Intracellular antibodies and cancer: New technologies offer therapeutic opportunities

Interfering with protein-protein interactions: Potential for cancer therapy

(2011) Tomoyuki Tanaka et al.   CELL CYCLE

Delivery of Therapeutic Proteins

(2010) Dipak S. Pisal et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Recent advances in the use of cell-penetrating peptides for medical and biological applications☆

(2009) Sonali B. Fonseca et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeting LMO2 with a Peptide Aptamer Establishes a Necessary Function in Overt T-Cell Neoplasia

(2009) A. Appert et al.   CANCER RESEARCH

Prevention of oculopharyngeal muscular dystrophy by muscular expression of Llama single-chain intrabodies in vivo

(2009) Aymeric Chartier et al.   HUMAN MOLECULAR GENETICS

Single Chain Variable Fragment against Nicastrin Inhibits the γ-Secretase Activity

(2009) Ikuo Hayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct in Vivo Intracellular Selection of Conformation-sensitive Antibody Domains Targeting Alzheimer's Amyloid-β Oligomers

(2009) Giovanni Meli et al.   JOURNAL OF MOLECULAR BIOLOGY

Protocol for the selection of single-domain antibody fragments by third generation intracellular antibody capture

(2009) Tomoyuki Tanaka et al.   Nature Protocols

Subcellular targeting strategies for drug design and delivery

(2009) Lawrence Rajendran et al.   NATURE REVIEWS DRUG DISCOVERY

Selection of complementary single-variable domains for building monoclonal antibodies to native proteins

(2009) Tomoyuki Tanaka et al.   NUCLEIC ACIDS RESEARCH

Cloning of apoB intrabodies: Specific knockdown of apoB in HepG2 cells

(2008) Wei Liao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Generation of functional scFv intrabody to abate the expression of CD147 surface molecule of 293A cells

(2008) Khajornsak Tragoolpua et al.   BMC BIOTECHNOLOGY

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

Llama-derived single-domain intrabodies inhibit secretion of hepatitis B virions in mice

(2008) Benedikte Serruys et al.   HEPATOLOGY

Single-chain intracellular antibodies inhibit influenza virus replication by disrupting interaction of proteins involved in viral replication and transcription

(2008) Muhammad Mahmood Mukhtar et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

In vivo selection of intrabodies specifically targeting protein–protein interactions: A general platform for an “undruggable” class of disease targets☆

(2008) Michela Visintin et al.   JOURNAL OF BIOTECHNOLOGY

An antibody inhibitor of the LMO2-protein complex blocks its normal and tumorigenic functions

(2008) C-H Nam et al.   ONCOGENE

Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers

(2007) Vladimir P. Torchilin   ADVANCED DRUG DELIVERY REVIEWS

Functional Intracellular Antibody Fragments Do Not Require Invariant Intra-domain Disulfide Bonds

(2007) Tomoyuki Tanaka et al.   JOURNAL OF MOLECULAR BIOLOGY

An scFv Intrabody against the Nonamyloid Component of α-Synuclein Reduces Intracellular Aggregation and Toxicity

(2007) Sandra M. Lynch et al.   JOURNAL OF MOLECULAR BIOLOGY