Article
Biotechnology & Applied Microbiology
Anqi Xue, Zuming Mao, Xiaoyu Zhu, Qiang Yang, Peichen Wang, Zimu Mao, Mingze Du, Xu Ma, Dong Jiang, Yubo Fan, Feng Zhao
Summary: This study aimed to investigate the biomechanical effects of horizontal meniscal tears and different resection strategies on a rabbit knee joint using finite element analysis. The results showed that the horizontal meniscal tears had little biomechanical impact on the rabbit knee joint, and some of the partial meniscectomy strategies also had minimal effect on joint stress. It is recommended to preserve the posterior root and the remaining peripheral edge of the meniscus during surgery for a horizontal meniscal tear.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Computer Science, Interdisciplinary Applications
Tinghui Sun, Desmond Y. R. Chong, Bingmei Shao, Zhan Liu
Summary: This study aims to investigate the biomechanical behavior of the human masticatory system and reveal the force transmission patterns using advanced three-dimensional finite element models. The results showed that the molar occlusal surfaces play a primary role in force transmission during clenching. The presence or absence of molar cushions significantly affects the biomechanical response of the masticatory system. This study contributes to a better understanding of force transmission and the significance of temporomandibular joints during the clenching process.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Chemistry, Physical
Guilherme da Rocha Scalzer Lopes, Jefferson David Melo de Matos, Daher Antonio Queiroz, Joao Paulo Mendes Tribst, Nathalia de Carvalho Ramos, Mateus Garcia Rocha, Adriano Baldotto Barbosa, Marco Antonio Bottino, Alexandre Luiz Souto Borges, Renato Sussumu Nishioka
Summary: This study evaluated the biomechanical behavior of Morse taper implants using different abutments for supporting a screw-retained 3-unit fixed partial denture. The results showed that under favorable conditions, the use of CMN or MP abutments to support a fixed partial denture is feasible.
Article
Biology
Wei Fan, Chi Zhang, Qing-Dong Wang, Li-Xin Guo, Ming Zhang
Summary: The biomechanical effects of topping-off instrumentation on the sacroiliac joint (SIJ) after lumbosacral fusion were investigated. It was found that the use of topping-off devices increased motion, stress, and ligament strain at the SIJ, suggesting a higher risk of degeneration and pain compared to fusion alone.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Biology
Maria Prado, Caroline Mascoli, Hugo Giambini
Summary: The L4-L5 spinal segment is associated with lumbar back pain, which can be caused by lumbar disc herniation, intervertebral disc degeneration, or degeneration of the facet joints. This study used a finite element model to analyze the effects of conservative and aggressive percutaneous transforaminal endoscopic discectomy (PTED) and disc degeneration on the biomechanics of the spine. The results indicate that PTED and disc degeneration can change spine kinematics, leading to instability and potential negative outcomes such as facet degeneration and LBP.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Biology
Andreza Costa Dayrell, Cintia Tereza Pimenta de Araujo, Ricardo Lopes Rocha, Cristina Pereira Isolan, Pedro Yoshito Noritomi, Marcelo Ferraz Mesquita
Summary: This study evaluated the stress distribution in mandibular implant-supported prosthesis with an internal connection morse taper interface. The results showed that stress values were evenly distributed to the pen-implant bone and implants in all tested conditions. The increase in applied load did not result in a proportional increase in stress values. Four and five implants had similar mechanical demands and five implants did not provide additional benefits. The stress values of the commercial pure titanium frameworks approached the yield strength of the metal.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Engineering, Biomedical
Shilong Mao, Yang Liu, Fuyou Wang, Peng He, Xianzhe Wu, Xingshuang Ma, Yanfeng Luo
Summary: Artificial joint revision surgery often requires patient-specific prostheses for bone defect repair. This work presents a clinical case on the design and mechanical analysis of 3D-printed porous tantalum prostheses for knee revision, providing useful guidance for designing patient-specific prostheses.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Engineering, Biomedical
Yaqiu Zhang, Ludger Keilig, Istabrak Doersam, Christoph Bourauel
Summary: This study analyzed the effects of intermaxillary elastics on the healthy TMJ and found that there were no significant differences in mandibular movement and stress distribution in the TMJ when using symmetrical OEs.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Orthopedics
Farzaneh Gholamian, Mehran Ashrafi, Ali Moradi
Summary: This study analyzed the biomechanical behavior of an interosseous DRUJ prosthesis under different loading conditions using the finite element method. The results showed that the prosthesis can provide functionality similar to a normal hand for daily activities.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Biology
Jiantao Liu, Yanzheng Gao, Binbin Niu, Jintao Xiu, Hongbo Wang, Yanbiao Wang, Yin Yang
