Small-molecule inhibitor starting points learned from protein–protein interaction inhibitor structure
出版年份 2012 全文链接
标题
Small-molecule inhibitor starting points learned from protein–protein interaction inhibitor structure
作者
关键词
-
出版物
BIOINFORMATICS
Volume 28, Issue 6, Pages 784-791
出版商
Oxford University Press (OUP)
发表日期
2012-01-01
DOI
10.1093/bioinformatics/btr717
参考文献
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- (2011) Grzegorz M. Popowicz et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- KFC2: A knowledge-based hot spot prediction method based on interface solvation, atomic density, and plasticity features
- (2011) Xiaolei Zhu et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Systematic Analysis of Helical Protein Interfaces Reveals Targets for Synthetic Inhibitors
- (2010) Andrea L. Jochim et al. ACS Chemical Biology
- Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery
- (2010) Stéphanie Pérot et al. DRUG DISCOVERY TODAY
- Finding a short and accurate decision rule in disjunctive normal form by exhaustive search
- (2010) Peter R. Rijnbeek et al. MACHINE LEARNING
- Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication
- (2010) Frauke Christ et al. Nature Chemical Biology
- ANCHOR: a web server and database for analysis of protein-protein interaction binding pockets for drug discovery
- (2010) L. M. C. Meireles et al. NUCLEIC ACIDS RESEARCH
- Atomic Analysis of Protein-Protein Interfaces with Known Inhibitors: The 2P2I Database
- (2010) Raphaël Bourgeas et al. PLoS One
- The Overlap of Small Molecule and Protein Binding Sites within Families of Protein Structures
- (2010) Fred P. Davis et al. PLoS Computational Biology
- Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques
- (2009) Ryan Brenke et al. BIOINFORMATICS
- Identification of computational hot spots in protein interfaces: combining solvent accessibility and inter-residue potentials improves the accuracy
- (2009) Nurcan Tuncbag et al. BIOINFORMATICS
- Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket
- (2009) Kent D. Stewart et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods
- (2009) Stefano Lise et al. BMC BIOINFORMATICS
- Atomic Interactions and Profile of Small Molecules Disrupting Protein-Protein Interfaces: the TIMBAL Database
- (2009) Alícia P. Higueruelo et al. Chemical Biology & Drug Design
- A feature-based approach to modeling protein–protein interaction hot spots
- (2009) Kyu-il Cho et al. NUCLEIC ACIDS RESEARCH
- Comprehensive in silico mutagenesis highlights functionally important residues in proteins
- (2008) Y. Bromberg et al. BIOINFORMATICS
- Small molecular weight protein–protein interaction antagonists—an insurmountable challenge?
- (2008) Alexander Dömling CURRENT OPINION IN CHEMICAL BIOLOGY
- Predicting druggable binding sites at the protein–protein interface
- (2008) Jonathan C. Fuller et al. DRUG DISCOVERY TODAY
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