Article
Chemistry, Multidisciplinary
Tesfay G. Ashebr, Leo La Droitte, Xiao-Lei Li, Chen Zhao, Jinjiang Wu, Quan Zhou, Olivier Cador, Boris Le Guennic, Jinkui Tang
Summary: Using an edaravone-based aryloxide ligand, four new mononuclear Dy(III) compounds were synthesized. The complexes exhibited a slow relaxation of the magnetization, and the magnetic properties were influenced by chemical modifications on the dominant crystal field interaction and the presence of different counterions.
CRYSTAL GROWTH & DESIGN
(2022)
Article
Chemistry, Physical
Minzi Liao, Shengxi Zhao, Kai Wei, Hongwei Sun, Lizhi Zhang
Summary: Oxalated zero-valent iron (Ox-ZVI) efficiently removes Cr(III)-organic complexes without producing toxic Cr(VI). It selectively breaks the Cr-O and Cr-N bonds of Cr(III)-EDTA complexes without generating Cr(VI), achieving 95.4% decomplexation and 94.2% removal of total Cr. The study highlights the importance of adjusting reactive species for precise pollutant control and provides a green and facile method for Cr(III)-organic complexes treatment.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Chemistry, Multidisciplinary
Yashashwa Pandey, Naresh Kumar, Guillaume Goubert, Renato Zenobi
Summary: Raman spectroscopy technology exhibits high resolution and sensitivity in investigating the molecular organization of supported DPPC monolayers, demonstrating the heterogeneity of lipid membranes at the nanoscale.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Natalia Sawicka, Chloe J. Craze, Peter N. Horton, Simon J. Coles, Emma Richards, Simon J. A. Pope
Summary: This study found that chromium(iii) complexes can exhibit near-IR emission at room temperature under aerated solvent conditions through the coordination of bis-terdentate (N^N^N) ligands.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Moritz Bernhardt, Maciej D. D. Korzynski, Zachariah J. J. Berkson, Fabrice Pointillart, Boris Le Guennic, Olivier Cador, Christophe Coperet
Summary: Generating or retaining slow magnetic relaxation in surface-immobilized single-molecule magnets (SMMs) from molecular precursors is a challenging task. However, a material with SMM characteristics has been successfully generated by chemisorption of (Cp-ttt)(2)DyCl on a silica surface containing tailored Lewis acidic Al-(III) sites. Detailed studies reveal slow magnetic relaxation up to 51 K, hysteresis up to 8 K, and an effective energy barrier (U (eff)) of 449 cm(-1), the highest reported for a supported SMM.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Michal Liberka, Mikolaj Zychowicz, Wiktor Zychowicz, Szymon Chorazy
Summary: This method efficiently generates magnetic anisotropy of Dy-III centers by inserting aromatic N-oxide ligands on labile axial positions, providing a novel and convenient route to rationally designed single-molecule magnets.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Kexin Yang, Rong Sun, Jingliang Zhao, Chong Deng, Bingwu Wang, Song Gao, Wenliang Huang
Summary: Molecular design is crucial for improving the performance of single-molecule magnets (SMMs). Enhancing ligand-field axiality is an effective strategy for achieving high-performance dysprosium(III) SMMs. This study synthesized a series of dysprosium(III) complexes and demonstrated their slow magnetic relaxation behavior and high effective barriers, comparable to previously reported complexes. Theoretical calculations also revealed the correlation between the axial ligand's crystal-field parameters and the nitrogen-dysprosium-nitrogen angles, supporting the hypothesis of improving SMM performance through enhancing ligand-field axiality.
INORGANIC CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Marek Szablewski, Richard L. Thompson, Lars-Olof Palsson
Summary: Novel fluorescent Langmuir-Blodgett (LB) films have been constructed from different amphiphilic dicynaoquinodimethanes (DADQs), and the relationship between film structure and fluorescence properties, as well as the response of the films to non-fluorescent target analytes, has been studied. The results show that the modulation of fluorescence varies for different films, which can be attributed to restricted non-radiative decays or charge transfer reactions between target analyte and film.
Article
Chemistry, Inorganic & Nuclear
Zhenhua Zhu, Xu Ying, Chen Zhao, Yi-Quan Zhang, Jinkui Tang
Summary: In this study, a five-coordinate Dy(III) complex was successfully constructed using a super bulky Schiff-base ligand, demonstrating excellent magnetic properties. This represents the best performance among reported mononuclear Ln(III) SMMs with a coordination number less than 6.
INORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Multidisciplinary
Yidian Wang, Qian-Cheng Luo, Yuan-Qi Zhai, Peng-Bo Jin, Zhendong Fu, Qi Sun, Fan-Ni Li, Yan-Zhen Zheng
Summary: In this study, two dysprosium(III) single-molecule magnets (SMMs) were synthesized using a pseudoallyl ligand and pentamethylcyclopentadienyl. The SMMs exhibited distinct energy barriers.
CRYSTAL GROWTH & DESIGN
(2022)
Article
Chemistry, Multidisciplinary
Yidian Wang, Qian-Cheng Luo, Yuan-Qi Zhai, Peng-Bo Jin, Zhendong Fu, Qi Sun, Fan-Ni Li, Yan-Zhen Zheng
Summary: In this study, two dysprosium(III) single-molecule magnets (SMMs) were prepared using a pseudoallyl ligand, N,N'-chelating amidinate (Am), and pentamethylcyclopentadienyl (Cp*). The obtained SMMs, [{(AmiPr)-DyCp*(mu-Cl)}2] and [AmdippDyCp*(Cl)(mu-Cl)Li(THF)3], exhibited distinct energy barriers (Ueff) of 97 and 472 K, respectively, with the latter value similar to a homoleptic Cp*-based Dy-SMM.
CRYSTAL GROWTH & DESIGN
(2022)
Article
Environmental Sciences
Yuxuan Ye, Ning Yang, Lixi Xiao, Qiang Li, Fei Pan, Dongsheng Xia
Summary: In this study, the removal characteristics and mechanisms of Cr(III) complexes were evaluated using Fe(III) coagulation process. The results showed that Fe(III) effectively removed Cr(III)-acetate, while poor removal rate was observed for Cr(III)-citrate. The main removal mechanism of Cr(III)-acetate was precipitation, while Cr(III)-citrate removal relied on adsorption and sweeping effect of Fe floc.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Cong Chen, Pengfei Liu, Yubao Li, Hailong Tian, Yanyang Zhang, Xiangyong Zheng, Renlan Liu, Min Zhao, Xianfeng Huang
Summary: This study achieved efficient removal of Cr(III)-organic complexes and simultaneous recovery of Cr from wastewater by using an electro-peroxone process with activated carbon fiber electrodes. The process effectively curtails the formation of highly toxic Cr(VI) and prevents the generation of Cr enriched waste sludge. Mechanism studies show that the electro-generated H2O2 reacts with O-3 to generate abundant HO., which sequentially oxidizes Cr(III) to Cr(VI). The ACF electrodes demonstrate excellent reusability, and the process is effective for Cr(III) complexed with other ligands and in real electroplating wastewater.
Article
Chemistry, Inorganic & Nuclear
Ashley J. Schuman, Sarah F. T. Robey, Eileen C. Judkins, Matthias Zeller, Tong Ren
Summary: This study describes the synthesis and characterization of macrocyclic Cr-III mono-alkynyl complexes, which were obtained in high yields through chemical reactions. The single crystal X-ray diffraction confirmed the desired structure of these complexes. These complexes exhibit different characteristics in absorption and emission spectra compared to bis-alkynyl complexes.
DALTON TRANSACTIONS
(2021)
Article
Multidisciplinary Sciences
Amna Shoaib, Saba Khurshid, Arshad Javaid
Summary: Contamination of agricultural soil with chromium ions poses a threat to global crop, human, and ecosystem health. This study found that buffel grass can mitigate chromium levels in tomato plants, especially when 2% biomass is added to soil contaminated with Cr(III) and Cr(VI) at 200 and 300 mg/kg.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Medicinal
Rohit Y. Sathe, Seema A. Kulkarni, Raja Natesan Sella, Thirumurthy Madhavan
MEDICINAL CHEMISTRY RESEARCH
(2015)
Article
Pharmacology & Pharmacy
Natesan S. Raja, Balachandran Unni Nair
Article
Biochemistry & Molecular Biology
Manish Dash, Kanagaraj Palaniyandi, Satish Ramalingam, S. Sahabudeen, N. S. Raja
Summary: The study compared three major exosome isolation techniques, TEI, PROSPR, and UC, for their effectiveness in isolating exosomes from cancer cell conditioned media. Through multiple characterization and analysis methods, the study identified advantages, disadvantages, and suitable applications for each technique.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2021)
Review
Biochemistry & Molecular Biology
Harini Hariharan, Yasodha Kesavan, Natesan Sella Raja
Summary: Exosomes are tiny vesicles secreted by most mammalian cells, playing a critical role in cell-to-cell signaling and tumor progression. The release and content of exosomes can be influenced by various physiological factors, altering their biological pathways and potentially affecting tumor behavior.
