Network analyses in systems pharmacology

JNets: Exploring networks by integrating annotation

(2009) Jamie I MacPherson et al.   BMC BIOINFORMATICS

Disease candidate gene identification and prioritization using protein interaction networks

(2009) Jing Chen et al.   BMC BIOINFORMATICS

Generating Genome-Scale Candidate Gene Lists for Pharmacogenomics

(2009) N T Hansen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Identifying Network of Drug Mode of Action by Gene Expression Profiling

(2009) Francesco Iorio et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Global Versus Local Centrality in Evolution of Yeast Protein Network

(2009) Alexander E. Vinogradov   JOURNAL OF MOLECULAR EVOLUTION

Drug Discovery Using Chemical Systems Biology: Identification of the Protein-Ligand Binding Network To Explain the Side Effects of CETP Inhibitors

(2009) Li Xie et al.   PLoS Computational Biology

Evolutionary rates and centrality in the yeast gene regulatory network

(2009) Richard Jovelin et al.   GENOME BIOLOGY

Walking the Interactome for Prioritization of Candidate Disease Genes

(2008) Sebastian Köhler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Identifying gene-disease associations using centrality on a literature mined gene-interaction network

(2008) A. Ozgur et al.   BIOINFORMATICS

Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance

(2008) Karthik Raman et al.   BMC MICROBIOLOGY

Construction of a cancer-perturbed protein-protein interaction network for discovery of apoptosis drug targets

(2008) Liang-Hui Chu et al.   BMC Systems Biology

Identification of Information Flow-Modulating Drug Targets: A Novel Bridging Paradigm for Drug Discovery

(2008) W-C Hwang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Network topology determines dynamics of the mammalian MAPK1,2 signaling network: bifan motif regulation of C-Raf and B-Raf isoforms by FGFR and MC1R

(2008) Melissa Muller et al.   FASEB JOURNAL

Estimating novel potential drug targets of Plasmodium falciparum by analysing the metabolic network of knock-out strains in silico

(2008) Segun Fatumo et al.   INFECTION GENETICS AND EVOLUTION

Drug targets for tumorigenesis: Insights from structural analysis of EGFR signaling network

(2008) Saliha Durmuş Tekir et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Quantifying the Relationships among Drug Classes

(2008) Jérôme Hert et al.   Journal of Chemical Information and Modeling

Pharmacogenomics of Cardiovascular Pharmacology: Pharmacogenomic Network of Cardiovascular Disease Models

(2008) Toshio Tanaka et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

A protein interaction network associated with asthma

(2008) Sohyun Hwang et al.   JOURNAL OF THEORETICAL BIOLOGY

Betweenness centrality in a weighted network

(2008) Huijuan Wang et al.   PHYSICAL REVIEW E

Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth

(2008) K. D. Bromberg et al.   SCIENCE

Drug Target Identification Using Side-Effect Similarity

(2008) M. Campillos et al.   SCIENCE

A global view of drug-therapy interactions

(2008) Jose C Nacher et al.   BMC Pharmacology & Toxicology