期刊
BIOCHEMISTRY-MOSCOW
卷 75, 期 4, 页码 383-404出版社
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0006297910040012
关键词
lipopolysaccharide (endotoxin); lipooligosaccharide; lipid A; core; O-antigen; gangliosides; cytokines
This review covers data on composition and structure of lipid A, core, and O-polysaccharide of the known lipopolysaccharides from Gram-negative bacteria. The relationship between the structure and biological activity of lipid A is discussed. The data on roles of core and O-polysaccharide in biological activities of lipopolysaccharides are presented. The structural homology of some oligosaccharide sequences of lipopolysaccharides to gangliosides of human cell membranes is considered.
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