MOLECULAR BIOLOGY REPORTS
(2021)
Article
Multidisciplinary Sciences
Shruthi Chalil Sureshan, Ruchi Vivekanand Tanavade, Sewali Ghosh, Saswati Ghosh, Raja Natesan Sella, Habeeb Shaik Mohideen
Summary: This study sequenced the complete mitogenome of O. laetus from India, revealing interesting features and providing valuable insights for evolutionary studies of Lygaeidae.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Multidisciplinary
Natesasn Sella Raja, H. Yamini Shrivastava, Balachandran Unni Nair
INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY
(2011)
Article
Biochemistry & Molecular Biology
Philipp Grad, Katarina Edwards, Lars Gedda, Victor Agmo Hernandez
Summary: This study investigates the effects of polyethylene glycol-(PEG) modified lipids and gangliosides on the Ca2+ induced interaction between liposomes composed of palmitoyl-oleoyl phosphatidylethanolamine (POPE) and palmitoyl-oleoyl phosphatidylserine (POPS) at physiological ionic strength. The results show that naked liposomes tend to adhere, rupture, and collapse on each other's surfaces upon addition of Ca2+, eventually resulting in the formation of large multilamellar aggregates and bilayer sheets. However, the presence of gangliosides or PEGylated lipids leads to the formation of small, long-lived bilayer fragments/disks. PEGylated lipids seem to be more effective than gangliosides at stabilizing these structures. The study suggests that direct liposome-liposome fusion is not the dominating process triggered by Ca2+ in the systems studied.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Saurabh Saraswat, Archana Chugh
Summary: Cell penetrating peptides (CPP) are important tools for intracellular delivery of molecules. In this study, a novel marine-derived CPP from Engraulis japonicus, called Engraulisin, was reported. Engraulisin demonstrated successful cellular uptake and selective antimicrobial activity against Methicillin-resistant Staphylococcus aureus (MRSA), making it a potential candidate for drug delivery.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Emanuela Efodili, Ashlynn Knight, Maryem Mirza, Cedric Briones, Il-Hyung Lee
Summary: This study demonstrates the spontaneous transfer of small membrane-bound peptides between a supported lipid bilayer and giant unilamellar vesicles in vitro. The transfer occurs through the formation of hemi-fusion stalks and is limited to small peptides due to the highly curved structure of the stalk. This system provides a synthetic platform for studying peptide trafficking between synthetic membranes.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Yueqi Niu, Si Jia Chen, Jeffery B. Klauda
Summary: Macrophage membranes in the activated state are more tightly packed, exhibit increased chain order across lipid species, and form specific lipid clusters. These findings provide physiologically accurate models for future computational studies of macrophage membranes and their proteins.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Niki Baccile, Vincent Chaleix, Ingo Hoffmann
Summary: This study measured the bending rigidity of self-assembled structures formed by a new biobased glucolipid bioamphiphile using neutron spin-echo (NSE) technology. The results showed that the bending rigidity of these structures is lower or higher compared to phospholipid membranes, providing a new theoretical basis for the application of these new molecular systems.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Alain Bolano Alvares, Pablo E. A. Rodriguez, Gerardo D. Fidelio
Summary: The behavior of amphiphilic molecules at the air/water interface was studied to evaluate the arrangement formed in a confined area. The surface properties of zwitterionic DPPC lipid and A beta(1-40) amyloid peptide in mixed films were investigated at different temperatures. DPPC undergoes a phase transition depending on temperature and lateral pressure, which allows for the study of its influence on amyloid structure formation.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Lukasz Plachta, Marzena Mach, Magdalena Kowalska, Pawel Wydro
Summary: Resveratrol, a popular phytoalexin found in grapes and red wine, has beneficial effects on the cardiovascular system, exhibits antiviral, antibacterial, and antifungal properties, and may have therapeutic effects against cancer. This study investigates the interaction of resveratrol with model cell membranes, demonstrating changes in their physicochemical parameters and highlighting the role of cholesterol content in resveratrol incorporation. The findings suggest that the molecular mechanism of action of resveratrol may involve interactions with lipid rafts.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Edurne Rujas, Beatriz Apellaniz, Johana Torralba, David Andreu, Jose M. M. Caaveiro, Shixia Wang, Shan Lu, Jose L. Nieva
