4.5 Article

A novel method of fabricating carbon nanotubes-polydimethylsiloxane composite electrodes for electrocardiography

期刊

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
卷 26, 期 16, 页码 1229-1235

出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/09205063.2015.1082807

关键词

polydimethylsiloxane; carbon nanotubes; composite electrode; dispersion; electrocardiography

资金

  1. Science and Technology Commission of Shanghai Municipality [12411951900, 2014MH031]

向作者/读者索取更多资源

Polymer-based flexible electrodes are receiving much attention in medical applications due to their good wearing comfort. The current fabrication methods of such electrodes are not widely applied. In this study, polydimethylsiloxane (PDMS) and conductive additives of carbon nanotubes (CNTs) were employed to fabricate composite electrodes for electrocardiography (ECG). A three-step dispersion process consisting of ultrasonication, stirring, and in situ polymerization was developed to yield homogenous CNTs-PDMS mixtures. The CNTs-PDMS mixtures were used to fabricate CNTs-PDMS composite electrodes by replica technology. The influence of ultrasonication time and CNT concentration on polymer electrode performance was evaluated by impedance and ECG measurements. The signal amplitude of the electrodes prepared using an ultrasonication time of 12h and CNT content of 5wt% was comparable to that of commercial Ag/AgCl electrodes. The polymer electrodes were easily fabricated by conventional manufacturing techniques, indicating a potential advantage of reduced cost for mass production.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
Article Engineering, Biomedical

Characterization of gelatin-based wound dressing biomaterials containing increasing coconut oil concentrations

Mehlika Karamanlioglu, Serap Yesilkir-Baydar

Summary: This study determined the influence and ideal ratios of different amounts of coconut oil in gelatin-based films as wound dressings. Increasing coconut oil content improved the mechanical properties, thermal stability, cell viability, and wound healing ability of the films. CO-2 and CO-4 showed the best performance among the samples.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2024)

Article Engineering, Biomedical

Cell culture design for homogeneous proliferation of cells in three-dimensional nonwoven polymer scaffolds

Yu-Min Chen, Chihoko Tokoda, Yasuhiko Tabata

Summary: The objective of this study is to establish strategies to uniformly proliferate cells in a three-dimensional nonwoven PET/EVOH scaffold by simple adjustments in seeding and culture methods and the scaffold design. The combination of dynamic and static seeding methods resulted in the highest seeding efficiency. Stirring culture allowed cells to proliferate to a greater extent, while opening holes in the scaffold improved cell distribution. Two 1-mm holes were found to be optimal for homogeneous cell proliferation. Different cell types showed similar behavior in the scaffold, indicating the applicability of the established procedure. The nonwoven PET/EVOH scaffold serves as a potential cell culture substrate for efficient cell proliferation.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2024)

Article Engineering, Biomedical

Development of kojic acid loaded collagen-chitosan nanoparticle as skin lightener product: in vitro and in vivo assessment

Majid Saeedi, Katayoun Morteza-Semnani, Jafar Akbari, Seyyed Mobin Rahimnia, Fatemeh Ahmadi, Hanieh Choubdari, Amir Lotfi, Seyyed Mohammad Hassan Hashemi

Summary: In this study, kojic acid loaded chitosan/collagen nanoparticles were produced using an ionic gelation and ultrasonic approach to enhance dermal delivery and anti-pigmentation effects. Increasing the amount of collagen in the nanoparticles led to larger particle size and higher entrapment efficiency of kojic acid. The nanoparticles were found to be spherical in shape and kojic acid was in an amorphous form. Skin permeability tests showed that the nanoparticles delivered more kojic acid to the dermal layers compared to plain gel. The nanoparticles were non-toxic and non-irritating, and exhibited stronger inhibition of melanin formation compared to free kojic acid. These findings suggest that the produced nanoparticles have potential as a nano-vehicle for dermal administration of kojic acid, providing new options for managing hyper-melanogenesis problems.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2024)

Article Engineering, Biomedical

The role of chitosan in enhancing the solubility and antibacterial activity of emodin against drug-resistant bacteria

Hue Thi Nguyen, Anh-Tuan Le, Thanh Thuy Nguyen, Tran Quang Huy, Thuy Thi Thu Nguyen

Summary: In this study, a chitosan and emodin formulation was prepared to enhance the solubility of emodin and exhibited synergic antibacterial activity against drug-resistant bacterial strains. The enhanced solubility of the formulation suggests its potential as a candidate for the treatment of infectious diseases caused by drug-resistant bacterial pathogens.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2024)

Article Engineering, Biomedical

Synthesis, characterization, and antibacterial activity of chitosan-chelated silver nanoparticles

Jiu Ge, Mengting Li, Jiahui Fan, Christian Celia, Yijun Xie, Qing Chang, Xiaoyong Deng

Summary: Bacterial infections pose a significant threat to human health, and the emergence of multidrug-resistant bacteria has reduced the effectiveness of antibacterial treatments. In this study, chitosan/silver nanoparticle complexes were developed to inhibit bacterial proliferation and induce membrane damage. The results demonstrated that increasing the chitosan concentration enhanced the antibacterial impact, and the nanoparticles showed broad-spectrum antimicrobial activity. The study provides valuable insights into the development of nano-antibacterial agents as a potential substitute for traditional antibiotics in medical applications.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2024)