Article
Obstetrics & Gynecology
Samantha Yee, Carly Goodman, Vivian Fu, Nechama J. Lipton, Clifford L. Librach
Summary: The study confirms the significant influence of age and relationship status on women's decisions regarding planned oocyte cryopreservation and utilization of oocytes. Most participants expressed a strong desire for motherhood, with the willingness to use cryopreserved oocytes mostly contingent on their relationship status.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Article
Obstetrics & Gynecology
Jennifer F. Kawwass, Sara Crawford, Heather S. Hipp
Summary: This study aimed to characterize national outcomes of oocyte thaw cycles in the United States and found that pregnancy and live birth rates decreased with increasing age at oocyte cryopreservation, as did the number of oocytes needed to achieve one live birth.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Sarah Druckenmiller Cascante, Jennifer K. Blakemore, Shannon DeVore, Brooke Hodes-Wertz, M. Elizabeth Fino, Alan S. Berkeley, Carlos M. Parra, Caroline McCaffrey, James A. Grifo
Summary: This retrospective study reviewed the outcomes of patients who underwent autologous oocyte thaw after planned oocyte cryopreservation. The study found that the final live birth rate per patient was 39%, which is comparable to in vitro fertilization outcomes for age-matched patients. Age at cryopreservation and the number of thawed metaphase II oocytes were predictive of live birth rates.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Ayse Seyhan, Oznur Dundar Akin, Sinem Ertas, Baris Ata, Kayhan Yakin, Bulent Urman
Summary: The study evaluated the expectations, experiences, and fertility awareness status of women who underwent social oocyte cryopreservation and found that many women lack a realistic understanding of reproductive aging and tend to overestimate the chances of success with frozen oocytes. However, the majority of women still expressed willingness to recommend oocyte cryopreservation to friends.
REPRODUCTIVE SCIENCES
(2021)
Article
Obstetrics & Gynecology
Quinton S. Katler, Lisa M. Shandley, Heather S. Hipp, Jennifer F. Kawwass
Summary: The number of oocyte cryopreservation cycles in the United States has been increasing annually, mainly among patients under 35 years old, with the majority of cycles performed in white patients and a significant increase among Asian patients. There were no clinically significant differences in oocyte yield and maturation percentage across different racial/ethnic groups.
FERTILITY AND STERILITY
(2021)
Review
Medicine, General & Internal
Eric Han, David B. Seifer
Summary: Oocyte cryopreservation (OC) is a process of stimulating ovarian follicles, retrieving follicular fluid, isolating and vitrifying mature oocytes. It has been increasingly used as an option for future biologic children for patients undergoing gonadotoxic therapies. Planned OC, also known as elective OC, is growing in popularity to overcome age-related fertility decline. This review discusses medically indicated and planned OC, focusing on the physiology, technique, timing, financial considerations, and outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Psychology, Clinical
Molly Arendt, Melissa Oxlad
Summary: This study aimed to determine women's views about egg freezing for non-medical reasons and the factors motivating their decisions. A cross-sectional survey was conducted among 514 women aged 18-44 years, revealing that the acceptability of non-medical egg freezing was generally positive, with 61.3% of the participants expressing willingness to consider it. Factors motivating these decisions varied among different groups of women, but the availability of Medicare subsidization and the procedure not affecting future fertility were significant predictors for all groups.
BRITISH JOURNAL OF HEALTH PSYCHOLOGY
(2023)
Review
Obstetrics & Gynecology
Lucy E. Caughey, Sarah Lensen, Katherine M. White, Michelle Peate
Summary: This study conducted a systematic review and meta-analysis on the disposition outcomes and intentions of elective egg freezers, finding that actual EEFs are more willing to donate to research while potential EEFs show a preference for donating to others, with disposition decisions being influenced by various psychosocial factors.
FERTILITY AND STERILITY
(2021)
Article
Biology
Greta Chiara Cermisoni, Valerio Pisaturo, Valeria Stella Vanni, Sabrina Minetto, Luca Pagliardini, Rossella Masciangelo, Massimo Candiani, Enrico Papaleo, Alessandra Alteri
Summary: This paper uses SWOT analysis to evaluate the option of fertility preservation in women with genetic diseases. Strengths include ethical considerations, safety, and effectiveness, while weaknesses are related to costs and risks of maternal complications. Counselling on fertility management offers valuable opportunities, and the use of frozen oocytes can minimize the need for egg donation. However, psychological distress and potential health risks for children conceived after egg vitrification/thawing are threats. Therefore, early counselling on fertility preservation should be incorporated into standard care for all patients with genetic conditions.
Article
Obstetrics & Gynecology
Ashley Wiltshire, Luwam Ghidei, Meralis Lantigua-Martinez, Frederick Licciardi, Jennifer Blakemore
Summary: This study investigated the opinions and attitudes of Black Obstetrician Gynecologists (BOG) towards planned oocyte cryopreservation (POC) and their experiences in counseling patients of color. The results showed that many BOGs felt the need to postpone childbearing due to medical training, and a significant percentage had undergone or planned to undergo POC. Additionally, the study found that medical careers had an unfavorable impact on family building, highlighting the need for a better understanding of mitigating factors to develop culturally appropriate counseling and educational interventions for Black women and other women of color.
REPRODUCTIVE SCIENCES
(2022)
Review
Endocrinology & Metabolism
Eleonora Porcu, Linda Cipriani, Giuseppe Damiano
Summary: Turner syndrome is a genetic pathology that affects about 1/2500 newborn females. It is characterized by deletion or abnormalities of the X chromosome, leading to multiple physical and cognitive anomalies. Reproductive techniques can be used for fertility preservation in women with premature ovarian insufficiency.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Genetics & Heredity
Austin G. Armstrong, Maggie Woods, Jennifer Keomany, David Grainger, Shriya Shah, MaryEllen Pavone
Summary: This study aimed to assess the knowledge and attitudes of medical students towards oocyte cryopreservation and their future intentions of utilizing this procedure. A majority of female medical students were aware of oocyte cryopreservation, but their knowledge regarding fertility and oocyte cryopreservation was low. Most students felt pressure to delay childbearing and would consider freezing their oocytes. Factors such as personal considerations, procedure complexity and availability, and outcomes were found to impact their decision towards oocyte cryopreservation.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2023)
Editorial Material
Obstetrics & Gynecology
Michiel De Proost, Molly Johnston
Summary: France's new bioethics law allows for public funding of both medical and non-medical egg freezing, challenging the use of the medical/non-medical distinction in funding policies and prompting further consideration.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Obstetrics & Gynecology
Jordan P. Duncan, Lucy E. Caughey, Katherine M. White
Summary: This study examined the predictors of willingness to donate frozen oocytes among women of reproductive age in Australia through an online survey. The findings suggested that improving attitudes towards donation and establishing positive images of donors could facilitate frozen oocyte donation, increasing access to oocytes for IVF treatment and reducing psychological burdens associated with infertility.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Obstetrics & Gynecology
Molly Johnston, Nadine M. Richings, Angela Leung, Denny Sakkas, Sally Catt
Summary: The study found that there has been a significant increase in the number of OC cycles performed since 2010, and the demographics of women accessing OC has shifted to a younger age group. However, very few women have returned to use their cryopreserved oocytes in treatments so far.
HUMAN REPRODUCTION
(2021)