期刊
BIOINFORMATICS
卷 24, 期 20, 页码 2418-2419出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btn443
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资金
- National Institutes of Health [R21-HD051835]
There are thousands of strongly conserved non-coding elements (CNEs) in vertebrate genomes, and their functions remain largely unknown. However, without biologically relevant criteria for prioritizing them, selecting a particular CNE sequences to study can be haphazard. To address this problem, we present cneViewer-a database and webtool that systematizes information on conserved non-coding DNA elements in zebrafish. A key feature here is the ability to search for CNEs that may be relevant to tissue-specific gene regulation, based on known developmental expression patterns of nearby genes. cneViewer provides this and other organizing features that significantly facilitate experimental design and CNE analysis.
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