Poly(A)-binding proteins: Structure, domain organization, and activity regulation

GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation

(2013) Latifa Zekri et al.   EMBO JOURNAL

Post-transcriptional regulation of the human inducible nitric oxide synthase (iNOS) expression by the cytosolic poly(A)-binding protein (PABP)

(2013) Ingrid Casper et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Depletion of Nuclear Poly(A) Binding Protein PABPN1 Produces a Compensatory Response by Cytoplasmic PABP4 and PABP5 in Cultured Human Cells

(2013) Rumpa Biswas Bhattacharjee et al.   PLoS One

Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate

(2013) K.-L. Huang et al.   RNA

Control of Translation and miRNA-Dependent Repression by a Novel Poly(A) Binding Protein, hnRNP-Q

(2013) Yuri V. Svitkin et al.   PLOS BIOLOGY

Poly(A)-binding protein interacts with the nucleocapsid protein of porcine reproductive and respiratory syndrome virus and participates in viral replication

(2012) Xiaoye Wang et al.   ANTIVIRAL RESEARCH

Embryonic poly(A)-binding protein (ePAB) phosphorylation is required forXenopusoocyte maturation

(2012) Kyle Friend et al.   BIOCHEMICAL JOURNAL

The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities

(2012) Matthew Brook et al.   BIOCHEMICAL JOURNAL

Nanopore Detachment Kinetics of Poly(A) Binding Proteins from RNA Molecules Reveals the Critical Role of C-Terminus Interactions

(2012) Jianxun Lin et al.   BIOPHYSICAL JOURNAL

Rotavirus variant replicates efficiently although encoding an aberrant NSP3 that fails to induce nuclear localization of poly(A)-binding protein

(2012) M. M. Arnold et al.   JOURNAL OF GENERAL VIROLOGY

Poly(A)-Binding Protein Facilitates Translation of an Uncapped/Nonpolyadenylated Viral RNA by Binding to the 3' Untranslated Region

(2012) H.-o. Iwakawa et al.   JOURNAL OF VIROLOGY

Evidence Providing New Insights into TOB-Promoted Deadenylation and Supporting a Link between TOB's Deadenylation-Enhancing and Antiproliferative Activities

(2012) N. Ezzeddine et al.   MOLECULAR AND CELLULAR BIOLOGY

Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G

(2012) Nozhat Safaee et al.   MOLECULAR CELL

Bidirectional Control of mRNA Translation and Synaptic Plasticity by the Cytoplasmic Polyadenylation Complex

(2012) Tsuyoshi Udagawa et al.   MOLECULAR CELL

PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding

(2012) Francesca Moretti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC

(2012) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Translational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish

(2012) Y. Mishima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poly(A) binding protein abundance regulates eukaryotic translation initiation factor 4F assembly in human cytomegalovirus-infected cells

(2012) C. McKinney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific PABP effect on translation ofYB-1mRNA is neutralized by polyadenylation through a “mini-loop” at 3′ UTR

(2012) Irina A. Eliseeva et al.   RNA Biology

miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay

(2012) S. Djuranovic et al.   SCIENCE

Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish

(2012) A. A. Bazzini et al.   SCIENCE

A Proline-Tyrosine Nuclear Localization Signal (PY-NLS) Is Required for the Nuclear Import of Fission Yeast PAB2, but Not of Human PABPN1

(2012) Pierre-Luc Mallet et al.   TRAFFIC

Cytoplasmic RNA-Binding Proteins and the Control of Complex Brain Function

(2012) J. C. Darnell et al.   Cold Spring Harbor Perspectives in Biology

Poly(A) binding proteins: are they all created equal?

(2012) Dixie J. Goss et al.   Wiley Interdisciplinary Reviews-RNA

PABP Interacting Protein 2A (PAIP2A) Regulates Specific Key Proteins During Spermiogenesis in the Mouse1

(2011) Geraldine Delbes et al.   BIOLOGY OF REPRODUCTION

The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo

(2011) Navjot Singh et al.   DEVELOPMENTAL BIOLOGY

Pabp binds to the osk 3′UTR and specifically contributes to osk mRNA stability and oocyte accumulation

(2011) Paula Vazquez-Pianzola et al.   DEVELOPMENTAL BIOLOGY

PABP is not essential for microRNA-mediated translational repression and deadenylationin vitro

(2011) Takashi Fukaya et al.   EMBO JOURNAL

Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR

(2011) C. K. Damgaard et al.   GENES & DEVELOPMENT

Makorin Ring Zinc Finger Protein 1 (MKRN1), a Novel Poly(A)-binding Protein-interacting Protein, Stimulates Translation in Nerve Cells

(2011) Hatmone Miroci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose-stimulated Translation Regulation of Insulin by the 5′ UTR-binding Proteins

(2011) Shardul D. Kulkarni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs

(2011) H. M. Burgess et al.   JOURNAL OF CELL SCIENCE

The novel gene twenty-four defines a critical translational step in the Drosophila clock

(2011) Chunghun Lim et al.   NATURE

Structure of Musashi1 in a complex with target RNA: the role of aromatic stacking interactions

(2011) Takako Ohyama et al.   NUCLEIC ACIDS RESEARCH

The Putative RNA Helicase HELZ Promotes Cell Proliferation, Translation Initiation and Ribosomal Protein S6 Phosphorylation

(2011) Philippe A. Hasgall et al.   PLoS One

Interplay between Y-box-binding protein 1 (YB-1) and poly(A) binding protein (PABP) in specific regulation ofYB-1mRNA translation

