4.6 Article

A new approach for optical assessment of directional anisotropy in turbid media

期刊

JOURNAL OF BIOPHOTONICS
卷 9, 期 1-2, 页码 100-108

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/jbio.201400124

关键词

directional anisotropy; birefringence; Monte Carlo; out-of-plane; polarized light imaging

资金

  1. NIH [1R15EB013439-01]

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A study of polarized light transport in scattering media exhibiting directional anisotropy or linear birefringence is presented in this paper. Novel theoretical and experimental methodologies for the quantification of birefringent alignment based on out-of-plane polarized light transport are presented here. A polarized Monte Carlo model and a polarimetric imaging system were devised to predict and measure the impact of birefringence on an impinging linearly polarized light beam. Ex-vivo experiments conducted on bovine tendon, a biological sample consisting of highly packed type I collagen fibers with birefringent property, showed good agreement with the analytical results. [GRAPHICS] Top view geometry of the in-plane (a) and the out-of-plane (b) detection. Letter C indicates the location of the detection arm.

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