Summary: This study investigates the role of fusion peptide and Trp-rich membrane proximal external region in HIV-1 fusion and demonstrates that liposome-based formulations containing FP-MPER hybrid peptides can induce the production of specific neutralizing antibodies in rabbits. The results support the use of liposomes as vaccine carriers and the inclusion of lipid membranes in immunogens to elicit specific humoral responses.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Dailin Li, Dingyuan Shi, Lei Wang
Summary: G protein-gated inwardly rectifying potassium (GIRK) channels play a significant role in regulating cell excitability. This study investigated the ion permeation mechanism in GIRK2 mutants using molecular dynamic simulations and QM/MM methods. The results revealed the importance of a multi-ion distribution for ion conduction.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Max J. den Uijl, Arnold J. M. Driessen
Summary: Membrane protein insertion into and translocation across the bacterial cytoplasmic membrane are essential processes facilitated by the Sec translocon. The phospholipid dependence of membrane protein insertion has remained mostly unknown. This study reveals that the insertion of the mannitol permease MtlA into the membrane depends on the presence of phosphatidylglycerol and is stimulated by phosphatidylethanolamine.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Patrick Allen, Adam C. Smith, Vernon Benedicto, Abbas Abdulhasan, Vasanthy Narayanaswami, Enrico Tapavicza
Summary: We explore the stability, size, and structure of nanodiscs formed by the N-terminal domain of apolipoprotein E3 and a variable number of 1,2-dimyristoyl-sn-glycero-3-phosphocholine molecules. Our simulations suggest that nanodiscs containing 240 to 420 DMPC molecules are stable. The antiparallel configuration shows more protein-protein interactions and ionic contacts, as well as greater stability and rigidity compared to the parallel configuration.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Patrick M. Keating, Nicholas P. Schifano, Xinrui Wei, Matthew Y. Kong, Jinwoo Lee
Summary: Lassa virus (LASV) infection is dependent on the fusion of its viral membrane with the host cell membrane, and our study reveals that this fusion process involves pH-dependent conformational changes in the transmembrane domain of LASV. These findings provide valuable insights into the fusion mechanism of LASV and can be utilized in the design of therapeutics to combat Lassa virus infections and prevent its potential spread.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Ashley L. Bennett, Kristen N. Cranford, Austin L. Bates, Christopher R. Sabatini, Hee-Seung Lee
Summary: This study employed molecular dynamics simulations to elucidate the binding, folding, and insertion details of TP10W in the cell membrane. The simulations revealed that TP10W can translocate across the lipid membrane as a monomer, and the charged amino acid side chains can move between lipid leaflets. Comparison with point mutated variants demonstrated significant conformational changes due to charge distribution.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Article
Biochemistry & Molecular Biology
Jessica H. van Wonderen, Jason C. Crack, Marcus J. Edwards, Thomas A. Clarke, Gerhard Saalbach, Carlo Martins, Julea N. Butt
Summary: Electrogenic bacteria transfer excess respiratory electrons to metal oxide particles and electrodes through the MtrCAB complex. The crystal structure of MtrCAB from S. baltica OS185 was resolved, and liquid chromatography mass spectrometry was used to determine the mass values of the three proteins in purified MtrCAB complexes.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)
Review
Biochemistry & Molecular Biology
Yi-Ming Chen, Ching-Tai Lu, Chia-Wen Wang, Wolfgang B. Fischer
Summary: A series of dye ligands were ranked based on docking experiments, selecting the most suitable ligands for binding with different proteins. Additionally, a comparison study was conducted on a series of repurposing drugs and known antivirals.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2024)