Article
Chemistry, Physical
Michal Bodik, Michaela Sojkova, Martin Hulman, Milan Tapajna, Martin Truchly, Karol Vegso, Matej Jergel, Eva Majkova, Marianna Spankova, Peter Siffalovic
Summary: The tribological properties of MoS2 films can be optimized by adjusting the crystallographic orientation, leading to different friction behaviors. Horizontally oriented MoS2 sheets exhibit a lower coefficient of friction compared to vertically oriented sheets.
APPLIED SURFACE SCIENCE
(2021)
Article
Multidisciplinary Sciences
Izabela Zglobicka, Juergen Gluch, Zhongquan Liao, Stephan Werner, Peter Guttmann, Qiong Li, Piotr Bazarnik, Tomasz Plocinski, Andrzej Witkowski, Krzysztof J. Kurzydlowski
Summary: The diatom shell serves as a complex siliceous structure that demonstrates the process of digging into the third dimension using modern visualization techniques. This paper highlights the importance of a comprehensive multi-length scale approach to bio-structures/materials, utilizing state-of-the-art imaging techniques to gain deeper insights into their morphology. Using visible light, electron, and X-ray microscopy to image diatoms allows for a more comprehensive understanding of their frustules.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Physical
Changhyo Sun, Sang-Jin Ko, Soonho Jung, Chenxi Wang, Donghwa Lee, Jung-Gu Kim, Yunseok Kim
Summary: This study developed a method for differentiating local microstructures on low carbon steel based on multiple physical properties at the nanoscale combined with machine learning techniques. The analysis of corrosion behavior according to the identified local microstructures and obtained physical properties potentially provides a powerful tool for identifying and visualizing features of data. This approach could be expanded to electrochemical systems with more complex microstructures.
APPLIED SURFACE SCIENCE
(2021)
Article
Immunology
Fallon dos Santos Siqueira, Josieli Demetrio Siqueira, Laura Bedin Denardi, Kelly Schneider Moreira, Thiago Augusto Lima Burgo, Lenice de Lourenco Marques, Alencar Kolinski Machado, Carolina Bordin Davidson, Otavio Augusto Chaves, Marli Matiko Anraku de Campos, Davi Fernando Back
Summary: Antibiotic resistance associated with pulmonary infection agents is a pressing public health concern. The synthesis of molecules from pre-existing drugs has shown promise in increasing therapeutic options against resistant microorganisms.
MICROBIAL PATHOGENESIS
(2023)
Article
Nanoscience & Nanotechnology
Haoran Ma, Roland Bennewitz
Summary: In this study, atomic force microscopy was used to investigate nanoscale friction on metallic glasses in corrosive solutions. The results revealed the influence of corrosion on nanoscale friction and provided insights into the physicochemical processes of surface dissolution.
BEILSTEIN JOURNAL OF NANOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Keivan Asadi, Junghoon Yeom, Hanna Cho
Summary: Investigating internal resonance (IR) mechanisms in micro/nanoresonators reveals that intermodal coupling between second and third flexural modes in asymmetric structures provides an optimal condition for strong IR, with high energy transfer to the resonated mode. This study introduces design strategies that can be easily integrated into typical micro/nanoelectromechanical systems, offering potential for paradigm-shifting applications in micro/nanosystems.
MICROSYSTEMS & NANOENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Agata Zdarta, Ewa Kaczorek
Summary: Recognition of the microbial cell's surface constituents' biophysical properties is an important research topic. This study used atomic force microscopy to analyze the nanomechanical changes in probiotic bacteria under exposure to certain antibiotics. The results showed significant changes in cell morphology, topography, and adhesion parameters, indicating the effects of antibiotics on probiotic biofilm formation.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
(2023)
Article
Microbiology
Sven C. J. van Dun, Marielle Verheul, Bart G. C. W. Pijls, Joffrey van Prehn, Henk Scheper, Federica Galli, Peter H. H. Nibbering, Mark G. J. de Boer
Summary: A study investigated the topography of biofilms on different implant materials and their correlation with susceptibility to antimicrobial treatment. The results showed that the surface parameters of MRSA biofilms were determined by the characteristics of the implant materials. There were no significant differences in antibiotic susceptibility among MRSA biofilms on different implant materials.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Kordula B. Schnabl, Laurens D. B. Mandemaker, Klaas G. J. Nierop, Olivier V. B. Deen, Desmond D. Eefting, Ina Vollmer, Bert M. Weckhuysen
Summary: Research shows that chitosan, a strong and workable derivative of chitin obtained from crustaceans, can be used as a renewable alternative to fossil-fuel-based polymer materials. By adding different types of green additives, chitosan-based composites with various properties, from very hard and brittle to soft and flexible, have been successfully produced. These findings open up possibilities for adjusting the properties of chitosan-based polymer materials and applying them in consumer goods.
Editorial Material
Multidisciplinary Sciences
Telmo O. Paiva, Albertus Viljoen, Yves F. Dufrene
Summary: Advancements in atomic force microscopy (AFM) techniques and methodologies in microbiology have enhanced our understanding of microbial cell surfaces. Recent studies have shown that AFM imaging of cells and membranes at or near molecular resolution enables detailed visualization of membrane-drug interactions.
