Editorial Material
Oncology
Raphael Colle, Thierry Andre, Yves Menu
Summary: The article highlights that early tumor shrinkage and depth of response predict prognosis in colorectal cancer patients treated with immune checkpoint inhibitors, but no cases of pseudoprogression were observed. Discrepancies with other studies may be due to differences in radiological evaluation criteria and timing of imaging.
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
Letter
Environmental Sciences
Davy Vanham, Mesfin M. Mekonnen
Summary: The reliability of the scarcity-weighted water footprint (WSF) and its counterproductivity for achieving SDG target 6.4 is questioned. The analysis shows that unsustainably produced wheat may receive better ranking than sustainably produced wheat based on WSF. The suggestion is to use the water stress indicator instead of WSF in the LCA framework.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Letter
Computer Science, Interdisciplinary Applications
Gangan Prathap
Summary: The study introduces an agent-based model based on a 3DSI model of scientific impact, which assumes that citations follow a mixture distribution of the rich-get-richer rule and sheer chance.
Article
Forestry
Faizah N. Alenezi, Ali Chenari Bouket, Hafsa Cherif-Silini, Allaoua Silini, Marcel Jaspars, Tomasz Oszako, Lassaad Belbahri
Summary: The Aneurinibacillus migulanus (A. migulanus) strains Nagano and NCTC 7096 have been proven to be powerful biocontrol agents against plant diseases. The cyclic peptide gramicidin S (GS) produced by both strains plays a major role in inhibiting bacteria and fungus-like organisms. A mutant of the Nagano strain impaired in GS biosynthesis showed a total loss of biocontrol ability, highlighting the importance of GS in the biocontrol potential of A. migulanus Nagano strain.
Letter
Oncology
Ciro Franzese, Ausilia Teriaca, Armando De Virgilio, Giuseppe Mercante, Giuseppe Spriano, Marta Scorsetti
Summary: Authors respond to the letter from C Franzese et al. regarding the role of radiotherapy in oligometastatic head and neck cancer.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2022)
Letter
Oncology
Abigail Goodman, Jose Velazquez-Vega, Jeffrey Olson
Summary: This study reviewed the WHO 2021 Classification of Tumors of the Central Nervous System terminology to determine the applicable components for updating the guideline on progressive glioblastoma. The research concluded that glioblastoma, IDH-wildtype WHO grade 4 is the closest category to the tumors referred to as glioblastoma in the 2016 WHO classification. As a result, this term was chosen to replace glioblastoma in the updated guideline on the role of neuropathology in managing progressive glioblastoma.
JOURNAL OF NEURO-ONCOLOGY
(2022)
Letter
Biotechnology & Applied Microbiology
J. Kevin Yin, Stephanie Pepin, Robertus van Aalst, Matthew M. Loiacono, Sandrine I. Samson
Summary: The article challenges the recommendation of high-dose influenza vaccine and criticizes the authors of inaccurate numbers-needed-to-vaccinate (NNV) calculation. It emphasizes the importance of preferential recommendation for vaccines preventing influenza/complications and considering the impact of vaccination within the context of disease burden. To address the threat of the COVID-19 pandemic, the article suggests implementing concomitant influenza/COVID-19 vaccination to reduce the burden of co-circulation of influenza and SARS-CoV-2 viruses and increase vaccine coverage as per the WHO mandate.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Biotechnology & Applied Microbiology
Johnna Perdrizet, Carlos Felipe S. Santana, Thais Senna, Rodrigo Fernandes Alexandre, Rodrigo Sini de Almeida, Julia Spinardi, Matt Wasserman
Summary: This communication addresses and clarifies the questions and criticisms raised by Gomez and colleagues regarding the assumptions and potential negative impacts of our model on decision-making in Brazil.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Letter
Audiology & Speech-Language Pathology
Nathan Keates
Summary: The purpose of this letter is to address interpretations and potential missteps in Bambara et al.'s (2021) study. It emphasizes the value of teaching skills desired by autistic individuals, while pointing out the lack of acknowledgment of the double empathy problem and the exclusive reliance on neurotypical interpretation and communication style.
