Signalling specificity in the Akt pathway in breast cancer

Phosphorylation of AKT: a Mutational Analysis.

(2015) Jonathan R. Hart et al.   Oncotarget

AKT3 regulates ErbB2, ErbB3 and estrogen receptor α expression and contributes to endocrine therapy resistance of ErbB2+ breast tumor cells from Balb-neuT mice

(2014) Nicole Grabinski et al.   CELLULAR SIGNALLING

Phosphoproteomics Screen Reveals Akt Isoform-Specific Signals Linking RNA Processing to Lung Cancer

(2014) Ioannis Sanidas et al.   MOLECULAR CELL

PTEN-Deficient Tumors Depend on AKT2 for Maintenance and Survival

(2014) Y. R. Chin et al.   Cancer Discovery

Targeting Akt3 Signaling in Triple-Negative Breast Cancer

(2013) Y. R. Chin et al.   CANCER RESEARCH

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

(2012) Chia-Hsin Chan et al.   CELL

Novel classes of non-coding RNAs and cancer

(2012) Jiri Sana et al.   Journal of Translational Medicine

Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer

(2011) E E Vincent et al.   BRITISH JOURNAL OF CANCER

The Akt kinases: Isoform specificity in metabolism and cancer

(2011) Eva Gonzalez et al.   CELL CYCLE

Oxidation of Akt2 kinase promotes cell migration and regulates G1-S transition in the cell cycle

(2011) Revati Wani et al.   CELL CYCLE

Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H2O2

(2011) Vittoria Cenni et al.   MOLECULAR BIOLOGY OF THE CELL

Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species

(2011) R. Wani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt isoform-specific signaling in breast cancer

(2011) Y. Rebecca Chin et al.   Cell Adhesion & Migration

Promiscuous affairs of PKB/AKT isoforms in metabolism

(2011) Simon M. Schultze et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

The Actin-Bundling Protein Palladin Is an Akt1-Specific Substrate that Regulates Breast Cancer Cell Migration

(2010) Y. Rebecca Chin et al.   MOLECULAR CELL

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

(2010) C. G. Fedele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt-RSK-S6 Kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases

(2010) A. Moritz et al.   Science Signaling

The Akt isoforms are present at distinct subcellular locations

(2009) Stacey A. Santi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Evidence that Inositol Polyphosphate 4-Phosphatase Type II Is a Tumor Suppressor that Inhibits PI3K Signaling

(2009) Christina Gewinner et al.   CANCER CELL

Akt1 and Akt2 Play Distinct Roles in the Initiation and Metastatic Phases of Mammary Tumor Progression

(2009) R. L. Dillon et al.   CANCER RESEARCH

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

(2009) Daming Gao et al.   NATURE CELL BIOLOGY

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

(2009) Hui-Kuan Lin et al.   NATURE CELL BIOLOGY

Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling

(2009) E. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

(2009) W.-L. Yang et al.   SCIENCE

MicroRNAs Differentially Regulated by Akt Isoforms Control EMT and Stem Cell Renewal in Cancer Cells

(2009) D. Iliopoulos et al.   Science Signaling

Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes

(2008) Yvonne Ng et al.   Cell Metabolism

Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer

(2008) Y. Rebecca Chin et al.   CELLULAR SIGNALLING