NATURE COMMUNICATIONS
(2022)
Article
Physics, Applied
Shiquan Lin, Zhong Lin Wang
Summary: Inspired by TENG, scanning TENG is proposed for local surface charge density measurement using atomic force microscopy. The technique taps a conductive tip above a charged dielectric surface to induce an AC, with Fourier analysis showing a linear relation to surface charge density. Results demonstrate its power in probing nanoscale charge transfer in contact-electrification.
APPLIED PHYSICS LETTERS
(2021)
Article
Chemistry, Physical
Miles F. Beaux, Reuben J. Peterson, Igor O. Usov
Summary: Atomic force microscopy was used to map the topography and qualitative mechanical characteristics of gallium-stabilized delta-phase plutonium coupons. The initial rough and heterogeneous surface of plutonium was observed, along with distinct striation patterns in qualitative nanomechanical mapping. Investigation suggested that the striations were not measurement artifacts or plutonium-specific features, and were influenced by mechanical working of the surface.
SURFACES AND INTERFACES
(2021)
Article
Microbiology
Helen M. Greer, Kanesha Overton, Megan A. Ferguson, Eileen M. Spain, Louise E. O. Darling, Megan E. Nunez, Catherine B. Volle
Summary: When exposed to the AMP magainin 2, cells in biofilms exhibit varying biomechanical changes, with an increase in the effectiveness of MAG2 on cells achieved through the removal of EPS.
Article
Pharmacology & Pharmacy
Katalin Kristo, Szilvia Modra, Viktoria Hornok, Karoly Suvegh, Krisztina Ludasi, Zoltan Aigner, Andras Kelemen, Tamas Sovany, Klara Pintye-Hodi, Geza Regdon Jr
Summary: This study focused on preparing chitosan films containing ascorbic acid and optimizing their composition to investigate the important properties and structures for applicability. The results showed that ascorbic acid can function as a permeation enhancer in mucoadhesive films and its applicability was confirmed.
Article
Materials Science, Multidisciplinary
Yingyue Yin, Jianhua Zhang, Shengzhao Yang, Tong Liu, Quanquan Han, Zhenhua Zhang, Huanqing Yang
Summary: This study focused on optimizing microstructures for SLM-fabricated HX via heat treatment to enhance its electrochemical dissolution behavior. The rates of electrochemical dissolution with different heat treatments increased in the following order: as-received < solution treatment (ST) < ageing treatment (AT) < solution and ageing treatment (ST + AT) in a 10 wt% NaNO3 solution at 35 degrees C.
MATERIALS & DESIGN
(2021)
Article
Biochemistry & Molecular Biology
Elodie Colaco, Clement Guibert, Jihye Lee, Emmanuel Maisonhaute, Dalil Brouri, Christine Dupont-Gillain, Karim El Kirat, Sophie Demoustier-Champagne, Jessem Landoulsi
Summary: The study introduces an advanced biomimetic approach for designing ordered hybrid mineralized nano-objects with highly anisotropic features, by combining three key concepts in biomineralization. This approach provides new possibilities for bioengineering by controlling the morphology, composition, crystal phase, and mechanical stability of the mineralized nano-objects. Incorporating collagen in the process proved to be an efficient way to enhance mechanical stability and shape control in confined mineralization conditions.
Article
Materials Science, Biomaterials
Cristina Belda Marin, Christophe Egles, Vincent Humblot, Yoann Lalatonne, Laurence Motte, Jessem Landoulsi, Erwann Guenin
Summary: Silk fibroin (SF) is a versatile material with biodegradable and biocompatible properties. Incorporating nanosized objects into SF allows the development of bionanocomposites with tailored functions and properties. The incorporation of gold, silver, or iron oxide nanoparticles into SF hydrogels does not greatly influence gelation mechanism and mechanical properties, but significantly affects swelling behavior, showing potential for biomedical applications like antibacterial and magnetic properties.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Pauline Cornette, Ilhem Lilia Jaabar, Vincent Dupres, Jean-David Werthel, Francis Berenbaum, Xavier Houard, Jessem Landoulsi, Geoffroy Nourissat
Summary: The study investigated the effect of crosslinking treatment on the structure and mechanical properties of diseased human shoulder capsules. The results showed that the crosslinking procedure changed the biomechanics of the capsules while keeping their structural organization unchanged at the single fibril level. This procedure may be a promising way to preserve the functions of collagen-based tissues and tune their elasticity for clinically relevant treatments.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Cristina Belda Marin, Christophe Egles, Jessem Landoulsi, Erwann Guenin
Summary: This study characterized the capacity of silk fibroin hydrogels to absorb dyes and investigated the effect of different pH and ionic environments on pre-treated hydrogels. The hydrogels exhibited absorption ability for cationic dyes, while showing opposite behavior for anionic dyes. Regeneration of the hydrogel was achieved by immersion in acidic pH, and when coupled with gold nanoparticle catalyst, it demonstrated the ability to absorb and catalyze dye reduction.
