Hedgehog signalling as an antagonist of ageing and its associated diseases

The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan

(2011) John R. Speakman et al.   BIOESSAYS

TGF-β Mediates Suppression of Adipogenesis by Estradiol through Connective Tissue Growth Factor Induction

(2011) Ashok Kumar et al.   ENDOCRINOLOGY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Cellular senescence and tumor suppressor gene p16

(2011) Hani Rayess et al.   INTERNATIONAL JOURNAL OF CANCER

Persistent Sonic Hedgehog Signaling in Adult Brain Determines Neural Stem Cell Positional Identity

(2011) Rebecca A. Ihrie et al.   NEURON

Bone Morphogenetic Proteins: A critical review

(2010) Beth Bragdon et al.   CELLULAR SIGNALLING

Targeting Hedgehog -- a Cancer Stem Cell Pathway

(2010) A. A. Merchant et al.   CLINICAL CANCER RESEARCH

Mechanism and evolution of cytosolic Hedgehog signal transduction

(2010) C. W. Wilson et al.   DEVELOPMENT

The Hedgehog morphogen in myocardial ischemia–reperfusion injury

(2010) Maarten F Bijlsma et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hedgehog Signaling Induced by Breast Cancer Cells Promotes Osteoclastogenesis and Osteolysis

(2010) Shamik Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Plasma Very Low Density Lipoprotein Carries Indian Hedgehog

(2010) Karla C. S. Queiroz et al.   JOURNAL OF PROTEOME RESEARCH

Primary Cilium-Dependent and -Independent Hedgehog Signaling Inhibits p16INK4A

(2010) Cleo L. Bishop et al.   MOLECULAR CELL

Ihog and Boi are essential for Hedgehog signaling in Drosophila

(2010) Darius Camp et al.   Neural Development

Sonic Hedgehog Protects Cortical Neurons Against Oxidative Stress

(2010) Ruo-Lian Dai et al.   NEUROCHEMICAL RESEARCH

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

(2010) I. Beerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fgf-9 is required for angiogenesis and osteogenesis in long bone repair

(2010) B. Behr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

When neurogenesis encounters aging and disease

(2010) Orly Lazarov et al.   TRENDS IN NEUROSCIENCES

Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin

(2009) Laure Rittié et al.   AGING CELL

Sonic hedgehog improves delayed wound healing via enhancing cutaneous nitric oxide function in diabetes

(2009) Jian-Dong Luo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ageing as a price of cooperation and complexity

(2009) Huba J. M. Kiss et al.   BIOESSAYS

Sonic hedgehog alleviates the inhibitory effects of high glucose on the osteoblastic differentiation of bone marrow stromal cells

(2009) Cheng-chao Guan et al.   BONE

Bone morphogenetic proteins (BMPs): From morphogens to metabologens

(2009) A. Hari Reddi et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Neurogenesis and Alzheimer's disease: At the crossroads

(2009) Orly Lazarov et al.   EXPERIMENTAL NEUROLOGY

Activation of Wnt/β-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells

(2009) Mounira Abiola et al.   PLoS One

PDGF, TGF- , and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages

(2008) F. Ng et al.   BLOOD

Hedgehog signalling in endocrine development and disease

(2008) Peter J King et al.   JOURNAL OF ENDOCRINOLOGY

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

(2008) Yu-Hua Tseng et al.   NATURE

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

(2008) Young-Goo Han et al.   NATURE NEUROSCIENCE

Patched, the receptor of Hedgehog, is a lipoprotein receptor

(2008) A. Callejo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hedgehog Signaling Alters Adipocyte Maturation of Human Mesenchymal Stem Cells

(2008) Coralie Fontaine et al.   STEM CELLS