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH
(2022)
Letter
Virology
Liyang Zhao, Yusi Li, Wenjuan Yi, Kuo Yan, Chao Yang, Sridhar Radhakrishnan, Rui Li, Ruirong Tan, Gang Fan, Mengyuan Dai, Miao Liu, Ning-Yi Shao
Summary: Although smoking might increase the risk of severe COVID-19, our previous study did not find strong evidence to support this conclusion. We also acknowledged that patients with diabetes or other chronic diseases could have worse outcomes in COVID-19, but this aspect was not investigated in our study as we had published separate research on diabetes. Due to limited sample size and medical records, our study could not encompass multiple factors. Nonetheless, we hope our study serves as a useful and meaningful pilot study for future research.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Oncology
Niloofar Faraji, Shahab Aali, Mahsa Motiei, Sahand Sadat Mansouri
Summary: The role of large language models (LLM) in medical and biomedical sciences is important, and AI models like ChatGPT have the potential to assist in research and clinical practice. However, it is crucial to recognize that these models should be used in conjunction with human expertise and judgment, and not as a replacement for the knowledge and experience of healthcare professionals and researchers in the field.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Letter
Computer Science, Interdisciplinary Applications
Antonio Fernandez-Cano
Summary: This paper discusses the current phenomenon of "publish or perish" in academia, highlighting the consequences and questioning the role of scientific journals and the effectiveness of peer review. It calls for improvements in the field of scientific information and communication.
Editorial Material
Oncology
Giovanni Fuca, Francesca Corti, Filippo Pietrantonio
Summary: The timing of disease re-assessment may influence the incidence of pseudoprogression, with early assessments being associated with higher incidence. These dynamics should be considered when interpreting the efficacy of treatment.
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
Article
Geography, Physical
Paul D. Bons, Tamara de Riese, Steven Franke, Maria-Gema Llorens, Till Sachau, Nicolas Stoll, Ilka Weikusat, Julien Westhoff, Yu Zhang
Summary: The research suggests that a potential hotspot on the Northeast Greenland Ice Stream (NEGIS) requires an exceptionally high heat flux to initiate or control, which would be unique in the world.
Letter
Gastroenterology & Hepatology
Per Cajander, Taher Omari, Harry Scheinin, Mika Scheinin, Johanna Savilampi
Summary: It is important to consider the impact of anesthetic agents on esophageal function testing. Dexmedetomidine has been found to affect primary peristalsis in esophageal manometry, and in the case reports by Toaz et al., secondary peristalsis during FLIP panometry was also affected. This may be due to a specific pharmacodynamic effect, with a transient direct alpha 2-mediated effect on esophageal smooth muscle, associated with a high plasma concentration before sympathetic inhibition begins.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Mathematical & Computational Biology
Anne-Laure Boulesteix, Silke Janitza, Roman Hornung, Philipp Probst, Hannah Busen, Alexander Hapfelmeier
BIOMETRICAL JOURNAL
(2019)
Article
Mathematical & Computational Biology
Simon Klau, Marie-Laure Martin-Magniette, Anne-Laure Boulesteix, Sabine Hoffmann
BIOMETRICAL JOURNAL
(2020)
Review
Genetics & Heredity
Anne-Laure Boulesteix, Marvin N. Wright, Sabine Hoffmann, Inke R. Koenig
Review
Biochemical Research Methods
Riccardo De Bin, Anne-Laure Boulesteix, Axel Benner, Natalia Becker, Willi Sauerbrei
BRIEFINGS IN BIOINFORMATICS
(2020)
Article
Obstetrics & Gynecology
D. -M Burgmann, K. Foerster, M. Klemme, M. Delius, C. Huebener, R. Wiskott, A. L. Boulesteix, A. W. Flemmer
Summary: This study evaluated the frequency, duration, and severity of desaturations and bradycardia in the first hours of life in term neonates. The results showed that approximately 30% of infants experienced desaturations, with 25% of them being prolonged desaturations. Infants born by planned Cesarean section had a significantly higher occurrence of desaturations compared to other modes of delivery.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Oncology
Daniel Samaga, Roman Hornung, Herbert Braselmann, Julia Hess, Horst Zitzelsberger, Claus Belka, Anne-Laure Boulesteix, Kristian Unger
RADIATION ONCOLOGY
(2020)
Article
Mathematics, Interdisciplinary Applications
Nicole Ellenbach, Anne-Laure Boulesteix, Bernd Bischl, Kristian Unger, Roman Hornung
Summary: The paper discusses the reasons why prediction rules trained on high-dimensional data do not generalize well across different sources, introduces a new method for tuning parameter selection, and concludes through a large-scale comparison study that tuning on external data and robust tuning with a tuned robustness parameter lead to better generalizing prediction rules.
