Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP

Caspase-3 feeds back on caspase-8, Bid and XIAP in type I Fas signaling in primary mouse hepatocytes

(2012) Karine Sá Ferreira et al.   APOPTOSIS

How Information Theory Handles Cell Signaling and Uncertainty

(2012) M. D. Brennan et al.   SCIENCE

The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells

(2011) Hongyun Tang et al.   BMC BIOLOGY

Combined modality therapy with TRAIL or agonistic death receptor antibodies

(2011) Hope M. Amm et al.   CANCER BIOLOGY & THERAPY

Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2−:H2O2 Ratio and Confers Anoikis Resistance to Tumors

(2011) Pengcheng Zhu et al.   CANCER CELL

Cisplatin Restores TRAIL Apoptotic Pathway in Glioblastoma-Derived Stem Cells through Up-regulation of DR5 and Down-regulation of c-FLIP

(2011) Lijuan Ding et al.   CANCER INVESTIGATION

TRAIL receptor signaling and therapeutics

(2010) Junaid Abdulghani et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

LY303511 Enhances TRAIL Sensitivity of SHEP-1 Neuroblastoma Cells via Hydrogen Peroxide-Mediated Mitogen-Activated Protein Kinase Activation and Up-regulation of Death Receptors

(2009) K. Shenoy et al.   CANCER RESEARCH

Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1

(2009) Yong Zuo et al.   CELL RESEARCH

Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP

(2009) Tae-Jin Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modeling of tumor growth and anticancer effects of combination therapy

(2009) Gilbert Koch et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Caspase-8 and its inhibitors in RCCs in vivo: the prominent role of ARC

(2008) Sebastian Heikaus et al.   APOPTOSIS

Model-based analysis of interferon-β induced signaling pathway

(2008) Jaroslaw Smieja et al.   BIOINFORMATICS

Resveratrol Induces Apoptosis through ROS-Dependent Mitochondria Pathway in HT-29 Human Colorectal Carcinoma Cells

(2008) M. Emília Juan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

(2008) John G. Albeck et al.   MOLECULAR CELL

Role of S-nitrosylation in apoptosis resistance and carcinogenesis

(2008) Anand Krishnan V. Iyer et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway

(2008) S Wang   ONCOGENE

Modeling a Snap-Action, Variable-Delay Switch Controlling Extrinsic Cell Death

(2008) John G Albeck et al.   PLOS BIOLOGY

Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression

(2007) Vladimir N. Ivanov et al.   EXPERIMENTAL CELL RESEARCH

Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP

(2007) Yeoun Hee Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE