标题
RNA-binding proteins as molecular links between cancer and neurodegeneration
作者
关键词
RNA-binding proteins, RNA metabolism, Cancer, Neurodegeneration
出版物
BIOGERONTOLOGY
Volume 15, Issue 6, Pages 587-610
出版商
Springer Nature
发表日期
2014-09-18
DOI
10.1007/s10522-014-9531-2
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Staurosporine Induced Apoptosis Rapidly Downregulates TDP-43 in Glioma Cells
- (2014) Yi-Nan Nan et al. Asian Pacific Journal of Cancer Prevention
- Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB
- (2014) Michihiro Hashimoto et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
- (2014) Haiyan Qiu et al. JOURNAL OF CLINICAL INVESTIGATION
- Selective interactions of hnRNP M isoforms with the TET proteins TAF15 and TLS/FUS
- (2014) Marija Marko et al. MOLECULAR BIOLOGY REPORTS
- DNA damage: RNA-binding proteins protect from near and far
- (2014) Martin Dutertre et al. TRENDS IN BIOCHEMICAL SCIENCES
- ARHGEF28 gene exon 6/intron 6 junction mutations in Chinese amyotrophic lateral sclerosis cohort
- (2014) Yan Ma et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- ADAR2 editing activity in newly diagnosed versus relapsed pediatric high-grade astrocytomas
- (2013) Sara Tomaselli et al. BMC CANCER
- A multifunctional protein EWS regulates the expression of Drosha and microRNAs
- (2013) K Y Kim et al. CELL DEATH AND DIFFERENTIATION
- The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation
- (2013) Rossella Lucá et al. EMBO Molecular Medicine
- ALS/FTLD-linked TDP-43 regulates neurite morphology and cell survival in differentiated neurons
- (2013) Jeong-Ho Han et al. EXPERIMENTAL CELL RESEARCH
- A conserved N-terminal motif is required for complex formation between FUS, EWSR1, TAF15 and their oncogenic fusion proteins
- (2013) Christer Thomsen et al. FASEB JOURNAL
- A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma
- (2013) Tim Hon Man Chan et al. GUT
- Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520
- (2013) Yun-Yong Park et al. HEPATOLOGY
- The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage
- (2013) Adam S. Mastrocola et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress
- (2013) Reddy Ranjith K. Sama et al. JOURNAL OF CELLULAR PHYSIOLOGY
- TDP-43 associates with stalled ribosomes and contributes to cell survival during cellular stress
- (2013) Shinji Higashi et al. JOURNAL OF NEUROCHEMISTRY
- Posttranscriptional regulation of SOD1 gene expression under oxidative stress: Potential role of ELAV proteins in sporadic ALS
- (2013) Pamela Milani et al. NEUROBIOLOGY OF DISEASE
- Inverse occurrence of cancer and Alzheimer disease: A population-based incidence study
- (2013) M. Musicco et al. NEUROLOGY
- Cytoplasmic expression of the ELAV-like protein HuR as a potential prognostic marker in esophageal squamous cell carcinoma
- (2013) Cong Zhang et al. TUMOR BIOLOGY
- ADAR1 is essential for intestinal homeostasis and stem cell maintenance
- (2013) W Qiu et al. Cell Death & Disease
- ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
- (2013) Yueqin Zhou et al. PLoS Genetics
- Detection of a novel frameshift mutation and regions with homozygosis within ARHGEF28 gene in familial amyotrophic lateral sclerosis
- (2013) Cristian A. Droppelmann et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism
- (2012) Brian A. Keller et al. ACTA NEUROPATHOLOGICA
- Evolutionary Origin of RNA Editing
- (2012) Michael W. Gray BIOCHEMISTRY
- The association between cancer and amyotrophic lateral sclerosis
- (2012) D. Michal Freedman et al. CANCER CAUSES & CONTROL
- A-to-I editing of protein coding and noncoding RNAs
- (2012) Arka Mallela et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment
- (2012) Mariangela Morlando et al. EMBO JOURNAL
- Loss of fused in sarcoma (FUS) promotes pathological Tau splicing
- (2012) Denise Orozco et al. EMBO REPORTS
- Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
- (2012) Julien Couthouis et al. HUMAN MOLECULAR GENETICS
- Motoneurons Secrete Angiogenin to Induce RNA Cleavage in Astroglia
- (2012) A. Skorupa et al. JOURNAL OF NEUROSCIENCE
- Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma
- (2012) Sophie Postel-Vinay et al. NATURE GENETICS
- Rho guanine nucleotide exchange factor is an NFL mRNA destabilizing factor that forms cytoplasmic inclusions in amyotrophic lateral sclerosis
- (2012) Cristian A. Droppelmann et al. NEUROBIOLOGY OF AGING
- ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis
- (2012) F Galeano et al. ONCOGENE
- TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs
- (2012) M Ballarino et al. ONCOGENE
- Rgnef (p190RhoGEF) Knockout Inhibits RhoA Activity, Focal Adhesion Establishment, and Cell Motility Downstream of Integrins
- (2012) Nichol L. G. Miller et al. PLoS One
- HuR Is Necessary for Mammary Epithelial Cell Proliferation and Polarity at Least in Part via ΔNp63
- (2012) Wensheng Yan et al. PLoS One
- Identification of Novel Deregulated RNA Metabolism-Related Genes in Non-Small Cell Lung Cancer
- (2012) Iñaki Valles et al. PLoS One
- Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions
- (2012) Jenny Blechingberg et al. PLoS One
- TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
- (2012) Y. Kawahara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The ADAR protein family
- (2012) Yiannis A Savva et al. GENOME BIOLOGY
- Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis
- (2011) N. Ticozzi et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Low-Grade Fibromyxoid Sarcoma
- (2011) Harry L. Evans AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
- (2011) Michael A. van Es et al. ANNALS OF NEUROLOGY
- A fraction of the transcription factor TAF15 participates in interactions with a subset of the spliceosomal U1 snRNP complex
- (2011) Michael Leichter et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations
- (2011) Manuela Neumann et al. BRAIN
- Autoantibody signatures as biomarkers to distinguish prostate cancer from benign prostatic hyperplasia in patients with increased serum prostate specific antigen
- (2011) Dennis J. O'Rourke et al. CLINICA CHIMICA ACTA
- TDP-43 and FUS/TLS: sending a complex message about messenger RNA in amyotrophic lateral sclerosis?
- (2011) Michael J. Strong et al. FEBS Journal
- mRNA and protein levels of FUS, EWSR1, and TAF15 are upregulated in liposarcoma
- (2011) Jessica I. Spitzer et al. GENES CHROMOSOMES & CANCER
- Emerging role of angiogenin in stress response and cell survival under adverse conditions
- (2011) Shuping Li et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Nucleolar proteins with altered expression in leukemic cell lines
- (2011) Kaisa J. Teittinen et al. LEUKEMIA RESEARCH
- The RNA-Binding Protein HuR Promotes Glioma Growth and Treatment Resistance
- (2011) N. Filippova et al. MOLECULAR CANCER RESEARCH
- The Ewing Sarcoma Protein Regulates DNA Damage-Induced Alternative Splicing
- (2011) Maria Paola Paronetto et al. MOLECULAR CELL
- Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation
- (2011) Pavel Ivanov et al. MOLECULAR CELL
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
- (2011) Magdalini Polymenidou et al. NATURE NEUROSCIENCE
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons
- (2011) Takuto Hideyama et al. NEUROBIOLOGY OF DISEASE
- FUS/TLS Is a Co-Activator of Androgen Receptor in Prostate Cancer Cells
- (2011) Simon Haile et al. PLoS One
- Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner
- (2011) H.-L. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A yeast functional screen predicts new candidate ALS disease genes
- (2011) J. Couthouis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 pathology in sporadic ALS occurs in motor neurons lacking the RNA editing enzyme ADAR2
- (2010) Hitoshi Aizawa et al. ACTA NEUROPATHOLOGICA
- Human low molecular weight neurofilament (NFL) mRNA interacts with a predicted p190RhoGEF homologue (RGNEF) in humans
- (2010) Kathryn Volkening et al. Amyotrophic Lateral Sclerosis
- Linking cell polarity, aging and rejuvenation
- (2010) Arie Budovsky et al. BIOGERONTOLOGY
- Ewing sarcoma gene Ews regulates hematopoietic stem cell senescence
- (2010) J. Cho et al. BLOOD
- FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth
- (2010) G. N. Brooke et al. CANCER RESEARCH
- De novo truncating FUS gene mutation as a cause of sporadic amyotrophic lateral sclerosis
- (2010) Mariely DeJesus-Hernandez et al. HUMAN MUTATION
- Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly
- (2010) Mohamed M. Emara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes
- (2010) Chantelle F. Sephton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyotrophic Lateral Sclerosis-associated Proteins TDP-43 and FUS/TLS Function in a Common Biochemical Complex to Co-regulate HDAC6 mRNA
- (2010) Sang Hwa Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A neuroprotective role for angiogenin in models of Parkinson’s disease
- (2010) Trent U. Steidinger et al. JOURNAL OF NEUROCHEMISTRY
- Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
- (2010) Y.-F. Xu et al. JOURNAL OF NEUROSCIENCE
- Multiplex SILAC Analysis of a Cellular TDP-43 Proteinopathy Model Reveals Protein Inclusions Associated with SUMOylation and Diverse Polyubiquitin Chains
- (2010) Nicholas T. Seyfried et al. MOLECULAR & CELLULAR PROTEOMICS
- HuR Uses AUF1 as a Cofactor To Promote p16INK4 mRNA Decay
- (2010) N. Chang et al. MOLECULAR AND CELLULAR BIOLOGY
- RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability
- (2010) S. J. Cho et al. NUCLEIC ACIDS RESEARCH
- Recent advances in the molecular pathogenesis of Ewing's sarcoma
- (2010) E C Toomey et al. ONCOGENE
- ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
- (2010) S.-C. Ling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
- (2010) Hans Wils et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer and Neurodegeneration: Between the Devil and the Deep Blue Sea
- (2010) Hélène Plun-Favreau et al. PLoS Genetics
- Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease
- (2009) Manuela Neumann et al. ACTA NEUROPATHOLOGICA
- FUS pathology in basophilic inclusion body disease
- (2009) David G. Munoz et al. ACTA NEUROPATHOLOGICA
- A new subtype of frontotemporal lobar degeneration with FUS pathology
- (2009) M. Neumann et al. BRAIN
- Neamine Inhibits Prostate Cancer Growth by Suppressing Angiogenin-Mediated rRNA Transcription
- (2009) S. Ibaragi et al. CLINICAL CANCER RESEARCH
- ADAR1 and ADAR2 Expression and Editing Activity during Forebrain Development
- (2009) Michelle M. Jacobs et al. DEVELOPMENTAL NEUROSCIENCE
- Human U1 snRNA forms a new chromatin-associated snRNP with TAF15
- (2009) Laure Jobert et al. EMBO REPORTS
- Large-scale mRNA sequencing determines global regulation of RNA editing during brain development
- (2009) H. Wahlstedt et al. GENOME RESEARCH
- Ectopic expression of CGG containing mRNA is neurotoxic in mammals
- (2009) V. Hashem et al. HUMAN MOLECULAR GENETICS
- Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis
- (2009) G. S. Pesiridis et al. HUMAN MOLECULAR GENETICS
- Amyotrophic Lateral Sclerosis-linked Mutant SOD1 Sequesters Hu Antigen R (HuR) and TIA-1-related Protein (TIAR)
- (2009) Liang Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Angiogenin cleaves tRNA and promotes stress-induced translational repression
- (2009) Satoshi Yamasaki et al. JOURNAL OF CELL BIOLOGY
- Fragile X syndrome: from molecular genetics to therapy
- (2009) C D'Hulst et al. JOURNAL OF MEDICAL GENETICS
- Mutations of FUS gene in sporadic amyotrophic lateral sclerosis
- (2009) L. Corrado et al. JOURNAL OF MEDICAL GENETICS
- The particular relationship between Parkinson’s disease and malignancy: a focus on skin cancers
- (2009) Rivka Inzelberg et al. JOURNAL OF NEURAL TRANSMISSION
- FUS mutations in amyotrophic lateral sclerosis: clinical, pathological, neurophysiological and genetic analysis
- (2009) I. P. Blair et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery
- (2009) Brian D. Freibaum et al. JOURNAL OF PROTEOME RESEARCH
- Molecular analysis of the HuD gene in neuroendocrine lung cancers
- (2009) Vito D’Alessandro et al. LUNG CANCER
- Genomics screen in transformed stem cells reveals RNASEH2A, PPAP2C, and ADARB1 as putative anticancer drug targets
- (2009) J. M. Flanagan et al. MOLECULAR CANCER THERAPEUTICS
- DCTN1 mutations in Perry syndrome
- (2009) Matthew J Farrer et al. NATURE GENETICS
- TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations
- (2009) Satomi Maekawa et al. NEUROPATHOLOGY
- The State of Synapses in Fragile X Syndrome
- (2009) Brad E. Pfeiffer et al. NEUROSCIENTIST
- ADAR1 is required for hematopoietic progenitor cell survival via RNA editing
- (2009) R. XuFeng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
- (2009) I. Wegorzewska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- The TET Family of Proteins: Functions and Roles in Disease
- (2009) A. Y. Tan et al. Journal of Molecular Cell Biology
- A Novel Function for Fragile X Mental Retardation Protein in Translational Activation
- (2009) Elias G Bechara et al. PLOS BIOLOGY
- Enduring involvement of tau, β-amyloid, α-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism–dementia complex of Guam (ALS/PDC)
- (2008) Judith Miklossy et al. ACTA NEUROPATHOLOGICA
- Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer disease
- (2008) William T. Hu et al. ACTA NEUROPATHOLOGICA
- TDP-43A315T mutation in familial motor neuron disease
- (2008) Michael A. Gitcho et al. ANNALS OF NEUROLOGY
- Identification and characterization of FUS/TLS as a new target of ATM
- (2008) Mary Gardiner et al. BIOCHEMICAL JOURNAL
- Diverse molecular functions of Hu proteins
- (2008) M. N. Hinman et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Calcium-permeable AMPA receptors containing Q/R-unedited GluR2 direct human neural progenitor cell differentiation to neurons
- (2008) Nicholas P. Whitney et al. FASEB JOURNAL
- RNA-binding proteins and post-transcriptional gene regulation
- (2008) Tina Glisovic et al. FEBS LETTERS
- Down-regulation of RNA Editing in Pediatric Astrocytomas
- (2008) Caterina Cenci et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hu Antigen R (HuR) Functions as an Alternative Pre-mRNA Splicing Regulator of Fas Apoptosis-promoting Receptor on Exon Definition
- (2008) José M. Izquierdo JOURNAL OF BIOLOGICAL CHEMISTRY
- Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis
- (2008) Rachid Mazroui et al. JOURNAL OF CELL BIOLOGY
- Mutant copper-zinc superoxide dismutase associated with amyotrophic lateral sclerosis binds to adenine/uridine-rich stability elements in the vascular endothelial growth factor 3′-untranslated region
- (2008) Xuelin Li et al. JOURNAL OF NEUROCHEMISTRY
- Concomitant TAR-DNA-Binding Protein 43 Pathology Is Present in Alzheimer Disease and Corticobasal Degeneration but Not in Other Tauopathies
- (2008) Kunihiro Uryu et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- TAR-DNA Binding Protein 43 in Pick Disease
- (2008) Stefanie H. Freeman et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Control of Motoneuron Survival by Angiogenin
- (2008) D. Kieran et al. JOURNAL OF NEUROSCIENCE
- EWS/FLI1 suppresses retinoblastoma protein function and senescence in Ewing's sarcoma cells
- (2008) Hsien-Ming Hu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis
- (2008) Vivianna M Van Deerlin et al. LANCET NEUROLOGY
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
- (2008) Jochen C Hartner et al. NATURE IMMUNOLOGY
- Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype
- (2008) K Mazan-Mamczarz et al. ONCOGENE
- Pallidonigral TDP-43 pathology in Perry syndrome
- (2008) Christian Wider et al. PARKINSONISM & RELATED DISORDERS
- Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer
- (2008) G. Sanchez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression
- (2008) Y. M. Ayala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
- (2007) Emanuele Buratti Frontiers in Bioscience-Landmark
- Transcriptional dysregulation in a transgenic model of Parkinson disease
- (2007) Talene A. Yacoubian et al. NEUROBIOLOGY OF DISEASE
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