Article
Medicine, General & Internal
Cheng-Pang Yang, Kung-Tseng Hung, Chun-Jui Weng, Alvin Chao-Yu Chen, Kuo-Yao Hsu, Yi-Sheng Chan
Summary: The study retrospectively evaluated the clinical outcomes of 61 patients who underwent meniscus repair, with findings showing that patients who received repeated PRP injections post-repair did not show significant differences in functional outcomes and healing rates compared to those who did not receive PRP injections.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Orthopedics
Filippo Migliorini, Luise Schaefer, Andreas Bell, Christian David Weber, Gianluca Vecchio, Nicola Maffulli
Summary: Meniscal repair is associated with a lower risk of progression to knee osteoarthritis compared to partial meniscectomy in patients with symptomatic meniscal tears. No significant differences were found in certain measurements between meniscal repair and resection.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Orthopedics
T. G. van Tienen, B. van Minnen, K. C. Defoort, P. J. Emans, S. A. W. van de Groes, N. Verdonschot, L. M. Jutten, R. W. E. Pikaart, P. J. C. Heesterbeek
Summary: This study evaluated the effects of a polycarbonate anatomical meniscus prosthesis system on knee pain in patients with post-meniscectomy pain syndrome, and found that the prosthesis led to impaired knee function and had serious adverse events. However, one patient showed improvement with the prosthesis still in place.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Orthopedics
A. G. Gouldin, N. K. Patel, G. J. Golladay, J. L. Puetzer
Summary: There is a clear link between increasing age and meniscus degeneration, which leads to increased injury, osteoarthritis progression, and often total knee replacement. Advanced glycation endproducts (AGEs) play a central role in age-related tissue degradation, but their role in meniscus degeneration is not well understood. This study characterized changes in aged osteoarthritic menisci, focusing on zonal AGE accumulation, to gain a better understanding of age-related meniscal degeneration.
OSTEOARTHRITIS AND CARTILAGE
(2023)
Review
Orthopedics
Yi David Diao, Prushoth Vivekanantha, Dan Cohen, Yuichi Hoshino, Kanto Nagai, Darren de SA
Summary: The purpose of this study was to compare post-operative clinical outcomes of discoid meniscus tear procedures with or without repair with those of non-discoid meniscus tears in skeletally mature patients. The study included 38 studies with 2213 patients, and the results showed similar outcomes in terms of Lysholm scores, Tegner scores, and revision rates between discoid and non-discoid procedures. However, patients undergoing discoid procedures had slightly higher Tegner activity scores compared to those undergoing non-discoid procedures.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Orthopedics
Irfan A. Khan, Cristian A. DeSimone, John Hayden Sonnier, John R. Vaile, Donald W. Mazur, Kevin B. Freedman, Yale A. Fillingham
Summary: This study compared the functional outcomes after TKA in patients with and without prior meniscectomy. It was found that patients with prior meniscectomy had worse functional outcomes after TKA and were less likely to achieve the minimal clinically important difference and patient acceptable symptom state for KOOS-JR.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Nam-Hun Lee, Hyoung-Yeon Seo, Myung-Jin Sung, Bo-Ram Na, Eun-Kyoo Song, Jong-Keun Seon
Summary: Both conservative treatment and meniscectomy provided symptomatic relief for degenerative medial meniscus posterior root tear (MMPRT) patients. However, it was found that meniscectomy led to more severe progression of osteoarthritis (OA). In middle-aged patients, arthroscopic meniscectomy showed no advantage over conservative treatment in terms of clinical outcomes and OA progression.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Orthopedics
Sang Hoon Park, Chong Hyuk Choi, Ju Hyung Yoo, Sung Hwan Kim, Han Kook Yoon, Min Jung, Ki Hong Choi, Hyun Soo Moon
Summary: The study aimed to investigate radiographic factors predicting surgical outcomes of arthroscopic partial meniscectomy in elderly patients with mild osteoarthritis. The results showed that meniscus extrusion ratio was the most important predictive factor, with a cutoff point of 34.2% to determine clinically significant improvement, providing guidance for surgical decision-making in this patient population.