JOURNAL OF CLASSIFICATION
(2021)
Article
Statistics & Probability
Mathias Fuchs, Roman Hornung, Anne-Laure Boulesteix, Riccardo De Bin
JOURNAL OF STATISTICAL PLANNING AND INFERENCE
(2020)
Article
Medicine, General & Internal
Anne-Laure Boulesteix, Rolf H. H. Groenwold, Michal Abrahamowicz, Harald Binder, Matthias Briel, Roman Hornung, Tim P. Morris, Jorg Rahnenfuhrer, Willi Sauerbrei
Article
Multidisciplinary Sciences
Sabine Hoffmann, Felix Schoenbrodt, Ralf Elsas, Rory Wilson, Ulrich Strasser, Anne-Laure Boulesteix
Summary: This paper presents a general framework on sources of uncertainty in computational analyses that lead to multiplicity of analysis strategies, and applies it to various approaches proposed in different disciplines to address this issue.
ROYAL SOCIETY OPEN SCIENCE
(2021)
Article
Biotechnology & Applied Microbiology
Stefan Buchka, Alexander Hapfelmeier, Paul P. Gardner, Rory Wilson, Anne-Laure Boulesteix
Summary: Many research articles claim that new data analysis methods outperform existing ones, but the veracity of such claims is questionable. This manuscript discusses the consequences of optimistic bias in evaluating novel data analysis methods, and quantitatively investigates this bias using an example from epigenetic analysis.
Article
Public, Environmental & Occupational Health
Simon Klau, Sabine Hoffmann, Chirag J. Patel, John P. A. Ioannidis, Anne-Laure Boulesteix
Summary: The study highlights the significant impact of sampling, model, and measurement uncertainty on the stability of observational associations, potentially leading to large variability in results. Measurement error in observational studies can attenuate the true effect in most cases, but may also occasionally result in overestimation.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Korbinian Lackermair, Stefan Brunner, Mathias Orban, Sven Peterss, Martin Orban, Hans D. Theiss, Bruno C. Huber, Gerd Juchem, Frank Born, Anne-Laure Boulesteix, Axel Bauer, Maximilian Pichlmaier, Joerg Hausleiter, Steffen Massberg, Christian Hagl, Sabina P. W. Guenther
Summary: This pilot study showed that randomized studies with ECLS in CS patients are feasible and safe. Small numbers of included patients impede meaningful conclusions about mortality and neurological outcome. Our findings of numerical differences in mortality and survival with severe neurological impairment give an urgent call for larger multi-centric randomized trials assessing the endpoint of all-cause mortality but also considering the effects on neurological outcome measures.
CLINICAL RESEARCH IN CARDIOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Lukas M. Weber, Wouter Saelens, Robrecht Cannoodt, Charlotte Soneson, Alexander Hapfelmeier, Paul P. Gardner, Anne-Laure Boulesteix, Yvan Saeys, Mark D. Robinson
Article
Automation & Control Systems
Philipp Probst, Anne-Laure Boulesteix, Bernd Bischl
JOURNAL OF MACHINE LEARNING RESEARCH
(2019)