(2011) Dmitry N. Lyabin et al.   RNA Biology

Translational Control in Oocyte Development

(2011) J. D. Richter et al.   Cold Spring Harbor Perspectives in Biology

Poly(A)-binding protein (PABP): a common viral target

(2010) Richard W. P. Smith et al.   BIOCHEMICAL JOURNAL

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing

(2010) Eric Huntzinger et al.   EMBO JOURNAL

Structural Basis of Binding of P-body-associated Proteins GW182 and Ataxin-2 by the Mlle Domain of Poly(A)-binding Protein

(2010) Guennadi Kozlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice

(2010) Akiko Yanagiya et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein

(2010) Guennadi Kozlov et al.   JOURNAL OF MOLECULAR BIOLOGY

Translational Control of the Abundance of Cytoplasmic Poly(A) Binding Protein in Human Cytomegalovirus-Infected Cells

(2010) C. Perez et al.   JOURNAL OF VIROLOGY

Poly(A)-Binding Protein 1 Partially Relocalizes to the Nucleus during Herpes Simplex Virus Type 1 Infection in an ICP27-Independent Manner and Does Not Inhibit Virus Replication

(2010) C. Salaun et al.   JOURNAL OF VIROLOGY

La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability

(2010) R. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Crossing the borders: Poly(A)-binding proteins working on both sides of the fence

(2010) Jean-François Lemay et al.   RNA Biology

Functional interactions between mRNA turnover and surveillance and the ubiquitin proteasome system

(2010) Seth A. Brooks   Wiley Interdisciplinary Reviews-RNA

Drosophila Larp associates with poly(A)-binding protein and is required for male fertility and syncytial embryo development

(2009) Sarah P. Blagden et al.   DEVELOPMENTAL BIOLOGY

Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin  

(2009) H. Sato et al.   GENES & DEVELOPMENT

Poly(A) Tail Length Is Controlled by the Nuclear Poly(A)-binding Protein Regulating the Interaction between Poly(A) Polymerase and the Cleavage and Polyadenylation Specificity Factor

(2009) Uwe Kühn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly(A)-binding protein binds to the non-polyadenylated 3' untranslated region of dengue virus and modulates translation efficiency

(2009) C. Polacek et al.   JOURNAL OF GENERAL VIROLOGY

Reduction of the Rate of Protein Translation in Patients with Myotonic Dystrophy 2

(2009) C. Huichalaf et al.   JOURNAL OF NEUROSCIENCE

Herpes Simplex Virus Proteins ICP27 and UL47 Associate with Polyadenylate-Binding Protein and Control Its Subcellular Distribution

(2009) E. Dobrikova et al.   JOURNAL OF VIROLOGY

The Silencing Domain of GW182 Interacts with PABPC1 To Promote Translational Repression and Degradation of MicroRNA Targets and Is Required for Target Release

(2009) L. Zekri et al.   MOLECULAR AND CELLULAR BIOLOGY

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

(2009) Marc R. Fabian et al.   MOLECULAR CELL

The SXL-UNR Corepressor Complex Uses a PABP-Mediated Mechanism to Inhibit Ribosome Recruitment to msl-2 mRNA

(2009) Kent E. Duncan et al.   MOLECULAR CELL

GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding

(2009) A. V. Kononenko et al.   NUCLEIC ACIDS RESEARCH

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

(2008) Pavel V Ivanov et al.   EMBO JOURNAL

Expression of poly(A)-binding protein is upregulated during recovery from heat shock in HeLa cells

(2008) Shuhua Ma et al.   FEBS Journal

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP

(2008) Hironori Kawahara et al.   JOURNAL OF CELL BIOLOGY

Rubella Virus Capsid Protein Interacts with Poly(A)-Binding Protein and Inhibits Translation

(2008) C. S. Ilkow et al.   JOURNAL OF VIROLOGY

Cleavage of Poly(A)-Binding Protein by Poliovirus 3C Proteinase Inhibits Viral Internal Ribosome Entry Site-Mediated Translation

(2008) J. M. Bonderoff et al.   JOURNAL OF VIROLOGY

Nuclear Localization of Cytoplasmic Poly(A)-Binding Protein upon Rotavirus Infection Involves the Interaction of NSP3 with eIF4G and RoXaN

(2008) M. Harb et al.   JOURNAL OF VIROLOGY

Genome-Wide Polysome Profiling Reveals an Inflammation-Responsive Posttranscriptional Operon in Gamma Interferon-Activated Monocytes

(2008) K. Vyas et al.   MOLECULAR AND CELLULAR BIOLOGY

Poly(A)-Binding Protein-Interacting Protein 1 Binds to Eukaryotic Translation Initiation Factor 3 To Stimulate Translation

(2008) Y. Martineau et al.   MOLECULAR AND CELLULAR BIOLOGY

Deadenylation is a widespread effect of miRNA regulation

(2008) A. Eulalio et al.   RNA

Modulation of enteroviral proteinase cleavage of poly(A)-binding protein (PABP) by conformation and PABP-associated factors

(2008) Carlos I. Rivera et al.   VIROLOGY

Polyglutamine Genes Interact to Modulate the Severity and Progression of Neurodegeneration in Drosophila

(2008) Derek Lessing et al.   PLOS BIOLOGY

A Competition between Stimulators and Antagonists of Upf Complex Recruitment Governs Human Nonsense-Mediated mRNA Decay

(2008) Guramrit Singh et al.   PLOS BIOLOGY

Squid, Cup, and PABP55B function together to regulate gurken translation in Drosophila

(2007) K. Nicole Clouse et al.   DEVELOPMENTAL BIOLOGY