APPLIED SCIENCES-BASEL
(2022)
Article
Biochemistry & Molecular Biology
Brittany Foley, Clement Guibert, Mohamed Selmane, Alberto Mezzetti, Caroline Lefebvre, Karim El Kirat, Jessem Landoulsi
Summary: In this study, the effects of enzyme substrate concentration and fluoride concentration on the obtained minerals in enzyme-assisted mineralization were investigated. X-ray diffraction, infrared spectroscopy, and X-ray photoelectron spectroscopy were used to analyze the crystal structure and chemical composition of the minerals. The results showed the formation of substituted hydroxyapatite in all conditions, with expansion of the crystal unit cell parameters when the enzyme substrate concentration increased, and contraction of the crystal unit cell parameters and the formation of elongated, well-crystallized rods when the fluoride concentration increased. Complementary IR and XPS data indicated that these trends were explained by the incorporation of substituted ions in the hydroxyapatite lattice at different positions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
C. Methivier, P. Cornette, D. Costa, J. Landoulsi
Summary: In this study, the adsorption behavior of Glu-Cys-Gly peptide on copper surfaces was investigated using the electrospray-ion beam deposition (ES-IBD) method. The results showed that the peptides maintained their molecular structure when adsorbed, and the binding mechanisms were influenced by the copper crystal face. Through DFT calculations and comparison with experimental XPS data, it was found that the peptide adsorbed in a deprotonated state on the copper surface.
APPLIED SURFACE SCIENCE
(2023)
Article
Biophysics
Jihye Lee, Sandra Casale, Jessem Landoulsi, Clement Guibert
Summary: Despite decades of study, the process of calcium phosphate (CaP) biomineralisation is still not well understood due to its complex pathways regulated by biological parameters that are difficult to replicate. This study investigates the catalytic activity of enzymes in directing CaP crystallisation, inspired by the control of CaP biomineralisation in vivo through matrix vesicles (MVs) involving various proteins, including enzymes. The researchers demonstrate how enzymatic control influences the release of phosphate ions, enabling better manipulation of mineral formation, and how it offers insights into the role of magnesium ions as a crystallisation inhibitor.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Physical
Jihye Lee, Adama Konate, Clement Guibert, Jessem Landoulsi
Summary: In this study, a biomimetic method for growing a hybrid calcium phosphate (CaP) - collagen coating is described. The versatility of layer-by-layer (LbL) method is explored to incorporate collagen and alkaline phosphatase (ALP), and control their organization and bioactivity. The presence of collagen fibrils in the LbL film plays a crucial role in the growth mechanism of the biomimetic mineral layer. The approach provides a straightforward way for designing biomimetic hybrid coatings in biomedical applications.
SURFACES AND INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Ilhem Lilia Jaabar, Pauline Cornette, Antoine Miche, Kristell Wanherdrick, Vincent Dupres, Francois-Paul Ehkirch, Adeline Cambon Binder, Francis Berenbaum, Xavier Houard, Jessem Landoulsi
Summary: This article presents a method to study the structure and properties of articular cartilage's extracellular matrix (ECM) in human cartilage tissues. The study found that during the development of osteoarthritis (OA), the ECM undergoes chemical and structural changes, leading to the progression of the disease. Nanoscale characterization studies revealed two stages in the progression of OA and provided mechanistic insights into the initiation and progression of OA in the cartilage ECM. These findings offer guidance for the development of curative treatments.
Meeting Abstract
Orthopedics
I. L. Jaabar, P. Cornette, A. Miche, K. Wanherdrick, V. Dupres, F. Ehkirch, A. Cambon Binder, F. Berenbaum, X. Houard, J. Landoulsi
OSTEOARTHRITIS AND CARTILAGE
(2022)
Meeting Abstract
Biophysics
Borja Rodriguez de Francisco, Isabel Valsecchi, Ariane Pille, Chi L. Pham, Vincent Dupres, Frank Lafont, Jagadesh Bayry, Vishukumar Aimanianda, Margaret Sunde, Inaki Guijarro
BIOPHYSICAL JOURNAL
(2022)
Review
Biochemistry & Molecular Biology
Clement Guibert, Jessem Landoulsi
Summary: Biomineralization is the process by which organisms produce hard inorganic matter from soft tissues, with sophisticated toolkit and biological system regulation in place. Two main views have emerged regarding the mechanism of CaP biomineralization, with one focusing on in vivo systems and the other on physicochemistry research.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Physical
Irma Liascukiene, Gabriel Amselem, Jessem Landoulsi, Deniz Z. Gunes, Charles N. Baroud
Summary: The study showed that coating air bubbles with fat crystals can slow down bubble dissolution but cannot completely prevent it, as the crystals do not provide enough mechanical strength to the bubbles.
Meeting Abstract
Biophysics
Fabio Perissinotto, Sebastien Janel, Javier Lopez-Alonso, Vincent Dupres, Burkhard Bechinger, Frank Lafont, Lorena Redonda-Morata
BIOPHYSICAL JOURNAL
(2021)