JOURNAL OF KNEE SURGERY
(2021)
Article
Biotechnology & Applied Microbiology
Anqi Xue, Zuming Mao, Xiaoyu Zhu, Qiang Yang, Peichen Wang, Zimu Mao, Mingze Du, Xu Ma, Dong Jiang, Yubo Fan, Feng Zhao
Summary: This study aimed to investigate the biomechanical effects of horizontal meniscal tears and different resection strategies on a rabbit knee joint using finite element analysis. The results showed that the horizontal meniscal tears had little biomechanical impact on the rabbit knee joint, and some of the partial meniscectomy strategies also had minimal effect on joint stress. It is recommended to preserve the posterior root and the remaining peripheral edge of the meniscus during surgery for a horizontal meniscal tear.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Luisa de Roy, Daniela Warnecke, Steffen Paul Hacker, Ulrich Simon, Lutz Duerselen, Anita Ignatius, Andreas Martin Seitz
Summary: This tribological in vitro study on ovine knee joints indicated that neither a simulated posterior medial meniscus root tear nor the removal of the medial meniscus resulted in an initially increased whole joint friction.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Medicine, General & Internal
Young Mo Kim, Yong Bum Joo, Byung Kuk An, Ju-Ho Song
Summary: This study aimed to determine whether preoperative factors could predict the hidden unstable flaps in medial meniscus horizontal tear (MMHT). Medical records of 65 patients who underwent arthroscopic partial meniscectomy for isolated MMHT were retrospectively reviewed. Hidden unstable flaps were noted in more than two thirds of patients, and symptom duration and high-grade cartilage wear of the medial femoral condyle were negatively associated with unstable flaps.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Orthopedics
Joshua P. Castle, Toufic R. Jildeh, Farhan Chaudhry, Elizabeth H. G. Turner, Muhammad J. Abbas, Ossama Mahmoud, Meredith Hengy, Kelechi R. Okoroha, T. Sean Lynch
Summary: The purpose of this study was to develop a predictive machine learning model to identify prognostic factors for continued opioid prescriptions after arthroscopic meniscus surgery. The study found that preoperative opioid consumption and male sex were the most significant predictors for sustained opioid use beyond 1 month postoperatively.
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
(2023)
Article
Orthopedics
Ding-yu Wang, Bo Zhang, Yan-zhang Li, Xiang-yu Meng, Dong Jiang, Jia-Kuo Yu
Summary: The long-term chondroprotective effect of meniscal allograft transplant (MAT) and its superiority over meniscectomy were examined in a cohort study. It was found that MAT had moderate advantages in chondroprotection compared with meniscectomy, with graft extrusion distance strongly affecting the chondroprotective effect. Nonextruded meniscal allografts showed similar chondroprotective effects to native menisci, while allografts with an extrusion >3 mm completely lost their function post-meniscectomy.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2022)
Article
Rheumatology
Jan A. van der Voet, Dieuwke Schiphof, Dammis Vroegindeweij, Edwin H. Oei, Sita M. A. Bierma-Zeinstra, Jos Runhaar
Summary: This study validated the significant association between meniscal extrusion and long-term incident knee osteoarthritis (KOA). Two different cohorts were used to evaluate knees with meniscus extrusion, and the results showed that knees with meniscal extrusion had a higher risk of developing KOA.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2023)
Review
Orthopedics
Sonia Bansal, Edward R. Floyd, Michael Kowalski, Elizabeth Aikman, Philip Elrod, Kyley Burkey, Jorge Chahla, Robert F. LaPrade, Suzanne A. Maher, Jennifer L. Robinson, Jay M. Patel
Summary: Meniscal injuries are common in orthopedics, with treatment options ranging from resection to suture repair. Current research focuses on biological and material-based approaches to enhance meniscal healing and repair.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2021)
Article
Orthopedics
Alex H. S. Harris, Alfred C. Kuo, Thomas R. Bowe, Luisa Manfredi, Narlina F. Lalani, Nicholas J. Giori
Summary: Machine learning strategies were used to develop predictive models for TKA patients' postoperative outcomes, with models for Activities of Daily Living, Pain, Symptoms, and Quality of Life showing the highest accuracy. Different strategies varied in terms of accuracy and input requirements, aiding in patient selection and treatment satisfaction.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Orthopedics
Bennett H. Shapiro, Ramsey C. Cheung, Nicholas J. Giori
Summary: A retrospective review of patients undergoing primary TJA at a single VA medical center in 2019 revealed an anti-HCV antibody prevalence of 11.6%, with an overall viremic prevalence of 0.4%. There was a significant decrease in the prevalence of HCV viremia compared to a prior cohort from 2007 to 2009.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Orthopedics
Sahitya K. Denduluri, Steven T. Woolson, Pier F. Indelli, Edward R. Mariano, Alex H. S. Harris, Nicholas J. Giori
Summary: Evidence from a study spanning 6 years showed that cannabinoid use among total joint arthroplasty patients increased by 60%, while opioid use decreased by approximately 30%. Despite cannabinoid users being more likely to be taking opioids, cannabinoid use did not appear to be associated with perioperative complications.
Editorial Material
Orthopedics
Nicholas J. Giori
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2021)
Article
Medicine, General & Internal
Nicholas J. Giori, John Radin, Alison Callahan, Jason A. Fries, Eni Halilaj, Christopher Re, Scott L. Delp, Nigam H. Shah, Alex H. S. Harris
Summary: This study used 18 years of electronic health records data from the largest integrated health care system in the United States to show that the data completeness improved over time and can provide clinically meaningful data on trends in implant use and identification of poor implants that were subsequently recalled.
Editorial Material
Orthopedics
Nicholas J. Giori
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2022)
Editorial Material
Orthopedics
Nicholas J. Giori
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2022)
Article
Health Care Sciences & Services
Amy K. Rosen, Erin E. Beilstein-Wedel, Alex H. S. Harris, Michael Shwartz, Megan E. Vanneman, Todd H. Wagner, Nicholas J. Giori
Summary: This study compared the rates of hospital readmissions following TKAs performed in VA versus those purchased through CC, and found that nationally, the risk of readmission was significantly lower for TKAs performed in VA. Most VA facilities performed similarly to their corresponding CC providers, but there were a few VA facilities that performed worse.
Article
Orthopedics
Vineet Tyagi, Alex H. S. Harris, Nicholas J. Giori
Summary: This study investigated the effect of HA coating on component revision after total hip arthroplasty (THA) in the veteran population. The results showed that HA coating did not improve the survival of THA implants, suggesting that its general use is not supported.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Alex H. S. Harris, Amber W. Trickey, Hyrum S. Eddington, Carolyn D. Seib, Robin N. Kamal, Alfred C. Kuo, Qian Ding, Nicholas J. Giori
Summary: The study aimed to develop, validate, and estimate the accuracy of risk prediction models for 30-day mortality and complications after hip fracture surgery, evaluate risk prediction thresholds for identifying very high-risk patients, and implement the models in an accessible web calculator. The models showed good discrimination and calibration, with high specificity but also high false discovery rates in identifying very high-risk patients. The tool developed could be useful for personalized informed consent and shared decision-making with patient-specific risk estimates.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2022)
Article
Orthopedics
Elizabeth B. Habermann, Alex H. S. Harris, Nicholas J. Giori
Summary: Direct data abstraction from patient charts has been the gold standard for quality and accuracy in medical research. This article reviews two programs that circumvent the high personnel costs by utilizing trained abstractors. These programs provide important benchmarks for big data efforts.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2022)
Article
Medicine, General & Internal
Nicholas J. Giori, Erin E. Beilstein-Wedel, Michael Shwartz, Alex H. S. Harris, Megan E. Vanneman, Todd H. Wagner, Amy K. Rosen
Summary: According to this study, there is no association between surgical quality and the choice of healthcare facility for veterans undergoing total knee arthroplasty (TKA), possibly due to the lack of meaningful comparative data. Reporting risk-standardized complication rates may improve care and help veterans make informed decisions.
Editorial Material
Orthopedics
Nicholas J. Giori
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2023)
Article
Orthopedics
Kristine Godziuk, Emily A. A. Reeson, Alex H. S. Harris, Nicholas J. J. Giori
Summary: The use of a patient body mass index (BMI) eligibility threshold for total joint arthroplasty (TJA) is a controversial topic. Orthopaedic surgeons' perspectives on this issue vary, and there are multiple factors that influence their decision-making.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2023)
Article
Orthopedics
Foster Chen, Nicholas Giori
Summary: Accurate templating for arthroplasty procedures relies on reliably estimating image magnification. The authors' simple device using staggered marker balls in orthogonal imaging proved to be more precise compared to assuming a constant 20% magnification for all x-rays, with the novel technique having no outliers exceeding 4% error.
TECHNIQUES IN ORTHOPAEDICS
(2021)
Article
Biophysics
Nathan D. Camarillo, Rafael Jimenez-Silva, Frances T. Sheehan
Summary: This article discusses the statistical dependence between multiple measurements from the same participant and provides recommendations for using these measurements when they are not independent.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
J. Huet, A. -S. Boureau, A. Sarcher, C. Cornu, A. Nordez
Summary: Standard compression in freehand 3D ultrasound induces a bias in volume calculations, but minimal compression and gel pad methods have similar results. With a trained examiner and precautions, the bias can be minimized and become acceptable in clinical applications.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
C. Lariviere, A. H. Eskandari, H. Mecheri, F. Ghezelbash, D. Gagnon, A. Shirazi-Adl
Summary: Recent developments in musculoskeletal modeling have focused on model customization. Personalization of the spine profile may affect estimates of spinal loading and stability. This study investigates the biomechanical consequences of changes in the spinal profile and finds that personalizing the spine profile has medium to large effects on trunk muscle forces and negligible to small effects on spinal loading and stability.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Luke T. Mattar, Arash B. Mahboobin, Adam J. Popchak, William J. Anderst, Volker Musahl, James J. Irrgang, Richard E. Debski
Summary: Exercise therapy fails in about 25.0% of cases for individuals with rotator cuff tears, and one reason for this failure may be the inability to strengthen and balance the muscle forces that keep the humeral head in the correct position. This study developed computational musculoskeletal models to compare the net muscle force before and after exercise therapy between successfully and unsuccessfully treated patients. The study found that unsuccessfully treated patients had less inferiorly oriented net muscle forces, which may increase the risk of impingement.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Natsuki Sado, Takeshi Edagawa, Toshihide Fujimori, Shogo Hashimoto, Yoshikazu Okamoto, Takahito Nakajima
Summary: The existing methods for predicting hip and lumbosacral joint centres in Japanese adults are biased and differ between sexes. We propose new regression equations that consider soft-tissue thickness, sex differences, and a height-directional measure, and validate them using leave-one-out cross-validation.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Peimin Yu, Xuanzhen Cen, Qichang Mei, Alan Wang, Yaodong Gu, Justin Fernandez
Summary: This study aimed to explore the intra-foot biomechanical differences among individuals with chronic ankle instability (CAI), copers, and healthy individuals during dynamic tasks. The study found that copers and CAI individuals had smaller dorsiflexion angles and copers presented a more eversion position compared to healthy participants. Copers also had greater dorsiflexion angles in the metatarsophalangeal joint and more inversion moments in the subtalar joint during certain tasks. These findings can help in designing interventions to restore ankle joint functions in CAI individuals.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Jon Skovgaard Jensen, Anders Holsgaard-Larsen, Anders Stengaard Sorensen, Per Aagaard, Jens Bojsen-Moller
Summary: This study investigates the biomechanical effects of robot-assisted body weight unloading (BWU) on gait patterns in healthy young adults. The results show that dynamic robot-assisted BWU enables reduced kinetic requirements without distorting biomechanically normal gait patterns during overground walking.
JOURNAL OF BIOMECHANICS
(2024)