Summary: The novel double-hook clavicular plate shows significant reductions in stress on the bone and screws around the clavicle, as well as helping to alleviate peak stress on the acromion.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Orthopedics
Binglang Xiong, Peng Yang, Tianye Lin, Jingli Xu, Yong Xie, Yongliang Guo, Churong Liu, Qizhao Zhou, Qizhong Lai, Wei He, Qiushi Wei, Qingwen Zhang
Summary: This study constructs a comprehensive simulation method for analyzing the dynamics and contact stress changes of the hip joint throughout a gait cycle. Individualized simulation modeling is achieved based on gait trajectories and CT images. The combination of subject-specific gait and inverse dynamic analysis provides pre-processing parameters for more accurate biomechanical analysis of the hip joint.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Orthopedics
Shaoqun Zhang, Yili Chen, Ruxia Ren, Shunwan Jiang, Yafei Cao, Yikai Li
Summary: This study aimed to elucidate the biomechanical mechanism of sacroiliac joint pain caused by sacroiliac joint subluxation. A finite element model was established to quantify simulate the subluxation, and the results showed that different shifts of the sacroiliac joint led to varying stress and strain on ligaments and articular surfaces, potentially resulting in sacroiliac joint pain.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Computer Science, Interdisciplinary Applications
M. Bola, J. A. Simoes, A. Ramos
Summary: This study developed a finite element model that replicated an experimental simulator of an implanted joint shoulder accurately based on the comparison of measured and calculated strains. The results showed a high correlation coefficient and root-mean-square-error between numerical and experimental results, indicating adequate agreement between the two models. Small strains and changes in load distribution from posterior to anterior region were observed.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Clinical Neurology
Song Ke, Xiwang He, Ming Yang, Shuo Wang, Xueguan Song, Zhonghai Li
Summary: This study investigated the complex biomechanical influences on the lumbar spine with varied facet orientation and tropism through finite element analysis and contour maps visualization. It was found that facet tropism played a more significant role in affecting the lumbar spine, with a higher sagittal orientation increasing the risk of recurrent lumbar disc herniation. These biomechanical findings could provide insights for clinicians to understand the prognosis of certain lumbar degenerative conditions.
Article
Multidisciplinary Sciences
Yonggou Lou, Lei Chen, Hongbing Wu, Sandy To
Summary: The Ti-6Al-4V titanium alloy is a lightweight material widely used in the aerospace industry due to its high specific strength, corrosion resistance, and heat resistance. However, it presents poor machinability and rapid tool wear during processing. By analyzing the influence of cutting speed on ultra-precision cutting of titanium alloy, it was found that better surface quality could be achieved at lower cutting speeds.
Article
Biology
Dylan J. M. Bergen, Qiao Tong, Ankit Shukla, Elis Newham, Jan Zethof, Mischa Lundberg, Rebecca Ryan, Scott E. Youlten, Monika Frysz, Peter I. Croucher, Gert Flik, Rebecca J. Richardson, John P. Kemp, Chrissy L. Hammond, Juriaan R. Metz
Summary: Dermal scales possess a strong osteogenic expression profile similar to bone, enriched in genes favoring collagen matrix growth. Despite differences in developmental processes between scale and endoskeleton, zebrafish scales express a subset of evolutionarily conserved genes relevant to human skeletal diseases.
Article
Biochemical Research Methods
Yushi Yang, Francesco Turci, Erika Kague, Chrissy L. Hammond, John Russo, C. Patrick Royall
Summary: In this study, the collective behavior of 50 zebrafish was investigated in a three-dimensional manner. The researchers found that the fish exhibited a transition from ordered to random behavior when they adapted to new environmental conditions. By quantifying the spatial and temporal correlation functions, the researchers identified two length scales that captured the essence of these behavioral changes. The ratio of these length scales was found to correlate with the polarization of collective motion, which was explained using a simplified model of self-propelled particles with alignment interactions.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Antonio Ballell, Emily J. Rayfield, Michael J. Benton
Summary: This study describes the osteological features and provides a complete reconstruction of the forelimb and hindlimb musculature of the Late Triassic sauropodomorph Thecodontosaurus antiquus. The results suggest that Thecodontosaurus was an agile biped, shedding light on the timing of important modifications in the appendicular musculature during the evolution of sauropodomorphs and their transition to quadrupedalism.
ROYAL SOCIETY OPEN SCIENCE
(2022)
Article
Biology
Case Vincent Miller, Michael Pittman, Xiaoli Wang, Xiaoting Zheng, Jen A. Bright
Summary: This study investigates the diet of extinct birds by using four different proxies to determine their feeding habits. By studying the characteristics of extant birds and applying them to the longipterygid birds, the researchers were able to reveal the diet types and behaviors of these extinct birds.
Article
Ecology
Emma C. Hughes, David P. Edwards, Jen A. Bright, Elliot J. R. Capp, Christopher R. Cooney, Zoe K. Varley, Gavin H. Thomas
Summary: Understanding the origins and conservation of morphological diversity is crucial for determining biogeographical patterns, evolutionary processes, and environmental factors. A study on bird species found that avian morphological diversity is unevenly distributed globally, with dense species packing in tropical hotspots. These regions also exhibit high phenotypic diversity. Evolutionary history plays a key role in shaping these patterns, with old species contributing to niche expansion and young species contributing to niche packing.
Article
Anatomy & Morphology
Josepha Godivier, Elizabeth A. Lawrence, Mengdi Wang, Chrissy L. Hammond, Niamh C. Nowlan
Summary: This study quantified key cellular dynamics involved in growth and morphogenesis of the zebrafish jaw joint and used computational simulations to predict joint development, highlighting the dominant influence of growth anisotropy on joint growth and morphogenesis. The findings contribute to understanding the pathogenesis of developmental joint disorders.
JOURNAL OF ANATOMY
(2022)
Article
Paleontology
Samuel R. R. Cross, Benjamin C. Moon, Thomas L. Stubbs, Emily J. Rayfield, Michael J. Benton
Summary: The study investigates the macroevolution of mosasauroid feeding and locomotory disparity using continuous characters measured from the mandible and forelimb as proxies. It finds that innovation and niche partitioning play important roles in driving morphological disparity. The early evolution of Mosasauroidea is characterized by large shifts in morphology, while the later diversification is associated with the acquisition of novel feeding and locomotory strategies. Major morphological innovations are not associated with evolutionary rate shifts, suggesting constant and greater niche occupation in Late Cretaceous oceans. Biological drivers are found to be the primary sculptors of mosasauroid morphological disparity.
Article
Multidisciplinary Sciences
James R. G. Rawson, Borja Esteve-Altava, Laura B. Porro, Hugo Dutel, Emily J. Rayfield
Summary: The developmental underpinnings and functional consequences of modifications to the limbs during the origin of the tetrapod body plan are well characterized. However, the evolution of the tetrapod skull is less understood. This study quantifies topological changes to cranial anatomy in fossil and living taxa to investigate the impact of bone loss on morphological diversification and identifies a time offset between fin-limb and cranial morphological evolution.
Article
Multidisciplinary Sciences
Antonio Ballell, Michael J. Benton, Emily J. Rayfield
Summary: This study investigates the dental morphofunctional diversity of early dinosaurs and predicts their diets using biomechanical and morphometric methods. The results suggest that early saurischians/theropods were carnivores, while sauropodomorphs underwent a dietary shift from carnivory to herbivory. Early ornithischians were likely omnivores. This early dietary diversity played a fundamental role in the rise of dinosaurs to ecological dominance.
Article
Biology
Zichuan Qin, Chun-Chi Liao, Michael J. Benton, Emily J. Rayfield
Summary: This study investigates the functions and formation process of the hand claws of early-branching maniraptoran dinosaurs using finite element analysis and functional-space analysis. The results show distinct functional divergence among the hand claws, with early-branching ones being used for digging and late-branching ones for display. The study also confirms that most therizinosaurians were herbivores.
COMMUNICATIONS BIOLOGY
(2023)
Article
Anatomy & Morphology
Gregory S. Herbert, Stephen A. Hill, Maria Jose Pio, Ryan Carney, Amber Carlson, Elis Newham, Jen A. Bright
Summary: Several families of neogastropod mollusks have evolved the ability to drill through prey skeletons using their own feeding teeth. Researchers have discovered new articulating surfaces in the teeth of neogastropod mollusks, including saddle joints and tongue-and-groove joints, which optimize contact surface area and disperse impact forces during drilling. This finding provides new insight into the functional interactions between teeth and improves our understanding of predatory feeding in neogastropods.
JOURNAL OF MORPHOLOGY
(2023)
Article
Multidisciplinary Sciences
Leanne A. A. Melbourne, Juliet Brodie, Emily J. J. Rayfield, Danna Titelboim, Oliver T. T. Lord, Daniela N. N. Schmidt
Summary: Coralline algae form complex habitats and are biodiversity hotspots. Climate change may decrease their structural integrity, particularly for southern species. Cellular and mineral properties vary greatly within species, between sites, and over time, with smaller temporal differences compared to spatial differences. Future anthropogenic climate change may result in a loss of habitat complexity in the south and expansion of weaker southern species into northern sites.
SCIENTIFIC REPORTS
(2023)
Article
Cell & Tissue Engineering
Jeremie Zappia, Qiao Tong, Renee Van der Cruyssen, Frederique M. F. Cornelis, Cecile Lambert, Tiago Pinto Coelho, Juliane Grisart, Erika Kague, Rik J. Lories, Marc Muller, Dirk Elewaut, Chrissy L. Hammond, Christelle Sanchez, Yves Henrotin
Summary: Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis. Osteomodulin (OMD), a proteoglycan, is associated with the sclerotic phenotype. This study found that OMD binds to RANKL and inhibits osteoclastogenesis, thus regulating bone remodeling and contributing to bone and cartilage homeostasis. Targeting OMD may be a promising personalized approach for osteoarthritis.
Article
Paleontology
James R. G. Rawson, Laura B. Porro, Elizabeth Martin-Silverstone, Emily J. Rayfield
Summary: By digitally reconstructing the skulls of Whatcheeria using computed tomography data, researchers found unique features such as a narrow skull, a gap between nasal bones, and enlarged anterior fangs. These characteristics suggest that the skull of Whatcheeria was well adapted to resist stresses induced by biting large prey.
JOURNAL OF VERTEBRATE PALEONTOLOGY
(2021)
Article
Multidisciplinary Sciences
William J. Deakin, Philip S. L. Anderson, Wendy den Boer, Thomas J. Smith, Jennifer J. Hill, Martin Rucklin, Philip C. J. Donoghue, Emily J. Rayfield
Summary: The study shows that the earliest jaw shapes were optimized for fast closure and stress resistance, indicating a predatory feeding function. As jawed vertebrates evolved, the optimization of jaw shapes for these functions decreased over time. This continual exploration of previously unoccupied morphospace laid the foundation for diverse feeding strategies and the success of jawed vertebrates.
Article
Biophysics
Nathan D. Camarillo, Rafael Jimenez-Silva, Frances T. Sheehan
Summary: This article discusses the statistical dependence between multiple measurements from the same participant and provides recommendations for using these measurements when they are not independent.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
J. Huet, A. -S. Boureau, A. Sarcher, C. Cornu, A. Nordez
Summary: Standard compression in freehand 3D ultrasound induces a bias in volume calculations, but minimal compression and gel pad methods have similar results. With a trained examiner and precautions, the bias can be minimized and become acceptable in clinical applications.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
C. Lariviere, A. H. Eskandari, H. Mecheri, F. Ghezelbash, D. Gagnon, A. Shirazi-Adl
Summary: Recent developments in musculoskeletal modeling have focused on model customization. Personalization of the spine profile may affect estimates of spinal loading and stability. This study investigates the biomechanical consequences of changes in the spinal profile and finds that personalizing the spine profile has medium to large effects on trunk muscle forces and negligible to small effects on spinal loading and stability.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Luke T. Mattar, Arash B. Mahboobin, Adam J. Popchak, William J. Anderst, Volker Musahl, James J. Irrgang, Richard E. Debski
Summary: Exercise therapy fails in about 25.0% of cases for individuals with rotator cuff tears, and one reason for this failure may be the inability to strengthen and balance the muscle forces that keep the humeral head in the correct position. This study developed computational musculoskeletal models to compare the net muscle force before and after exercise therapy between successfully and unsuccessfully treated patients. The study found that unsuccessfully treated patients had less inferiorly oriented net muscle forces, which may increase the risk of impingement.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Natsuki Sado, Takeshi Edagawa, Toshihide Fujimori, Shogo Hashimoto, Yoshikazu Okamoto, Takahito Nakajima
Summary: The existing methods for predicting hip and lumbosacral joint centres in Japanese adults are biased and differ between sexes. We propose new regression equations that consider soft-tissue thickness, sex differences, and a height-directional measure, and validate them using leave-one-out cross-validation.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Peimin Yu, Xuanzhen Cen, Qichang Mei, Alan Wang, Yaodong Gu, Justin Fernandez
Summary: This study aimed to explore the intra-foot biomechanical differences among individuals with chronic ankle instability (CAI), copers, and healthy individuals during dynamic tasks. The study found that copers and CAI individuals had smaller dorsiflexion angles and copers presented a more eversion position compared to healthy participants. Copers also had greater dorsiflexion angles in the metatarsophalangeal joint and more inversion moments in the subtalar joint during certain tasks. These findings can help in designing interventions to restore ankle joint functions in CAI individuals.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Jon Skovgaard Jensen, Anders Holsgaard-Larsen, Anders Stengaard Sorensen, Per Aagaard, Jens Bojsen-Moller
Summary: This study investigates the biomechanical effects of robot-assisted body weight unloading (BWU) on gait patterns in healthy young adults. The results show that dynamic robot-assisted BWU enables reduced kinetic requirements without distorting biomechanically normal gait patterns during overground walking.
JOURNAL OF BIOMECHANICS
(2024)