.   BONE

Bone Overgrowth-associated Mutations in theLRP4Gene Impair Sclerostin Facilitator Function

(2011) Olivier Leupin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lrp5 functions in bone to regulate bone mass

(2011) Yajun Cui et al.   NATURE MEDICINE

BoneJ: Free and extensible bone image analysis in ImageJ

(2010) Michael Doube et al.   BONE

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells

(2010) Jochen Schulze et al.   JOURNAL OF BONE AND MINERAL RESEARCH

PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling

(2010) Yumie Rhee et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteocyte Wnt/ -Catenin Signaling Is Required for Normal Bone Homeostasis

(2010) I. Kramer et al.   MOLECULAR AND CELLULAR BIOLOGY

Negative Regulation of Bone Formation by the Transmembrane Wnt Antagonist Kremen-2

(2010) Jochen Schulze et al.   PLoS One

Lrp4, a Novel Receptor for Dickkopf 1 and Sclerostin, Is Expressed by Osteoblasts and Regulates Bone Growth and Turnover In Vivo

(2009) Hong Y. Choi et al.   PLoS One

The Binding Between Sclerostin and LRP5 is Altered by DKK1 and by High-Bone Mass LRP5 Mutations

(2008) Wendy Balemans et al.   CALCIFIED TISSUE INTERNATIONAL

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

(2008) Vijay K. Yadav et al.   CELL

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH